Results 111 to 120 of about 89,572 (287)

"Docetaxel in adjuvant therapy of breast cancer: results of the TAXIT 216 multicenter trial"

open access: yes, 2008
The dissertation is focused on the evaluation of a Docetaxel-based sequential regimen as adjuvant therapy of breast cancer. Docetaxel is among the most active chemotherapeutic agents for breast cancer.
Forestieri, Valeria
core  

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

open access: yesPrecision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

A novel lipid-based nanomicelle of docetaxel: evaluation of antitumor activity and biodistribution

open access: yes, 2012
Mingshu Ma,1 Yanli Hao,1 Nan Liu,1 Zhe Yin,1 Lan Wang,1 Xingjie Liang,2 Xiaoning Zhang11Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing, China; 2National Center for Nanoscience and Technology ...
Ma M   +6 more
core  

Time to full publication of studies of anti-cancer medicines for breast cancer, and the potential for publication bias: a short systematic review

open access: yes, 2008
Objectives: To identify the expected delay between publication of conference abstracts and full publication of results from trials of new anti-cancer agents for breast cancer and to identify whether there are any apparent biases in publication and ...
Hartwell, D.   +9 more
core   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

open access: yesPrecision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang   +7 more
wiley   +1 more source

Intravenous microemulsion of docetaxel containing an anti-tumor synergistic ingredient (Brucea javanica oil): formulation and pharmacokinetics

open access: yes, 2013
Shilin Ma,1 Fen Chen,1 Xiaohui Ye,2 Yingjie Dong,2 Yingna Xue,1 Heming Xu,1 Wenji Zhang,1 Shuangshuang Song,1 Li Ai,2 Naixian Zhang,2 Weisan Pan1 1School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 2Liaoning Institute of Pharmaceutical ...
Zhang W   +10 more
core  

Alternative drug formulations of docetaxel: a review

open access: yes, 2007
The anticancer drug docetaxel (Taxotere) is formulated in the nonionic surfactant polysorbate 80 (Tween 80). Early in the clinical development of docetaxel, it became clear that docetaxel administration is associated with the occurrence of unpredictable (
Engels, Frederike   +4 more
core   +1 more source

Efficacy, Safety, and Cost‐Effectiveness of Reduced versus Full Initial Doses of Androgen Receptor Signaling Inhibitors in Non‐Metastatic Castration‐Resistant Prostate Cancer: A Multicenter Retrospective Study

open access: yesThe Prostate, EarlyView.
ABSTRACT Background The introduction of novel androgen receptor signaling inhibitors (ARSIs) has substantially transformed the systemic treatment landscape for non‐metastatic castration‐resistant prostate cancer (nmCRPC). Unfortunately, ARSI therapy is associated with considerable adverse events (AEs) and high medical costs.
Himawari Asanuma   +18 more
wiley   +1 more source

Sequence-dependent Effect of Docetaxel with Gefitinib on the Proliferation and Signal Protein Expression of Human Lung Adenocarcinoma Cell SPC-A1

open access: yesChinese Journal of Lung Cancer, 2011
Background and objective It has been proven that chemotherapy combined with epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) could not increase response for advanced non-small cell lung cancer (NSCLC), but its cellular mechanism ...
Feng XIAO   +4 more
doaj   +1 more source

Mannan-modified Ad5-PTEN treatment combined with docetaxel improves the therapeutic effect in H22 tumor-bearing mice

open access: yes, 2012
Zhongbing Liu, Jinwei Li, Juan Li, Juan Huang, Famin Ke, Qiaona Qi, Xing Jiang, Zhirong ZhongLuzhou Medical College, Luzhou, Sichuan, People's Republic of ChinaBackground: It has been reported that the tumor suppressor gene, PTEN, which is ...
Liu Z   +6 more
core  

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