Results 11 to 20 of about 66,436 (304)
Transposable Elements: From DNA Parasites to Architects of Metazoan Evolution [PDF]
Genes, 2012 One of the most unexpected insights that followed from the completion of the human genome a decade ago was that more than half of our DNA is derived from transposable elements (TEs). Due to advances in high throughput sequencing technologies it is now clear that TEs comprise the largest molecular class within most metazoan genomes.
Piskurek, Oliver, Jackson, Daniel John
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Scientific Reports, 2022 Global changes in DNA methylation are observed in development and disease, and single-cell analyses are highlighting the heterogeneous regulation of these processes.
Kooper V. Hunt +7 more
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Insertion sequence inversions mediated by ectopic recombination between terminal inverted repeats. [PDF]
PLoS ONE, 2010 Transposable elements are widely distributed and diverse in both eukaryotes and prokaryotes, as exemplified by DNA transposons. As a result, they represent a considerable source of genomic variation, for example through ectopic (i.e.
Alison Ling, Richard Cordaux
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Comparative analysis of repeat content in plant genomes, large and small
Frontiers in Plant Science, 2023 The DNA Features pipeline is the analysis pipeline at EMBL-EBI that annotates repeat elements, including transposable elements. With Ensembl’s goal to stay at the cutting edge of genome annotation, we proved that this pipeline needed an update.
Joris Argentin +4 more
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Mobilization of DNA transposable elements from lentiviral vectors [PDF]
Mobile Genetic Elements, 2011 With the Sleeping Beauty (SB) DNA transposon, a reconstructed Tc1/mariner element, as the driving force, DNA transposable elements have emerged as new gene delivery vectors with therapeutic potential. The bipartite transposon vector system consists of a transposon vector carrying the transgene and a source of the transposase that catalyzes transposon ...
Rasmus O, Bak, Jacob Giehm, Mikkelsen
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Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males
Nature Communications, 2020 Selfish DNA such as transposable elements cause intragenomic conflict. This study finds that on an evolutionarily young, gene-rich Drosophila Y chromosome, transposable elements evade heterochromatic suppression, leading to elevated transposition rates ...
Kevin H.-C. Wei +2 more
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Transposable elements and circular DNAs [PDF]
Mobile Genetic Elements, 2016 Circular DNAs are extra-chromosomal fragments that become circularized by genomic recombination events. We have recently shown that yeast LTR elements generate circular DNAs through recombination events between their flanking long terminal repeats (LTRs).
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DNA-binding activity and subunit interaction of the mariner transposase [PDF]
, 2001 Mos1 is a member of the mariner/Tc1 family of transposable elements originally identified in Drosophila mauritiana. It has 28 bp terminal inverted repeats and like other elements of this type it transposes by a cut and paste mechanism, inserts at TA ...
Finnegan, D J, Dawson, A, Zhang, Lei
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Whole genome resequencing reveals natural target site preferences of transposable elements in Drosophila melanogaster. [PDF]
PLoS ONE, 2012 Transposable elements are mobile DNA sequences that integrate into host genomes using diverse mechanisms with varying degrees of target site specificity.
Raquel S Linheiro, Casey M Bergman
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A comparative study of Tam3 and Ac transposition in transgenic tobacco and petunia plants [PDF]
, 1989 Transposition of the Anthirrinum majus Tam3 element and the Zea mays Ac element has been monitored in petunia and tobacco plants. Plant vectors were constructed with the transposable elements cloned into the leader sequence of a marker gene ...
Michel A. Haring +24 more
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