Results 71 to 80 of about 613,851 (307)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The Multifarious Role of 14-3-3 Family of Proteins in Viral Replication
Viruses, 2020 The 14-3-3 proteins are a family of ubiquitous and exclusively eukaryotic proteins with an astoundingly significant number of binding partners. Their binding alters the activity, stability, localization, and phosphorylation state of a target protein. The
Kavitha Ganesan Nathan, Sunil K. Lal
doaj +1 more source
Viral microRNA effects on persistent infection of human lymphoid cells by polyomavirus SV40. [PDF]
PLoS ONE, 2018 Polyomaviruses, including simian virus 40 (SV40), display evidence of lymphotropic properties. This study analyzed the nature of SV40-human lymphocyte interactions in established cell lines and in primary lymphocytes.
Adrienne L McNees +5 more
doaj +1 more source
Optimal number of spacers in CRISPR arrays
, 2017 We estimate the number of spacers in a CRISPR array of a bacterium which maximizes its protection against a viral attack. The optimality follows from a competition between two trends: too few distinct spacers make the bacteria vulnerable to an attack by ...
Ispolatov, Yaroslav +2 more
core +1 more source
Human adenoviruses role in ophthalmic pterygium formation [PDF]
, 2015 Background: Ophthalmic pterygium is a common benign lesion of unknown origin and the pathogenesis might be vision-threatening. This problem is often associated with exposure to solar light. Recent evidence suggests that potentially oncogenic viruses such
Bazouri, M. +5 more
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Immune Response to Herpes Simplex Virus Infection and Vaccine Development
Vaccines, 2020 Herpes simplex virus (HSV) infections are among the most common viral infections and usually last for a lifetime. The virus can potentially be controlled with vaccines since humans are the only known host.
Anthony C. Ike +4 more
doaj +1 more source
Successful Treatment of Severe Adenoviral ARDS Using Cidofovir in a Case with Cerebral Palsy
Journal of Pediatric Emergency and Intensive Care Medicine, 2021 Adenovirus is a non-enveloped, double-stranded DNA virus that can cause infections in the upper and lower respiratory tract, conjunctiva, and gastrointestinal tract. Adenovirus infections are usually mild but may cause mortality and morbidity, especially
Emrah Gün +7 more
doaj +1 more source
Nucleotide bias of DCL and AGO in plant anti-virus gene silencing [PDF]
, 2010 Plant Dicer-like (DCL) and Argonaute (AGO) are the key enzymes involved in anti-virus post-transcriptional gene silencing (AV-PTGS). Here we show that AV-PTGS exhibited nucleotide preference by calculating a relative AV-PTGS efficiency on processing ...
Dalmay, Tamas +8 more
core +1 more source
Infectivity of Molecular Forms of Simian Virus 40 DNA
Journal of General Virology, 1971 Summary The conversion of superhelical (Form I) SV40 DNA to nicked molecular forms was studied by incubating SV40 [3H]DNA for ½ to 2 hr with monolayer cultures of monkey, human, or mouse cells in the presence of DEAE-dextran. The superhelical and the nicked DNA forms were then extracted from the cultures and separated by equilibrium centrifugation in ...
D, Trkula +3 more
openaire +2 more sources