Transposable Elements, Inflammation, and Neurological Disease. [PDF]
Transposable Elements (TE) are mobile DNA elements that can replicate and insert themselves into different locations within the host genome. Their propensity to self-propagate has a myriad of consequences and yet their biological significance is not well-
Macia, Angela+2 more
core +2 more sources
Full-length autonomous transposable elements are preferentially targeted by expression-dependent forms of RNA-directed DNA methylation [PDF]
BackgroundChromatin modifications such as DNA methylation are targeted to transposable elements by small RNAs in a process termed RNA-directed DNA methylation (RdDM). In plants, canonical RdDM functions through RNA polymerase IV to reinforce pre-existing
Kaushik Panda+5 more
semanticscholar +2 more sources
Detection of DNA Methylation Changes Surrounding Transposable Elements
Transposable elements (TEs) are a major component of all genomes, thus the epigenetic mechanisms controlling their activity is an important field of study.
Beery Yaakov, Khalil Kashkush
doaj +3 more sources
Sex and the TEs: transposable elements in sexual development and function in animals
Transposable elements are endogenous DNA sequences able to integrate into and multiply within genomes. They constitute a major source of genetic innovations, as they can not only rearrange genomes but also spread ready-to-use regulatory sequences able to
Corentin Dechaud+3 more
doaj +2 more sources
Satellite DNA and Transposable Elements in Seabuckthorn (Hippophae rhamnoides), a Dioecious Plant with Small Y and Large X Chromosomes [PDF]
Seabuckthorn (Hippophae rhamnoides) is a dioecious shrub commonly used in the pharmaceutical, cosmetic, and environmental industry as a source of oil, minerals and vitamins.
Janka Puterová+8 more
semanticscholar +2 more sources
DNA on the move: mechanisms, functions and applications of transposable elements
Transposons are mobile genetic elements that have invaded all domains of life by moving between and within their host genomes. Due to their mobility (or transposition), transposons facilitate horizontal gene transfer in bacteria and foster the evolution ...
Michael Schmitz, Irma Querques
doaj +3 more sources
Whole genome resequencing reveals natural target site preferences of transposable elements in Drosophila melanogaster. [PDF]
Transposable elements are mobile DNA sequences that integrate into host genomes using diverse mechanisms with varying degrees of target site specificity.
Raquel S Linheiro, Casey M Bergman
doaj +6 more sources
Chromatin and siRNA pathways cooperate to maintain DNA methylation of small transposable elements in Arabidopsis [PDF]
BACKGROUND: DNA methylation occurs at preferred sites in eukaryotes. In Arabidopsis, DNA cytosine methylation is maintained by three subfamilies of methyltransferases with distinct substrate specificities and different modes of action.
Boyle, Tom+11 more
core +4 more sources
Transposable Elements: From DNA Parasites to Architects of Metazoan Evolution [PDF]
One of the most unexpected insights that followed from the completion of the human genome a decade ago was that more than half of our DNA is derived from transposable elements (TEs). Due to advances in high throughput sequencing technologies it is now clear that TEs comprise the largest molecular class within most metazoan genomes.
Oliver Piskurek, Daniel J. Jackson
openalex +6 more sources
Double insertion of transposable elements provides a substrate for the evolution of satellite DNA [PDF]
Eukaryotic genomes are replete with repeated sequences in the form of transposable elements (TEs) dispersed across the genome or as satellite arrays, large stretches of tandemly repeated sequences. Many satellites clearly originated as TEs, but it is unclear how mobile genetic parasites can transform into megabase-sized tandem arrays.
Michael P. McGurk, Daniel A. Barbash
openalex +6 more sources