Results 31 to 40 of about 8,074 (224)
Applications of Graphene Quantum Dots in Biomedical Sensors [PDF]
, 2020 Due to the proliferative cancer rates, cardiovascular diseases, neurodegenerative disorders, autoimmune diseases and a plethora of infections across the globe, it is essential to introduce strategies that can rapidly and specifically detect the ultralow ...
Altintas, Zeynep, Mansuriya, Bhargav D.
core +1 more source
DNAzyme Footprinting: Detecting Protein–Aptamer Complexation on Surfaces by Blocking DNAzyme Cleavage Activity [PDF]
Journal of the American Chemical Society, 2013 A novel method to quantitatively measure the binding of proteins to single-stranded DNA (ssDNA) aptamers that employs the inhibition of the DNAzyme hydrolysis of aptamer monolayers is described. A 28-base DNAzyme was designed to specifically bind to and cleave a 29-base ssDNA sequence that can fold into a G-quartet aptamer and bind the protein thrombin.
Yulin, Chen, Robert M, Corn
openaire +2 more sources
Biomolecules, 2021 Numerical computation is a focus of DNA computing, and matrix operations are among the most basic and frequently used operations in numerical computation.
Shaoxia Xu +4 more
doaj +1 more source
Sensing Parts-per-Trillion Cd2+, Hg2+ and Pb2+ Collectively and Individually Using Phosphorothioate DNAzymes [PDF]
, 2014 This document is the Accepted Manuscript version of a Published Work that appeared in final form in Analytical Chemistry, copyright © American Chemical Society after peer review and technical editing by publisher. To access the final edited and published
Huang, Po-Jung Jimmy, Liu, Juewen
core +1 more source
Increasing the activity of DNAzyme based on the telomeric sequence: 2’-OMe-RNA and LNA modifications
Open Chemistry, 2019 2’-OMe-RNA analogues and LNA point modifications of DNA oligonucleotides were applied for the modulation of the G-quadruplex topology and enhancement of peroxidase activity of the resulting DNAzymes.
Kosman J., Żukowski K., Juskowiak B.
doaj +1 more source
Voltammetry and Molecular Assembly of G-quadruplex DNAzyme on Single-crystal Au(111)-electrode Surfaces – Hemin as an Electrochemical Intercalator [PDF]
, 2016 DNA quadruplexes (qs) are a class of “non-canonical” oligonucleotides (OGNs) composed of stacked guanine (G) quartets stabilized by specific cations. Metal porphyrins selectively bind to G-qs complexes to form what is known as DNAzyme, which can exhibit ...
Ulstrup, Jens +2 more
core +1 more source
Reviews in Analytical Chemistry, 2021 Sensitive DNA assays are of importance in life science and biomedical engineering, but they are heavily dependent on thermal cycling programs or enzyme-assisted schemes, which require the utilization of bulky devices and costly reagents.
Iwe Idorenyin, Li Zhigang
doaj +1 more source
A Cleavable Molecular Beacon for Hg2+ Detection based on Phosphorothioate RNA Modifications [PDF]
, 2015 This document is the Accepted Manuscript version of a Published Work that appeared in final form in Analytical Chemistry copyright © American Chemical Society after peer review and technical editing by publisher.
Huang, Po-Jung Jimmy +2 more
core +1 more source
Angewandte Chemie, EarlyView.Current interest in artificial cell research underscores its potential to deepen our understanding of life's fundamental processes. This review highlights advances in bottom‐up coacervate‐based artificial cell engineering via combined integration of cellular hallmarks.
Arjan Hazegh Nikroo +3 more
wiley +2 more sources
Photoactivated Signaling Networks using DNA‐Based Synthetic Organelles as Biomimetic Protocells
Angewandte Chemie, EarlyView.Light‐triggered intercommunication between two types of organelle‐loaded liposomes lead to DNAzyme‐mediated on transcription‐guided structural reconfiguration of the organelles. ABSTRACT Membraneless organelles formed by phase‐separated nucleic acid or protein condensates play vital roles in regulating cellular functions.
Huiying Xue +6 more
wiley +2 more sources