Label-free detection of Cu(2+) and Hg(2+) ions using reconstructed Cu(2+)-specific DNAzyme and G-quadruplex DNAzyme. [PDF]
Label-free metal ion detection methods were developed. To achieve these, a reconstructed Cu(2+)-specific DNA-cleaving DNAzyme (Cu(2+)-specific DNAzyme) with an intramolecular stem-loop structure was used.
Hui Li +5 more
doaj +1 more source
Recent applications on the combination of Mesoporous Silica Nanoparticles with Nucleic Acids: Development of Bioresponsive Devices, Carriers and Sensors [PDF]
The discovery and control of the biological roles mediated by nucleic acids have turned them into a powerful tool for the development of advanced biotechnological materials.
Baeza, Alejandro +2 more
core +2 more sources
On-site detection of fish furunculosis by combining DNAzyme and carboxyl-functionalized graphene
Furunculosis, which is caused by Aeromonas salmonicida, can induce septicemia, leading to the rapid death of fishes belonging to Salmonidae, Cyprinidae, and Fuscheridae, and lamprey. Targeting A.
Wen Ding +13 more
doaj +1 more source
Tandem Phosphorothioate Modifications for DNA Adsorption Strength and Polarity Control on Gold Nanoparticles [PDF]
This document is the Accepted Manuscript version of a Published Work that appeared in final form in Applied Materials & Interfaces, copyright © American Chemical Society after peer review and technical editing by publisher. To access the final edited and
Wenhu Zhou +45 more
core +3 more sources
Conventional unipedal DNA walkers suffer from several limitations of low efficiency. In contrast, multipedal DNA walkers, which often operate freely beyond the loading surface, may exhibit reduced amplification efficiency due to uncontrolled movement. To
Ye Tian +7 more
doaj +1 more source
Aptamer based electrochemical sensors for emerging environmental pollutants [PDF]
International audienceEnvironmental contaminants monitoring is one of the key issues in understanding and managing hazards to human health and ecosystems.
Akhtar Hayat, Jean L. Marty
core +2 more sources
Mechanozyme: An Artificial Enzyme With a Mechanophore Framework
Mechanical destabilization of a G‐quadruplex mechanophore in a DNAzyme markedly boosts its catalytic activity, demonstrating “mechanozymes” as artificial enzymes whose functions are modulated by mechanical stress exerted by ultrasonication. This mechanozyme principle is broadly applicable to control biomolecular activities.
Jiahao Ji +7 more
wiley +1 more source
Visual detection of lead(II) using a label-free DNA-based sensor and its immobilization within a monolithic hydrogel [PDF]
Lead is highly toxic and its detection has attracted a lot of research interests. In recent years, DNA has been used for Pb2+ recognition and many fluorescent sensors with low to sub-nM detection limits have been reported.
Jacobi, Zachary E., Li, Lu, Liu, Juewen
core +1 more source
A catalytic allosteric DNAzyme assay (SMART) is developed by engineering DNAzyme into a unimolecular biosensor, enabling highly sensitive and multiplex detection of small molecules and nucleic acids. SMART enables extraction‐free, one‐pot, one‐step, isothermal, and cost‐effective detection of biological markers, achieving >95% accuracy for rapid ...
Yanzhe Shen +12 more
wiley +1 more source
Target recycling product-bridged DNAzyme walker for sensitive detection of microRNA
The precise and sensitive detection of miRNA is significant for assessing infectious illnesses, particularly pneumonia. However, constrained by the low abundance of miRNA in samples, the majority of miRNA detection approaches employing a one-to-one ...
Ning Pan +5 more
doaj +1 more source

