Results 71 to 80 of about 1,575 (172)

Bacterial Outer Membrane Vesicles: From Physics to Clinical

MedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.
A review of an introduction to the mechanisms of formation of OMVs, their action on bacteria and relationship to disease, vaccines, biomonitoring, drug delivery and regenerative medicine in the clinic. ABSTRACT Bacterial outer membrane vesicles (OMVs) are nanoscale vesicular structures naturally produced by Gram‐negative bacteria during growth.
Jun Zhou, Shuang Zou, Derong Dai, Liqing He, Xingyu Mou, Ninglin Zhao, Hong Li, Rui Bao   +7 more
wiley   +1 more source

Engineering the cell surface display of cohesins for assembly of cellulosome-inspired enzyme complexes on Lactococcus lactis

Microbial Cell Factories, 2010
Background The assembly and spatial organization of enzymes in naturally occurring multi-protein complexes is of paramount importance for the efficient degradation of complex polymers and biosynthesis of valuable products.
Wieczorek Andrew S, Martin Vincent JJ
doaj   +1 more source

Dockerin-like sequences in cellulases and xylanases from the rumen cellulolytic bacterium Ruminococcus flavefaciens [PDF]

FEMS Microbiology Letters, 2006
Recent analysis of the endA cellulase gene from Ruminococcus flavefaciens 17 has revealed that it encodes a product of 759 amino acids that provides the first example of a multidomain cellulase from a Ruminococcus sp. Following the family 5 catalytic domain in the predicted EndA enzyme is a 282 amino acid domain of unknown function for which no close ...
J, Kirby, J C, Martin, A S, Daniel, H J, Flint   +3 more
openaire   +2 more sources

Leveraging the Power of Enzymes in Engineered Dead and Living Materials

Advanced Functional Materials, Volume 34, Issue 44, October 29, 2024.
Insights gained during the design of functional enzyme materials have immense potential to supercharge the nascent Engineered Living Material (ELM) field. In this review, these impressive material design strategies are unpacked and contrasted with the enzyme‐control systems used by microorganisms.
Mark R. Shannon, Bini Zhou, Adam W. Perriman   +2 more
wiley   +1 more source

The Clostridium cellulolyticum Dockerin Displays a Dual Binding Mode for Its Cohesin Partner [PDF]

Journal of Biological Chemistry, 2008
The plant cell wall degrading apparatus of anaerobic bacteria includes a large multienzyme complex termed the "cellulosome." The complex assembles through the interaction of enzyme-derived dockerin modules with the multiple cohesin modules of the noncatalytic scaffolding protein.
Pinheiro BA, Proctor MR, Martinez-Fleites C, Prates JA, Money VA, Davies GJ, Bayer EA, Fontesm CM, Fierobe HP, Gilbert HJ   +9 more
openaire   +3 more sources

Crystal structure of an uncommon cellulosome-related protein module from Ruminococcus flavefaciens that resembles papain-like cysteine peptidases. [PDF]

PLoS ONE, 2013
Ruminococcus flavefaciens is one of the predominant fiber-degrading bacteria found in the rumen of herbivores. Bioinformatic analysis of the recently sequenced genome indicated that this bacterium produces one of the most intricate cellulosome systems ...
Maly Levy-Assaraf, Milana Voronov-Goldman, Inna Rozman Grinberg, Gloria Weiserman, Linda J W Shimon, Sadanari Jindou, Ilya Borovok, Bryan A White, Edward A Bayer, Raphael Lamed, Felix Frolow   +10 more
doaj   +1 more source

Cellulosome‐like sequences in Archaeoglobus fulgidus: an enigmatic vestige of cohesin and dockerin domains [PDF]

FEBS Letters, 1999
The distribution of cellulosomal cohesin domains among the sequences currently compiled in various sequence databases was investigated. Two cohesin domains were detected in two consecutive open reading frames (ORFs) of the recently sequenced genome of the archaeon Archaeoglobus fulgidus.
Bayer, Edward A., Coutinho, Pedro M., Henrissat, Bernard   +2 more
openaire   +2 more sources

Structural and molecular insights into a bifunctional glycoside hydrolase 30 xylanase specific to glucuronoxylan

Biotechnology and Bioengineering, Volume 121, Issue 7, Page 2067-2078, July 2024.
Abstract Glycoside hydrolase (GH) 30 family xylanases are enzymes of biotechnological interest due to their capacity to degrade recalcitrant hemicelluloses, such as glucuronoxylan (GX). This study focuses on a subfamily 7 GH30, TtXyn30A from Thermothelomyces thermophilus, which acts on GX in an “endo” and “exo” mode, releasing methyl‐glucuronic acid ...
Christina Pentari, Christos Kosinas, Efstratios Nikolaivits, Maria Dimarogona, Evangelos Topakas   +4 more
wiley   +1 more source

Creation of a functional hyperthermostable designer cellulosome

Biotechnology for Biofuels, 2019
Background Renewable energy has become a field of high interest over the past decade, and production of biofuels from cellulosic substrates has a particularly high potential as an alternative source of energy.
Amaranta Kahn, Sarah Moraïs, Anastasia P. Galanopoulou, Daehwan Chung, Nicholas S. Sarai, Neal Hengge, Dimitris G. Hatzinikolaou, Michael E. Himmel, Yannick J. Bomble, Edward A. Bayer   +9 more
doaj   +1 more source

Clostridium butyricum and carbohydrate active enzymes contribute to the reduced fat deposition in pigs

iMeta, Volume 3, Issue 1, February 2024.
In the present study, we found significant differences in microbial composition and potential functional capacity among different gut locations in Jinhua pigs with distinct fatness phenotypes. Second, we identified that Jinhua pigs with lower fatness exhibited higher levels of short‐chain fatty acids in the colon, highlighting their enhanced ...
Lingyan Ma, Shiyu Tao, Tongxing Song, Wentao Lyu, Ying Li, Wen Wang, Qicheng Shen, Yan Ni, Jiang Zhu, Jiangchao Zhao, Hua Yang, Yingping Xiao   +11 more
wiley   +1 more source