Results 51 to 60 of about 139 (126)

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, Volume 16, Issue 4, Page 653-669, April 2026.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Unraveling essential cellulosomal components of the (Pseudo)Bacteroides cellulosolvens reveals an extensive reservoir of novel catalytic enzymes

Biotechnology for Biofuels, 2019
Background (Pseudo)Bacteroides cellulosolvens is a cellulolytic bacterium that produces the most extensive and intricate cellulosomal system known in nature. Recently, the elaborate architecture of the B.
Olga Zhivin-Nissan, Bareket Dassa, Ely Morag, Meital Kupervaser, Yishai Levin, Edward A. Bayer   +5 more
doaj   +1 more source

Bacterial Extracellular Vesicles in Biomedical Research and Clinical Translation

Microbial Biotechnology, Volume 19, Issue 4, April 2026.
Bacterial membrane vesicle biomedical applications. ABSTRACT Bacterial Extracellular Vesicles (bEVs) are lipid (single‐ or double‐bilayer) nanostructures secreted by virtually all bacteria that play fundamental roles in intercellular communication and have emerged as powerful, multifunctional tools in biomedicine. Their intrinsic ability to encapsulate
Alejandro Arce‐Rodríguez, Javier De la Peña Noya, José Manuel Borrero‐de Acuña   +2 more
wiley   +1 more source

Resolving dual binding conformations of cellulosome cohesin-dockerin complexes using single-molecule force spectroscopy

eLife, 2015
Receptor-ligand pairs are ordinarily thought to interact through a lock and key mechanism, where a unique molecular conformation is formed upon binding.
Markus A Jobst, Lukas F Milles, Constantin Schoeler, Wolfgang Ott, Daniel B Fried, Edward A Bayer, Hermann E Gaub, Michael A Nash   +7 more
doaj   +1 more source

A Scaffoldomics Platform for Modular In Vivo Enzyme Colocalisation and Its Application to Naringenin Biosynthesis

Microbial Biotechnology, Volume 19, Issue 3, March 2026.
A hierarchical assembly system was established in which the coding sequences for four docking enzymes and a scaffold are co‐assembled onto a single plasmid, thereby establishing a ‘scaffoldomics’ platform for the optimisation of multi‐enzyme biosynthetic pathways.
Marte Elias, Brecht De Paepe, Julie Vanderstraeten, Babette Lamote, Marjan De Mey, Yves Briers   +5 more
wiley   +1 more source

Transcytosis in the blood–cerebrospinal fluid barrier of the mouse brain with an engineered receptor/ligand system

Molecular Therapy: Methods & Clinical Development, 2015
Crossing the blood–brain and the blood–cerebrospinal fluid barriers (BCSFB) is one of the fundamental challenges in the development of new therapeutic molecules for brain disorders because these barriers prevent entry of most drugs from the blood ...
Héctor R Méndez-Gómez, Albert Galera-Prat, Craig Meyers, Weijun Chen, Jasbir Singh, Mariano Carrión-Vázquez, Nicholas Muzyczka   +6 more
doaj   +1 more source

Environmental and Ecological Monitoring with Biodegradable Technologies

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This review examines the development and application of wireless biodegradable sensors for environmental monitoring. It explores (bio)degradable materials, their degradation mechanisms in various environments, and non‐toxic fabrication techniques. Additionally, it addresses scalable production and sustainable powering solutions, emphasizing the high ...
Mohammad Javad Bathaei, Yaren Bathaei, Zhengwei Liao, Maryam Yazdanmehr, Sarab S. Sethi, Denys Nikolayev, Filipe Arroyo Cardoso, Clementine M. Boutry   +7 more
wiley   +1 more source

Engineering the cell surface display of cohesins for assembly of cellulosome-inspired enzyme complexes on Lactococcus lactis

Microbial Cell Factories, 2010
Background The assembly and spatial organization of enzymes in naturally occurring multi-protein complexes is of paramount importance for the efficient degradation of complex polymers and biosynthesis of valuable products.
Wieczorek Andrew S, Martin Vincent JJ
doaj   +1 more source

Artificial Enzymatic Electrochemistry

ChemElectroChem, Volume 12, Issue 21, November 3, 2025.
Artificial enzymatic electrochemistry has emerged as an effective method to extend the catalytic abilities of enzymes. This review explores the bioelectrochemical methods used to understand and optimize the structure and function of artificial enzymes.
Nya E. Black, Dara Cheng, Brandon P. Grasty, Dylan G. Boucher   +3 more
wiley   +1 more source

Bioactive polysaccharides and their potential health benefits in reducing the risks of metabolic syndrome: A review

Food Biomacromolecules, Volume 2, Issue 3, Page 288-314, September 2025.
Abstract Metabolic syndrome (MetS) is a complex noncommunicable condition characterized by central obesity, insulin resistance, hyperlipidemia, hypertension, and hyperglycemia. Epidemiological evidence shows that MetS affects a third of the global population; however, due to its complex pathogenesis and limited drug therapy options, the increasing ...
Josiah Owuor Oyalo, Evelyne Nkirote Gikundi, Mercy Adhiambo Ndiege, Kevin Omondi Aduol   +3 more
wiley   +1 more source