Insertion sequence inversions mediated by ectopic recombination between terminal inverted repeats. [PDF]
PLoS ONE, 2010 Transposable elements are widely distributed and diverse in both eukaryotes and prokaryotes, as exemplified by DNA transposons. As a result, they represent a considerable source of genomic variation, for example through ectopic (i.e.
Alison Ling, Richard Cordaux
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Comparative analysis of repeat content in plant genomes, large and small
Frontiers in Plant Science, 2023 The DNA Features pipeline is the analysis pipeline at EMBL-EBI that annotates repeat elements, including transposable elements. With Ensembl’s goal to stay at the cutting edge of genome annotation, we proved that this pipeline needed an update.
Joris Argentin +4 more
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Mobilization of DNA transposable elements from lentiviral vectors [PDF]
Mobile Genetic Elements, 2011 With the Sleeping Beauty (SB) DNA transposon, a reconstructed Tc1/mariner element, as the driving force, DNA transposable elements have emerged as new gene delivery vectors with therapeutic potential. The bipartite transposon vector system consists of a transposon vector carrying the transgene and a source of the transposase that catalyzes transposon ...
Rasmus O, Bak, Jacob Giehm, Mikkelsen
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Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males
Nature Communications, 2020 Selfish DNA such as transposable elements cause intragenomic conflict. This study finds that on an evolutionarily young, gene-rich Drosophila Y chromosome, transposable elements evade heterochromatic suppression, leading to elevated transposition rates ...
Kevin H.-C. Wei +2 more
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Evolutionary genomics of transposable elements in Saccharomyces cerevisiae [PDF]
, 2012 Saccharomyces cerevisiae is one of the premier model systems for studying the genomics and evolution of transposable elements. The availability of the S.
Bensasson, Douda +8 more
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Transposable elements and circular DNAs [PDF]
Mobile Genetic Elements, 2016 Circular DNAs are extra-chromosomal fragments that become circularized by genomic recombination events. We have recently shown that yeast LTR elements generate circular DNAs through recombination events between their flanking long terminal repeats (LTRs).
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The effects of recombination rate on the distribution and abundance of transposable elements [PDF]
, 2008 Transposable elements (TEs) often accumulate in regions of the genome with suppressed recombination. But it is unclear whether this pattern reflects a reduction in the efficacy of selection against deleterious insertions or a relaxation of ectopic ...
Charlesworth, Brian, Dolgin, Elie S.
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DNA-binding activity and subunit interaction of the mariner transposase [PDF]
, 2001 Mos1 is a member of the mariner/Tc1 family of transposable elements originally identified in Drosophila mauritiana. It has 28 bp terminal inverted repeats and like other elements of this type it transposes by a cut and paste mechanism, inserts at TA ...
Finnegan, D J, Dawson, A, Zhang, Lei
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Whole genome resequencing reveals natural target site preferences of transposable elements in Drosophila melanogaster. [PDF]
PLoS ONE, 2012 Transposable elements are mobile DNA sequences that integrate into host genomes using diverse mechanisms with varying degrees of target site specificity.
Raquel S Linheiro, Casey M Bergman
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FEBS Open Bio, 2023 Transposons are mobile genetic elements that have invaded all domains of life by moving between and within their host genomes. Due to their mobility (or transposition), transposons facilitate horizontal gene transfer in bacteria and foster the evolution of new molecular functions in prokaryotes and eukaryotes.
Michael Schmitz, Irma Querques
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