Results 51 to 60 of about 2,732,817 (216)

Selenomethionine Regulates the Arachidonic Acid Metabolism‐Ferroptosis‐Inflammation Axis to Ameliorate Colitis

Animal Research and One Health, EarlyView.
Selenomethionine can ameliorate arachidonic acid‐induced colonic injury through synergistic mechanisms, including alleviating inflammatory responses, improving barrier integrity, enhancing antioxidant capacity by upregulating selenoprotein expression, selectively regulating AA metabolism to reduce pro‐inflammatory oxylipins and promote the production ...
Huihui Tian, Longzhu Zhou, Xiaohui Feng, Jialu Shen, Xiaoping Du, Qingyu Zhao, Yuchang Qin, Junmin Zhang, Chaohua Tang   +8 more
wiley   +1 more source

Whole‐Cell Production of Resolvin E2 and 17R‐Resolvin D5 by a Double‐Oxygenating 15S‐Lipoxygenase With 5S‐Lipoxygenase Activity From Pseudobdellovibrionaceae bacterium

Biotechnology and Bioengineering, EarlyView.
A recombinant whole‐cell platform expressing a bacterial 15S‐LOX exhibiting 5S‐LOX activity enabled the stereoselective production of RvE2 and 17R‐RvD5 from 18R‐HEPE and 17R‐HDHA, achieving final concentrations of 0.57 mM and 1.48 mM from 4.0 mM substrates, respectively, under optimized conditions.
Hee‐Gyeong Lee, Kyung‐Chul Shin, Deok‐Kun Oh   +2 more
wiley   +1 more source

Breastfeeding, infant formula supplementation, and Autistic Disorder: the results of a parent survey

International Breastfeeding Journal, 2006
Background Although Autistic Disorder is associated with several congenital conditions, the cause for most cases is unknown. The present study was undertaken to determine whether breastfeeding or the use of infant formula supplemented with ...
Schultz Stephen T, Klonoff-Cohen Hillary S, Wingard Deborah L, Akshoomoff Natacha A, Macera Caroline A, Ji Ming, Bacher Christopher   +6 more
doaj   +1 more source

Docosahexaenoic fatty acid reduces the pro‐inflammatory response induced by IL-1β in astrocytes through inhibition of NF-κB and AP-1 transcription factor activation

BMC Neuroscience, 2021
Background Astrocytes are responsible for a broad range of functions that maintain homeostasis in the brain. However, their response to the pro-inflammatory cytokines released by activated microglia in various neurological pathologies may exacerbate ...
Emilia Zgórzyńska, Dawid Stulczewski, Barbara Dziedzic, Kuan-Pin Su, Anna Walczewska   +4 more
doaj   +1 more source

Docosahexaenoic Acid as Master Regulator of Cellular Antioxidant Defenses: A Systematic Review

Antioxidants, 2023
Docosahexaenoic acid (DHA) is a polyunsaturated fatty acid that benefits the prevention of chronic diseases. Due to its high unsaturation, DHA is vulnerable to free radical oxidation, resulting in several unfavorable effects, including producing ...
Sara Margherita Borgonovi, Stefania Iametti, Mattia Di Nunzio   +2 more
doaj   +1 more source

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini, Mallorie P. Jenne, Michael L. Piacentino   +2 more
wiley   +1 more source

Docosahexaenoic Acid Regulates Serum Amyloid a Protein to Promote Lipolysis through down Regulation of Perilipin

, 2011
Docosahexaenoic acid (DHA) increases lipolysis and decreases lipogenesis through several pathways. DHA also enhances the expression of serum amyloid A protein (SAA), a possible lipid metabolism related gene.
WANG, YA-CHIN;KUO, WEN-HONG;CHEN, CHING-YI;LIN, HSIN-YU;WU, HSIN-TING;LIU, BING-HSIEN;CHEN, CHIA-HUNG;CHANG, KING-JEN;DING, SHIH-TORNG, 王雅青;郭文宏;陳靜宜;林欣瑜;吳欣庭;劉秉勳;陳佳宏;張金堅;丁詩同   +1 more
core   +1 more source

Precision Fermentation for Next Generation Food Ingredients: Technological Foundations, Food Applications, Sustainability, and Regulatory Challenges

Food Bioengineering, EarlyView.
Precision fermentation uses engineered microorganisms to produce targeted food ingredients, including proteins, enzymes, lipids, flavors, vitamins, and bioactives. This review examines its technological foundations, food applications, safety, sustainability, economics, regulation, and consumer acceptance, emphasizing that performance depends on host ...
Nora Ali Hassan, Rawaa H. Tlay, Tarek Gamal Abedelmaksoud   +2 more
wiley   +1 more source

Evaluation of Plasma AA/DHA+EPA Ratio in Obese Romanian Children

Romanian Journal of Laboratory Medicine, 2021
The aim of the study was to evaluate the plasma profile of arachidonic acid (AA), docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA), as well to analyze the relationship of Omega 6/Omega 3 ratio with anthropo-metric parameters and insulin ...
Huțanu Adina, Zaharia Mihaela, Farczadi Lenard, Pașcanu Ionela Maria, Pop Raluca Monica, Dobreanu Minodora   +5 more
doaj   +1 more source

Docosahexaenoic acid normalizes QT interval in long QT type 2 transgenic rabbit models in a genotype-specific fashion [PDF]

, 2021
AIM: Long QT syndrome (LQTS) is a cardiac channelopathy predisposing to ventricular arrhythmias and sudden cardiac death. Since current therapies often fail to prevent arrhythmic events in certain LQTS subtypes, new therapeutic strategies are needed ...
Hornyik, Tibor,, Perez Feliz, Stefanie, Liin, Sara I, Larsson, Hans Peter,, Odening, Katja E, Odening, Katja E.,, Castiglione, Alessandro, Jowais, Jessica J, Perez-Feliz, Stefanie, Koren, Gideon,, Brunner, Michael,, Koren, Gideon, Zehender, Manfred, Wülfers, Eike M, Brunner, Michael, Bode, Christoph, Perez-Feliz, Stefanie,, Bode, Christoph,, Wuelfers, Eike M.,, Giammarino, Lucilla, Baczko, Istvan,, Rieder, Marina, Wülfers, Eike Moritz, Baczkó, István, Bősze, Zsuzsanna, Edler, Isak,, Bosze, Zsuzsanna,, Odening, Katja, Giammarino, Lucilla,, Hornyik, Tibor, Zehender, Manfred,, Varró, András, Castiglione, Alessandro,, Jowais, Jessica J.,, Edler, Iask, Larsson, Hans Peter, Liin, Sara,, Rieder, Marina,, Varro, Andras,, Rieder Marina, Varró András, Zehender Manfred, Baczkó István, Jowais Jessica J., Brunner Michael, Edler Iask, Perez-Feliz Stefanie, Bode Christoph, Giammarino Lucilla, Koren Gideon, Castiglione Alessandro, Hornyik Tibor, Bősze Zsuzsanna, Wülfers Eike M., Christoph Bode, Jessica J Jowais, Michael Brunner, Stefanie Perez-Feliz, Iask Edler, Eike M Wülfers, Lucilla Giammarino, Tibor Hornyik, Manfred Zehender, András Varró, Sara I Liin, Gideon Koren, Katja E Odening, Marina Rieder, Zsuzsanna Bősze, Hans Peter Larsson, István Baczkó, Alessandro Castiglione   +71 more
core   +2 more sources