Results 71 to 80 of about 93,119 (340)

Synergistic All‐in‐One Electroceutical Platform Utilizing a Plasma–Photodynamic Hybrid Approach for Enhanced Wound Healing

Advanced Functional Materials, EarlyView.
A flexible hybrid patch integrating a robust cold atmospheric plasma (CAP) system with a high‐power, ultrathin bio‐OLED was developed to enable synergistic wound healing. This multimodal therapy, combining plasma and photodynamic treatment, enhanced angiogenesis, cell proliferation, and collagen deposition, demonstrating superior in vivo efficacy and ...
Jun‐Yeop Song, Hyun Cheol Bang, Young Hyun Son, Dae‐In Ha, Eun‐Ju Hong, Sun‐Woo Lee, Jeongsook Kim, Doyeong Kim, Sang‐Min Park, Kyu Pil Lee, Hyo‐Jung Kwon, Jeong Hyun Kwon   +11 more
wiley   +1 more source

Insecticide exposure affects intergenerational patterns of DNA methylation in the Colorado potato beetle, Leptinotarsa decemlineata

Evolutionary Applications, 2021
Insecticide use is pervasive as a selective force in modern agroecosystems. Insect herbivores exposed to these insecticides have been able to rapidly evolve resistance to them, but how they are able to do so is poorly understood. One possible but largely
Kristian Brevik, Erika M. Bueno, Stephanie McKay, Sean D. Schoville, Yolanda H. Chen   +4 more
doaj   +1 more source

Dynamic Patterns of Transcript Abundance of Transposable Element Families in Maize. [PDF]

, 2019
Transposable Elements (TEs) are mobile elements that contribute the majority of DNA sequences in the maize genome. Due to their repetitive nature, genomic studies of TEs are complicated by the difficulty of properly attributing multi-mapped short reads ...
Anderson, Sarah N, Hirsch, Cory D, Ross-Ibarra, Jeffrey, Springer, Nathan M, Stitzer, Michelle C, Zhou, Peng   +5 more
core  

The 5' untranslated region of the I factor, a long interspersed nuclear element-like retrotransposon of Drosophila melanogaster, contains an internal promoter and sequences that regulate expression [PDF]

, 1993
The I-R system of hybrid dysgenesis in Drosophila melanogaster is controlled by a long interspersed nuclear element-like retroposon, the I factor.
BUCHETON, A, FINNEGAN, D J, Finnegan, David, MCLEAN, C   +3 more
core   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

The CCCTC-binding factor (CTCF) of Drosophila contributes to the regulation of the ribosomal DNA and nucleolar stability. [PDF]

PLoS ONE, 2011
In the repeat array of ribosomal DNA (rDNA), only about half of the genes are actively transcribed while the others are silenced. In arthropods, transposable elements interrupt a subset of genes, often inactivating transcription of those genes. Little is
Paola A Guerrero, Keith A Maggert
doaj   +1 more source

Reduced mutation rate and increased transformability of transposon-free Acinetobacter baylyi ADP1-ISx [PDF]

, 2017
The genomes of most bacteria contain mobile DNA elements that can contribute to undesirable genetic instability in engineered cells. In particular, transposable insertion sequence (IS) elements can rapidly inactivate genes that are important for a ...
Barrick, Jeffrey E, Dasgupta, Aurko, Renda, Brian A, Suárez, Gabriel A   +3 more
core   +2 more sources

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Analyses of methylomes of upland and lowland switchgrass (Panicum virgatum) ecotypes using MeDIP-seq and BS-seq

BMC Genomics, 2017
Background Switchgrass is a crop with many desirable traits for bioenergy production. Plant genomes have high DNA methylation levels throughout genes and transposable elements and DNA methylation is known to play a role in silencing transposable elements.
Mollee Dworkin, Shaojun Xie, Malay Saha, Jyothi Thimmapuram, Venu (Kal) Kalavacharla   +4 more
doaj   +1 more source

Diversification of the Caenorhabditis heat shock response by Helitron transposable elements. [PDF]

, 2019
Heat Shock Factor 1 (HSF-1) is a key regulator of the heat shock response (HSR). Upon heat shock, HSF-1 binds well-conserved motifs, called Heat Shock Elements (HSEs), and drives expression of genes important for cellular protection during this stress ...
Ahringer, Altschul, Ashe, Bailey, Bourque, Brunquell, Casper, Cavrak, Christians, Chuong, Chuong, Contrino, Cook, Cook, Cutter, Esnault, Feschotte, Fierst, Fuentes, Gonsalves, Grabundzija, Grant, Guertin, Gupta, Halfon, Ho, Howe, Howe, Huang, Huang, Hubley, Ito, Jedlicka, Jiang, Johnstone, Jordan, Kanzaki, Kapitonov, Kapitonov, Kent, Kojima, Labbadia, Langmead, Lee, Li, Li, Li, Liu, Love, Mahat, Maman, Mao, Mark, Matys, McClintock, Mendillo, Mortazavi, Narasimhan, Narasimhan, Patro, Perisic, Pontis, R Development Core Team, Rausch, Santos, Schreiner, Shirayama, Slos, Slotkin, Solís, Stevens, Sun, Sundaram, Sundaram, Tajima, Takaki, Thomas, Thomas, Thomas, Todd, Verster, Vihervaara, Weirauch, Wood, Zhang   +84 more
core   +2 more sources