Results 31 to 40 of about 149,433 (366)

Insertion sequence inversions mediated by ectopic recombination between terminal inverted repeats. [PDF]

PLoS ONE, 2010
Transposable elements are widely distributed and diverse in both eukaryotes and prokaryotes, as exemplified by DNA transposons. As a result, they represent a considerable source of genomic variation, for example through ectopic (i.e.
Alison Ling, Richard Cordaux
doaj   +1 more source

A beginner’s guide to manual curation of transposable elements

Mobile DNA, 2022
In the study of transposable elements (TEs), the generation of a high confidence set of consensus sequences that represent the diversity of TEs found in a given genome is a key step in the path to investigate these fascinating genomic elements.
Clément Goubert, Rory J. Craig, Agustin F. Bilat, V. Peona, Aaron A. Vogan, Anna V. Protasio   +5 more
semanticscholar   +1 more source

Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males

Nature Communications, 2020
Selfish DNA such as transposable elements cause intragenomic conflict. This study finds that on an evolutionarily young, gene-rich Drosophila Y chromosome, transposable elements evade heterochromatic suppression, leading to elevated transposition rates ...
Kevin H.-C. Wei, Lauren Gibilisco, Doris Bachtrog   +2 more
doaj   +1 more source

Role of Transposable Elements in Genome Stability: Implications for Health and Disease

International Journal of Molecular Sciences, 2022
Most living organisms have in their genome a sizable proportion of DNA sequences capable of mobilization; these sequences are commonly referred to as transposons, transposable elements (TEs), or jumping genes.
Audesh Bhat, Trupti Ghatage, Sonali Bhan, G. Lahane, A. Dhar, Rakesh Kumar, R. Pandita, K. Bhat, Kenneth S. Ramos, T. Pandita   +9 more
semanticscholar   +1 more source

Characteristics of transposable element exonization within human and mouse [PDF]

, 2010
Insertion of transposed elements within mammalian genes is thought to be an important contributor to mammalian evolution and speciation. Insertion of transposed elements into introns can lead to their activation as alternatively spliced cassette exons ...
A Athanasiadis, A Corvelo, A Gerber, A Goren, A Levy, A Magen, A Nekrutenko, A Resch, AFA Smit, Agnes Hotz-Wagenblatt, B Giardine, B Mersch, BR Graveley, Britta Mersch, C Liu, D Karolchik, D Labuda, DD Kim, E Kim, ES Lander, EY Levanon, G Ast, G Lev-Maor, G Lev-Maor, Gil Ast, H Xie, Ilya Ruvinsky, J Hull, J Jurka, J Jurka, JO Kriegs, JO Yang, JP Nemes, K Nakabayashi, KP Kister, L Lin, L Lin, M Amit, M Blow, M Krull, M Moller-Krull, M Roy, M Sironi, M Sironi, MA Batzer, MD Koob, N Gal-Mark, N Gal-Mark, N Sela, NH Gehring, Noa Sela, O Ram, P Deininger, PL Deininger, R Cordaux, R Sorek, R Sorek, R Sorek, RA Gibbs, RE Mills, RH Waterston, RM Kuhn, RT Hillman, S He, S Schwartz, SK Ng, SS Singer, ST Sherry, T Kwan, T Kwan, VV Kapitonov, W Makalowski, WJ Kent, WL Chen, WS Lo, XH Zhang, Y Xing, YF Chang   +77 more
core   +13 more sources

Transposable elements drive intron gain in diverse eukaryotes

bioRxiv, 2022
There is massive variation in intron numbers across eukaryotic genomes, yet the major drivers of intron content during evolution remain elusive. Rapid intron loss and gain in some lineages contrasts with long term evolutionary stasis in others.
Landen Gozashti, S. Roy, Bryan Thornlow, Alexander Kramer, M. Ares, Russell B. Corbett-Detig   +5 more
semanticscholar   +1 more source

Global transposable characteristics in the yeast complete DNA sequence [PDF]

, 2010
Global transposable characteristics in the complete DNA sequence of the Saccharomyces cevevisiae yeast is determined by using the metric representation and recurrence plot methods.
Wu, Zuo-Bing
core   +2 more sources

Transposable elements and circular DNAs [PDF]

Mobile Genetic Elements, 2016
Circular DNAs are extra-chromosomal fragments that become circularized by genomic recombination events. We have recently shown that yeast LTR elements generate circular DNAs through recombination events between their flanking long terminal repeats (LTRs).
openaire   +4 more sources

Modulating signaling networks by CRISPR/Cas9-mediated transposable element insertion [PDF]

, 2018
In a recent past, transposable elements (TEs) were referred to as selfish genetic components only capable of copying themselves with the aim of increasing the odds of being inherited.
A Bolotin, A Burt, A Hammond, AP Lorenzetti, B McClintock, BA Castilho, C Feschotte, C Feschotte, C Feschotte, C Kettlun, C Lu, C Ye, CN Hancock, DBT Cox, DJ Garfinkel, F Palazzoli, FA Ran, FJM Mojica, G Feng, G Mai, G Yang, H Kuang, H Mao, HT Dong, IK Jordan, J Hou, J Li, J Paszkowski, JA Doudna, JB Owens, JD Hollister, JE DiCarlo, JI Qüesta, JK Baillie, JM Casacuberta, K Kikuchi, K Naito, K Naito, K Shirasawa, KD Kim, KM Esvelt, KS Makarova, L Bortesi, L Cong, LC Li, LM Vaschetto, Luis María Vaschetto, M Cowley, M Jinek, M Momose, M Patel, M Szabo, M Turner, N Buchon, N Jiang, N Jiang, N Jiang, Q Zhang, R Barrangou, R Jansen, RM Walsh, SD Molyneux, SR Wessler, SR Yant, T Mourier, T Sakuma, T Singer, VM Gantz, W Matsunaga, WC Lai, X Li, X Li, X Lin, X Shan, Y Ishino, Y Yan, ZN Adelman   +76 more
core   +1 more source

Dnmt1 has de novo activity targeted to transposable elements

Nature Structural & Molecular Biology, 2021
DNA methylation plays a critical role during development, particularly in repressing retrotransposons. The mammalian methylation landscape is dependent on the combined activities of the canonical maintenance enzyme Dnmt1 and the de novo Dnmts, 3a and 3b.
Chuck Haggerty, H. Kretzmer, Christina Riemenschneider, Abhishek Sampath Kumar, Alexandra L. Mattei, Nina Bailly, Judith Gottfreund, Pay Giesselmann, Raha Weigert, Björn Brändl, Pascal Giehr, René Buschow, Christina Galonska, Ferdinand von Meyenn, M. Pappalardi, M. T. McCabe, L. Wittler, C. Giesecke-Thiel, T. Mielke, D. Meierhofer, B. Timmermann, F. Müller, J. Walter, A. Meissner   +23 more
semanticscholar   +1 more source