Insertion sequence inversions mediated by ectopic recombination between terminal inverted repeats. [PDF]
Transposable elements are widely distributed and diverse in both eukaryotes and prokaryotes, as exemplified by DNA transposons. As a result, they represent a considerable source of genomic variation, for example through ectopic (i.e.
Alison Ling, Richard Cordaux
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Comparative analysis of repeat content in plant genomes, large and small
The DNA Features pipeline is the analysis pipeline at EMBL-EBI that annotates repeat elements, including transposable elements. With Ensembl’s goal to stay at the cutting edge of genome annotation, we proved that this pipeline needed an update.
Joris Argentin +4 more
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Mobilization of DNA transposable elements from lentiviral vectors [PDF]
With the Sleeping Beauty (SB) DNA transposon, a reconstructed Tc1/mariner element, as the driving force, DNA transposable elements have emerged as new gene delivery vectors with therapeutic potential. The bipartite transposon vector system consists of a transposon vector carrying the transgene and a source of the transposase that catalyzes transposon ...
Rasmus O, Bak, Jacob Giehm, Mikkelsen
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Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males
Selfish DNA such as transposable elements cause intragenomic conflict. This study finds that on an evolutionarily young, gene-rich Drosophila Y chromosome, transposable elements evade heterochromatic suppression, leading to elevated transposition rates ...
Kevin H.-C. Wei +2 more
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Transposable elements and circular DNAs [PDF]
Circular DNAs are extra-chromosomal fragments that become circularized by genomic recombination events. We have recently shown that yeast LTR elements generate circular DNAs through recombination events between their flanking long terminal repeats (LTRs).
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Whole genome resequencing reveals natural target site preferences of transposable elements in Drosophila melanogaster. [PDF]
Transposable elements are mobile DNA sequences that integrate into host genomes using diverse mechanisms with varying degrees of target site specificity.
Raquel S Linheiro, Casey M Bergman
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Transposons are mobile genetic elements that have invaded all domains of life by moving between and within their host genomes. Due to their mobility (or transposition), transposons facilitate horizontal gene transfer in bacteria and foster the evolution of new molecular functions in prokaryotes and eukaryotes.
Michael Schmitz, Irma Querques
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Sex and the TEs: transposable elements in sexual development and function in animals
Transposable elements are endogenous DNA sequences able to integrate into and multiply within genomes. They constitute a major source of genetic innovations, as they can not only rearrange genomes but also spread ready-to-use regulatory sequences able to
Corentin Dechaud +3 more
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Genomic organization of H2Av containing nucleosomes in Drosophila heterochromatin. [PDF]
H2Av is a versatile histone variant that plays both positive and negative roles in transcription, DNA repair, and chromatin structure in Drosophila.
Zhenhai Zhang, B Franklin Pugh
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Author Correction: Regulation of transposable elements by DNA modifications [PDF]
The originally published article contained an error in Figure 2a: for the left side of the figure part (showing piRNA-directed DNA methylation of mouse transposable elements), DNMT3A/B should have been DNMT3C. The article has now been corrected online.
Özgen Deniz +2 more
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