Results 241 to 250 of about 121,903 (271)
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Use of transposon-promoted deletions in DNA sequence analysis
Journal of Molecular Biology, 1984The usefulness of the dideoxy method for DNA sequencing can be greatly extended by the use of transposon-generated deletions. These deletions have the unique property of extending from a fixed nucleotide at the transposon terminus to various sites outside it.
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Methods in molecular biology (Clifton, N.J.), 2008
Understanding the genetic basis for tumor formation is crucial for treating cancer. Forward genetic screens using insertional mutagenesis technologies have identified many important tumor suppressor genes and oncogenes in mouse models of human cancer. Traditionally, retroviruses have been used for this purpose, allowing the identification of genes that
David A, Largaespada, Lara S, Collier
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Understanding the genetic basis for tumor formation is crucial for treating cancer. Forward genetic screens using insertional mutagenesis technologies have identified many important tumor suppressor genes and oncogenes in mouse models of human cancer. Traditionally, retroviruses have been used for this purpose, allowing the identification of genes that
David A, Largaespada, Lara S, Collier
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Circulating tumor DNA in advanced solid tumors: Clinical relevance and future directions
Ca-A Cancer Journal for Clinicians, 2021Michael L Cheng +2 more
exaly
Transposon-associated TnpB is a programmable RNA-guided DNA endonuclease
Nature, 2021Tautvydas Karvelis +2 more
exaly
DNA repair | Nonhomologous Recombination: Bacterial Transposons
2021Catherine Guynet +3 more
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Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector
Cell, 2023Shukun Wang, Thomas Klose, Leifu Chang
exaly
Target site selection and remodelling by type V CRISPR-transposon systems
Nature, 2021Irma Querques +2 more
exaly
DNA Integrating Vectors (Transposon, Integrase)
2010Lauren E. Woodard, Michele P. Calos
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Structural basis for the assembly of the type V CRISPR-associated transposon complex
Cell, 2022Michael Schmitz +2 more
exaly