Results 231 to 240 of about 5,021,709 (330)

Chemo‐Enzymatic Synthesis of Mixed Docosahexaenoic Acid Phosphatidylcholine Conjugates

open access: yesEuropean Journal of Organic Chemistry, Volume 28, Issue 17, May 21, 2025.
An efficient chemo‐enzymatic synthesis method is proposed for the production of mixed DHA (Docosahexaenoic acid) phosphatidylcholines, allowing access to both regioisomers with DHA positioned at either the sn1 or sn2 site. Regioisomers of acetate derivatives (AceDoPC®, DoAcePC, stabilized forms of LPC‐DHA) and phenolic‐DHA‐PCs (antioxidant drugs) were ...
Jordan Lehoux   +6 more
wiley   +1 more source

Inhibition of Aberrant Activated Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis by Leishmania Peptide via the Regulation of Fatty Acid Synthesis Metabolism

open access: yesAdvanced Science, Volume 12, Issue 19, May 22, 2025.
LACK156‐173 is internalized into RA‐FLSs via CAPN2‐mediated endocytosis and inhibits the aggressive phenotype of RA‐FLSs by restoring dysregulated fatty acid synthesis metabolism mediated by overexpressed FASN. The findings suggest that targeting the restoration of fatty acid metabolism could potentially alleviate synovial invasion and joint damage in ...
Jianling Su   +17 more
wiley   +1 more source

Assessing the efficiency of ethyl acetate for lipid extraction as an alternative to the Folch method in selected marine low‐trophic species

open access: yesJournal of the American Oil Chemists' Society, Volume 102, Issue 5, Page 871-883, May 2025.
The EtOAc method offers a straightforward and environmentally friendly protocol for lipid extraction, showing efficiency comparable to the Folch method, particularly in extracting lipids with high proportions of neutral lipids and free fatty acids. Abstract The recognized health benefits associated with marine omega‐3 polyunsaturated fatty acids (PUFAs)
Ying Wang   +3 more
wiley   +1 more source

Amaranthus spinosus Linn. Extract as an Innovative Strategy to Regulate Biomarkers for Ovarian Hyperthecosis via Circular RNA (hsa‐circ‐0001577): Evidence From Biochemical, Metabolomics, Histological, and Phytochemical Profiling

open access: yesFood Science &Nutrition, Volume 13, Issue 5, May 2025.
A significant improvement in hormonal and oxidative stress biomarkers was observed in rats treated with Amaranthus spinosus, especially at high doses, after induction of ovarian hyperthecosis. Amaranthus spinosus could be a management approach for ovarian hyperthecosis via regulating circRNA (hsa‐circ‐0001577), disturbed hormonal balance, and ...
Naglaa M. Ammar   +9 more
wiley   +1 more source

The Interplay of Food Insecurity, Resilience, Stress Mindset, and Mental Distress: Insights From a Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background and Aims In the United States, food insecurity (FI) is a serious health issue potentially affecting brain function. While neuroimaging suggests that diet quality influences brain functions, gaps remain regarding its impact on resilience, stress mindset, and mental distress, particularly across age and gender.
Lina Begdache   +5 more
wiley   +1 more source

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