Results 31 to 40 of about 3,025,811 (189)

An Overview of DNA Vaccines Development Studies Against Toxoplasma gondii

open access: yesTürkiye Parazitoloji Dergisi, 2022
Toxoplasma gondii (T. gondii) is an obligate intracellular parasite that can infect almost all warm-blooded animals, including humans, and one-third of the global population is thought to be infected with this parasite.
Ceren Gül   +9 more
doaj   +1 more source

DNA vaccines and recombinant allergens with reduced allergenic activity treat allergies

open access: yesRussian Open Medical Journal, 2021
This review is intended to familiarize readers with major novel directions of developing allergy vaccines, their structure, as well as the mechanisms of forming a new immunological response in the course of the treating immunoglobulin E (IgE)-mediated ...
Stanislava Yu. Petrova   +4 more
doaj   +1 more source

Responsiveness to basement membrane extract as a possible trait for tumorigenicity characterization

open access: yesVaccine: X, 2019
Immortalized cell lines used to produce vaccines are expected to be described in terms of their tumorigenicity. However, current in vivo tumorigenicity assays can be time-consuming and results can be equivocal, especially for weakly tumorigenic cells ...
Haruhiko Murata   +7 more
doaj   +1 more source

Allergy vaccines for specific immunotherapy

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2021
Allergen-specific immunotherapy (ASIT) has been used for more than a hundred years to treat patients with IgEmediated allergic diseases. The most common allergens have been obtained using molecular cloning technology in the past two decades.
S. Yu. Petrova   +3 more
doaj   +1 more source

Synthetic DNA Vaccines Adjuvanted with pIL-33 Drive Liver-Localized T Cells and Provide Protection from Plasmodium Challenge in a Mouse Model

open access: yesVaccines, 2020
The need for a malaria vaccine is indisputable. A single vaccine for Plasmodium pre-erythrocytic stages targeting the major sporozoite antigen circumsporozoite protein (CSP) has had partial success.
Sophia M. Reeder   +14 more
doaj   +1 more source

Genetic (DNA) Vaccines

open access: yesПроблемы особо опасных инфекций, 2010
With the development of various branches of medicine and biology the classical ideas about means to prevent infectious diseases have changed. Nowadays in different countries of the world, investigations are carried out intensively in the sphere of ...
Yu. A. Popov, N. I. Mikshis
doaj   +1 more source

An update on Zika vaccine developments

open access: yesExpert Review of Vaccines, 2017
Introduction: The devastating consequences of congenital Zika virus (ZIKV) infection led to a global response directed toward a better understanding of the epidemiology and pathogenesis of ZIKV and to efforts at vaccine development.
Anna Durbin, Annelies Wilder-Smith
doaj   +1 more source

DENV-3 precursor membrane (prM) glycoprotein enhances E protein immunogenicity and confers protection against DENV-2 infections in a murine model

open access: yesHuman Vaccines & Immunotherapeutics, 2021
To improve a DNA vaccine containing the truncated dengue virus serotype 2 (DENV-2) envelope (E) protein and evaluate the influence of precursor membrane (prM) glycoprotein polymorphism on E protein immunogenicity, two vaccine candidates have been ...
Roberto S. Dias   +7 more
doaj   +1 more source

Vaccination-induced skin-resident memory CD8+ T cells mediate strong protection against cutaneous melanoma

open access: yesOncoImmunology, 2018
Memory CD8+ T cell responses have the potential to mediate long-lasting protection against cancers. Resident memory CD8+ T (Trm) cells stably reside in non-lymphoid tissues and mediate superior innate and adaptive immunity against pathogens.
Felipe Gálvez-Cancino   +13 more
doaj   +1 more source

DNA Vaccines—How Far From Clinical Use?

open access: yesInternational Journal of Molecular Sciences, 2018
Two decades ago successful transfection of antigen presenting cells (APC) in vivo was demonstrated which resulted in the induction of primary adaptive immune responses.
Dominika Hobernik, Matthias Bros
semanticscholar   +1 more source

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