Results 101 to 110 of about 2,701,337 (214)

LGR6 couples maresin 1 signaling to glycolytic flux and protein lactylation for the rescue of diabetic cardiomyopathy

Journal of Diabetes Investigation, EarlyView.
MaR1 activates LGR6‐AMPK signaling to restore metabolic flexibility in diabetic hearts. Glycolytic recovery replenishes intracellular lactate to rescue protective protein lysine lactylation, which reactivates PINK1/Parkin‐mediated mitophagy to eliminate damaged mitochondria.
Bin Feng, Chao Chen, Lin Chen, Yuqiong Chen, Wenjun Mao, Peiran Yu, Hao Yu, Bimin Shi, Nannan Zhang   +8 more
wiley   +1 more source

Acceptance and Preference of a Commercial Dry Renal Diet in Healthy Cats: An In‐Home Proof‐of‐Concept Trial

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Cats diagnosed with chronic kidney disease (CKD) have shown a better prognosis when consuming an appropriate renal diet, which makes its palatability a key factor in ensuring proper compliance. A proof‐of‐concept trial with a commercial dry renal diet was conducted in 33 healthy cats to assess its palatability over three consecutive 6‐day ...
Tomás Rodrigues Magalhães, Ronald Jan Corbee, Felisbina Luísa Queiroga, Ana Luísa Lourenço   +3 more
wiley   +1 more source

Docosahexaenoic acid and arachidonic acid are fundamental supplements for the induction of neuronal differentiation

Journal of Lipid Research, 2007
Cell replacement therapy is being investigated for the treatment of neurodegenerative disorders. Adult autologous bone marrow-derived mesenchymal stem cells (MSCs) have been induced to differentiate into neuron-like cells harboring a variety of neuronal ...
Inna Kan, Eldad Melamed, Daniel Offen, Pnina Green   +3 more
doaj   +1 more source

Driving into the Factory of Docosahexaenoic Acid (DHA), Microalgae

Microalgae, with their rapid growth and cost-effective cultivation, have emerged as a potent source of bioactive compounds, including lipids. Docosahexaenoic acid (DHA), an omega-3 polyunsaturated fatty acid, is an important fraction of microalgal lipids, which holds a crucial place in human nutrition and health.
Nahid Hosseinzadeh Gharajeh, Mohammad Amin Hejazi   +1 more
openaire   +1 more source

Similarities Between the Lipid Profiles of Skin and Liver of European Sea Bass (Dicentrarchus labrax) Fed Diets With Different Lipid Content

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT The fatty acid composition of fish is influenced by species, age, diet, and tissues, which respond differently to dietary lipids. This study examined how two commercial diets with contrasting polyunsaturated fatty acid (PUFA) profiles, affecting eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), alter the fatty acid composition in ...
Daniel González‐Silvera, Cristóbal Espinosa‐Ruiz, M. Ángeles Esteban   +2 more
wiley   +1 more source

Effects of arachidonic and docosahexaenoic acids on secretion and degradation of bile salt-dependent lipase in AR4-2J cells

Journal of Lipid Research, 2001
In this study we demonstrated that two polyunsaturated fatty acids, arachidonic acid (AA, n–6) and docosahexaenoic acid (DHA, n–3), modulate the secretion of bile salt-dependent lipase (BSDL) by pancreatic AR4-2J cells.
Josette Le Petit-Thévenin, Nadine Bruneau, Alain Nganga, Dominique Lombardo, Alain Vérine   +4 more
doaj   +1 more source

Diet‐Related Differences Predominate Over Breed‐Associated Differences in Hepatic Lipid Metabolism, Antioxidant Vitamins and Lipid Quality Indices Among Beef Cattle

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Understanding how nutritional management and genetic background influence hepatic metabolism is important for improving the nutritional quality of bovine products in tropical production systems. This study evaluated breed‐associated differences under a common dietary regimen and diet‐related differences within the Nelore breed with respect to ...
Laíza de Kássia Mendes da Conceição, José de Brito Lourenço‐Júnior, Jamile Andréa Rodrigues da Silva, Leonel António Joaquim, Mariana Jucá Moraes, Thomaz Cyro Guimarães de Carvalho Rodrigues, Joana Inês Ferreira, Ana Maria Ramos Fontes, Maria Pinheiro Spínola, Érica Coutinho David, Antônio Vinicius Correa Barbosa, Bruno Cabral Soares, José António Mestre Prates   +12 more
wiley   +1 more source

Function of DHA Algal Oil and Its Application in Health Food

Shipin gongye ke-ji
Docosahexaenoic acid (DHA), an ω-3 polyunsaturated fatty acid, is mainly derived from fish oil and algal oil. Algal oil has a high DHA content and good safety, and is widely used in the food industry.
Jinhong GUO, Wei SONG, Hao DUAN, Duo FENG, Wenjie YAN   +4 more
doaj   +1 more source

The Effects of Docosahexaenoic Acid (DHA) Dietary Supplementation in a Mouse Model of Stargardt-like Macular Dystrophy (STGD3) [PDF]

, 2013
Underlying mechanisms of how docosahexaenoic acid (DHA) might impact the progression of macular degeneration are unknown. We relied on the ELOVL4 mouse model of juvenile macular degeneration, STGD3, to test the hypothesis that antenatal DHA dietary ...
Hong, Mandy
core   +1 more source

Periodontal Salutogenesis: Why Are Some People Resistant to Oral Microbial Dysbiosis and Destructive Inflammation?

Journal of Periodontal Research, EarlyView.
Emerging evidence suggests that periodontal health is not simply the absence of disease, but the result of a dynamic interaction between biological resilience, healthy lifestyles, adaptive coping mechanisms, and supportive environments. This results in a strong sense of coherence, which is not only a psychological state but also a biological state ...
Bruno G. Loos, Magda Feres, William V. Giannobile, Hatice Hasturk, Egija Zaura   +4 more
wiley   +1 more source