Results 141 to 150 of about 48,919 (268)

Changes in Blood Coagulation, Platelet Aggregation, and Lipid Metabolism in Rats Given Lipids Containing Docosahexaenoic Acid [PDF]

open access: bronze, 1997
Norihito Yamada   +7 more
openalex   +1 more source

Gut Microbiota Dysbiosis: Pathogenesis, Diseases, Prevention, and Therapy

open access: yesMedComm, Volume 6, Issue 5, May 2025.
ABSTRACT Dysbiosis refers to the disruption of the gut microbiota balance and is the pathological basis of various diseases. The main pathogenic mechanisms include impaired intestinal mucosal barrier function, inflammation activation, immune dysregulation, and metabolic abnormalities.
Yao Shen   +5 more
wiley   +1 more source

Cytoprotective effects of α-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, oleic acid and α-tocopherol on 7-ketocholesterol – Induced oxiapoptophagy: Major roles of PI3-K / PDK-1 / Akt signaling pathway and glutathione peroxidase activity in cell rescue

open access: yesCurrent Research in Toxicology
On murine N2a cells, 7-ketocholesterol induced an oxiapotophagic mode of cell death characterized by oxidative stress (reactive oxygen species overproduction on whole cells and at the mitochondrial level; lipid peroxidation), apoptosis induction (caspase-
Aline Yammine   +8 more
doaj  

Physiological effects of docosahexaenoic acid.

open access: bronze, 1993
Norio Nakamura   +2 more
openalex   +2 more sources

Stability of Plasma and Erythrocyte Membrane Phospholipids Fatty Acid Patterns in Preterm Babies Fed with or without Arachidonic (AA) and Docosahexaenoic (DHA) Acids [PDF]

open access: bronze, 1999
Manuel Moya Benavent   +4 more
openalex   +1 more source

Role of Inflammatory and Proresolving Mediators in Endothelial Dysfunction

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 136, Issue 5, May 2025.
ABSTRACT Excessive local inflammation is a common mechanism in many cardiovascular diseases (CVDs) such as hypertension, atherosclerosis and aortic aneurysms. In endothelial cells, inflammatory cytokines such as interferons, tumour necrosis factor alpha or interleukins increase oxidative stress and contractile prostanoids and the expression of adhesion
Ana M. Briones   +7 more
wiley   +1 more source

Reversible alterations in fatty acid composition of heart muscle membrane phospholipids induced by epinephrine in rats fed different fats

open access: yesJournal of Lipid Research, 1988
The effect of epinephrine on the fatty acid composition of heart muscle phospholipids was examined in rats fed diets containing 10% by weight of butter, corn oil, or cod liver oil.
V E Benediktsdottir, S Gudbjarnason
doaj  

Long‐term fasting induces a remodelling of fatty acid composition in erythrocyte membranes

open access: yesEuropean Journal of Clinical Investigation, Volume 55, Issue 5, May 2025.
Abstract Introduction Long‐term fasting (LF) activates an adaptative response to switch metabolic fuels from food glucose to lipids stored in adipose tissues. The increase in free fatty acid (FFA) oxidation during fasting triggers health benefits. We questioned if the changes in lipid metabolism during LF could affect lipids in cell membranes in humans.
Katharina Gewecke   +5 more
wiley   +1 more source

GPR37 Activation Alleviates Bone Cancer Pain via the Inhibition of Osteoclastogenesis and Neuronal Hyperexcitability

open access: yesAdvanced Science, Volume 12, Issue 14, April 10, 2025.
GPR37 activation alleviates bone cancer pain via peripheral and neuronal mechanisms. NPD1 or ARU targeting GPR37 in macrophages promotes IL‐10 release through β‐arrestin 2 recruitment, thereby inhibiting cancer‐induced osteoclastogenesis. Additionally, GPR37 activation in the DRG and SDH reduces the No. of action potentials and the frequency of sEPSCs,
Kaiyuan Wang   +10 more
wiley   +1 more source

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