Results 61 to 70 of about 167,159 (369)
Transposable elements as new players in neurodegenerative diseases
FEBS Letters, 2021 Neurodegenerative diseases (NDs), including the most prevalent Alzheimer’s disease and Parkinson disease, share common pathological features. Despite decades of gene‐centric approaches, the molecular mechanisms underlying these diseases remain widely ...
Camille Ravel-Godreuil +4 more
semanticscholar +1 more source
DNA rearrangements associated with a transposable element in yeast
Cell, 1980 The his4-912 mutation results from insertion of a 6200 bp transposable element into the his4 gene of yeast. In order to clone the his4-912 mutation, the plasmid pBR322 was integrated into the his4 gene by means of yeast transformation, and then the vector sequences and the his4-912 insertion element were excised as a single restriction fragment.
G S, Roeder, G R, Fink
openaire +2 more sources
TranspoGene and microTranspoGene: transposed elements influence on the transcriptome of seven vertebrates and invertebrates [PDF]
, 2008 Transposed elements (TEs) are mobile genetic sequences. During the evolution of eukaryotes TEs were inserted into active protein-coding genes, affecting gene structure, expression and splicing patterns, and protein sequences.
Asaf Levy +43 more
core +3 more sources
The epiallelic potential of transposable elements and its evolutionary significance in plants
Philosophical Transactions of the Royal Society of London. Biological Sciences, 2021 DNA provides the fundamental framework for heritability, yet heritable trait variation need not be completely ‘hard-wired’ into the DNA sequence. In plants, the epigenetic machinery that controls transposable element (TE) activity, and which includes DNA
P. Baduel, V. Colot
semanticscholar +1 more source
Transposon variants and their effects on gene expression in arabidopsis [PDF]
, 2013 Transposable elements (TEs) make up the majority of many plant genomes. Their transcription and transposition is controlled through siRNAs and epigenetic marks including DNA methylation.
Smith, L.M., Wang, X., Weigel, D.
core +3 more sources
A Field Guide to Eukaryotic Transposable Elements.
Annual Review of Genetics, 2020 Transposable elements (TEs) are mobile DNA sequences that propagate within genomes. Through diverse invasion strategies, TEs have come to occupy a substantial fraction of nearly all eukaryotic genomes, and they represent a major source of genetic ...
J. Wells, C. Feschotte
semanticscholar +1 more source
Genome Biology, 2016 BackgroundChromatin modifications such as DNA methylation are targeted to transposable elements by small RNAs in a process termed RNA-directed DNA methylation (RdDM). In plants, canonical RdDM functions through RNA polymerase IV to reinforce pre-existing
Kaushik Panda +5 more
semanticscholar +1 more source
Molecular biology and evolutionAlthough both are salient features of genomes, at first glance ribosomal DNAs and transposable elements are genetic elements with not much in common: whereas ribosomal DNAs are mainly viewed as housekeeping genes that uphold all prime genome functions ...
Sònia Garcia +8 more
semanticscholar +1 more source
Communications Biology, 2021 Ba Van Vu, Quyet Nguyen et al. investigate the mechanism by which transposable elements are targeted for DNA methylation, using the fungus Pyricularia oryzae as a model system.
Ba Van Vu +8 more
doaj +1 more source
Double insertion of transposable elements provides a substrate for the evolution of satellite DNA
bioRxiv, 2017 Eukaryotic genomes are replete with repeated sequences, in the form of transposable elements (TEs) dispersed across the genome or as satellite arrays, large stretches of tandemly repeated sequence.
Michael P. McGurk, D. Barbash
semanticscholar +1 more source