Locus-specific expression of transposable elements in single cells with CELLO-seq
Nature Biotechnology, 2021 Transposable elements (TEs) regulate diverse biological processes, from early development to cancer. Expression of young TEs is difficult to measure with next-generation, single-cell sequencing technologies because their highly repetitive nature means ...
Rebecca V Berrens +11 more
semanticscholar +1 more source
Dynamics of transposable elements generates structure and symmetries in genetic sequences [PDF]
Phys. Rev. Research 2, 033477 (2020), 2020 Genetic sequences are known to possess non-trivial composition together with symmetries in the frequencies of their components. Recently, it has been shown that symmetry and structure are hierarchically intertwined in DNA, suggesting a common origin for both features. However, the mechanism leading to this relationship is unknown. Here we investigate a
arxiv +1 more source
The epiallelic potential of transposable elements and its evolutionary significance in plants
Philosophical Transactions of the Royal Society of London. Biological Sciences, 2021 DNA provides the fundamental framework for heritability, yet heritable trait variation need not be completely ‘hard-wired’ into the DNA sequence. In plants, the epigenetic machinery that controls transposable element (TE) activity, and which includes DNA
P. Baduel, V. Colot
semanticscholar +1 more source
Genomic organization of H2Av containing nucleosomes in Drosophila heterochromatin. [PDF]
PLoS ONE, 2011 H2Av is a versatile histone variant that plays both positive and negative roles in transcription, DNA repair, and chromatin structure in Drosophila.
Zhenhai Zhang, B Franklin Pugh
doaj +1 more source
Somatically heritable switches in the DNA modification of Mu transposable elements monitored with a suppressible mutant in maize [PDF]
, 1990 Many transposable elements in maize alternate between active and inactive phases associated with the modification of their DNA. Elements in an inactive phase lose their ability to transpose, their ability to excise from reporter alleles and, in some ...
Barkan, A. +3 more
core +1 more source
Transposable elements as new players in neurodegenerative diseases
FEBS Letters, 2021 Neurodegenerative diseases (NDs), including the most prevalent Alzheimer’s disease and Parkinson disease, share common pathological features. Despite decades of gene‐centric approaches, the molecular mechanisms underlying these diseases remain widely ...
Camille Ravel-Godreuil +4 more
semanticscholar +1 more source
The biology and potential for genetic research of transposable elements in filamentous fungi
Genetics and Molecular Biology, 2005 Recently many transposable elements have been identified and characterized in filamentous fungi, especially in species of agricultural, biotechnological and medical interest.
Léia Cecilia de Lima Fávaro +3 more
doaj +1 more source
Perspective for Studying the Relationship of miRNAs with Transposable Elements
Current Issues in Molecular Biology, 2023 Transposable elements are important sources of miRNA, long non-coding RNAs genes, and their targets in the composition of protein-coding genes in plants and animals.
Rustam Nailevich Mustafin +1 more
doaj +1 more source
Nucleotide sequence of the transposable DNA-element IS2
Nucleic Acids Research, 1979 The complete sequence of the transposable DNA element IS2 in gal OP-308:: IS2 (I) has been determined. This element is 1.327 bp long. The integrated element is flanked by a five base pair long sequence duplication. The termini of IS2 are not perfect inverted repeats, but a close approximation.
H. Sommer +2 more
openaire +4 more sources
Transposable Elements as a Source of Novel Repetitive DNA in the Eukaryote Genome
Cells, 2022 The impact of transposable elements (TEs) on the evolution of the eukaryote genome has been observed in a number of biological processes, such as the recruitment of the host’s gene expression network or the rearrangement of genome structure. However, TEs may also provide a substrate for the emergence of novel repetitive elements, which contribute to ...
Michelle Louise Zattera +1 more
openaire +3 more sources