Results 101 to 110 of about 94,936 (269)

Current Advances of Treatments, Therapeutic Targets, Biomarkers, Novel Drugs, and Machine Learning for Hypopharyngeal Squamous Cell Carcinoma

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li   +12 more
wiley   +1 more source

Hemorrhagic Cystitis in a Patient Receiving Docetaxel for Prostate Cancer

open access: yesClinical Medicine Insights: Oncology, 2010
A case is reported in which docetaxel was used to treat a patient with hormone refractory metastatic prostate cancer. The treatment was terminated at the third course of docetaxel following the development of hemorrhagic cystitis.
A.I. Ntekim, A. Ajekigbe
doaj   +1 more source

Palbociclib in the Treatment of HR+/ HER2‐ Advanced or Metastatic Breast Cancer in Australia: A Real‐World Retrospective Analysis

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
This study investigated the real‐world use of CDK4/6 inhibitors in Australian patients with HR+/HER2‐ advanced or metastatic breast cancer, providing data on patient demographics, treatment patterns, and outcomes with palbociclib. ABSTRACT Background There is limited real‐world data on the use of CDK4/6 inhibitors in Australian patients with HR+/HER2 ...
Louise Nott   +8 more
wiley   +1 more source

Systemic Therapy Management Strategies for Early‐Stage Breast Cancer in Australia

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
Advances in systemic therapy for early‐stage breast cancer in Australia highlight genomic‐guided decisions, subtype‐specific strategies, and emerging targeted and immunotherapies, shaping personalized and de‐escalated treatment approaches. ABSTRACT Breast cancer is the most common cancer among Australian women, with early‐stage disease (Stages I, II ...
Nicholas Zdenkowski   +6 more
wiley   +1 more source

Intravenous microemulsion of docetaxel containing an anti-tumor synergistic ingredient (Brucea javanica oil): formulation and pharmacokinetics

open access: yes, 2013
Shilin Ma,1 Fen Chen,1 Xiaohui Ye,2 Yingjie Dong,2 Yingna Xue,1 Heming Xu,1 Wenji Zhang,1 Shuangshuang Song,1 Li Ai,2 Naixian Zhang,2 Weisan Pan1 1School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 2Liaoning Institute of Pharmaceutical ...
Zhang W   +10 more
core  

Updated EAACI Statement on Drug Hypersensitivity Skin Testing: Methodology and Non‐Irritative Concentrations

open access: yesAllergy, EarlyView.
ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud   +14 more
wiley   +1 more source

A phase I study of docetaxel plus synthetic lycopene in metastatic prostate cancer patients

open access: yesClinical and Translational Medicine
Purpose Our preclinical studies showed that lycopene enhanced the anti‐prostate cancer efficacy of docetaxel in animal models. A phase I trial (NCT0149519) was conducted to identify an optimum dose of synthetic lycopene in combination with docetaxel (and
Michael B. Lilly   +11 more
doaj   +1 more source

A novel lipid-based nanomicelle of docetaxel: evaluation of antitumor activity and biodistribution

open access: yes, 2012
Mingshu Ma,1 Yanli Hao,1 Nan Liu,1 Zhe Yin,1 Lan Wang,1 Xingjie Liang,2 Xiaoning Zhang11Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing, China; 2National Center for Nanoscience and Technology ...
Ma M   +6 more
core  

Roux‐en‐Y Reconstruction After Esophagectomy for Postoperative Functional Complaints: A Case Series

open access: yesANZ Journal of Surgery, EarlyView.
Functional complaints affect half of esophagectomy patients, with no standard treatment. In nine patients, Roux‐en‐Y reconstruction for obstruction, redundant conduit, and weight loss was safely performed, with one major complication and no Grade 4 out of five events. Complete symptom resolution reached 67% at 3 months and 89% at 1 year.
Donika Zogaj   +6 more
wiley   +1 more source

Mannan-modified Ad5-PTEN treatment combined with docetaxel improves the therapeutic effect in H22 tumor-bearing mice

open access: yes, 2012
Zhongbing Liu, Jinwei Li, Juan Li, Juan Huang, Famin Ke, Qiaona Qi, Xing Jiang, Zhirong ZhongLuzhou Medical College, Luzhou, Sichuan, People's Republic of ChinaBackground: It has been reported that the tumor suppressor gene, PTEN, which is ...
Liu Z   +6 more
core  

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