Results 1 to 10 of about 1,794 (108)

Docosatrienoic Acid Inhibits Melanogenesis Partly through Suppressing the Intracellular MITF/Tyrosinase Axis [PDF]

Pharmaceuticals
Melanogenesis, essential for skin photoprotection and pigmentation, can lead to disorders like melasma and hyperpigmentation, which are challenging to treat and affect quality of life.
Kyoung Mi Moon, Min-Kyeoun Lee, Su-Yeon Park, Jaeseong Seo, Ah-reum Kim, Bonggi Lee   +5 more
doaj   +7 more sources

Stepwise metabolic engineering of docosatrienoic acid - an ω3 very long-chain polyunsaturated fatty acid with potential health benefits in Brassica carinata. [PDF]

Plant Biotechnol J, 2023
Very long-chain polyunsaturated fatty acids (VLCPUFAs) areessential components of cell membranes and precursors forbioactive compounds regulating important physiological pro-cesses in humans and animals. Lack or imbalance of these fattyacids can lead to various physiological problems in humans suchas immunological disorders, neurological conditions and
Meesapyodsuk D, Sun K, Zhou R, Thoms K, Qiu X.   +4 more
europepmc   +7 more sources

Unveiling Pharmacological Promise of Mangifera indica (Haribhanga) Peel Extract: Exploring an Untapped Cultivar Through Biochemical and Computational Approaches [PDF]

Scientifica
The Haribhanga is one of the most renowned varieties of mango native to the Rangpur region of Bangladesh. The study aimed to explore the in vitro and in vivo pharmacological potentialities of the methanolic extract of Mangifera indica (Haribhanga) (MEMI)
Mst. Hajera Khatun, Saad Ahmed Sami, Farhana Sultana Mim, Pappu Kumar, Ariful Islam, Injamam Al Mahamud Rian, Md. Ashikur Rahman, Sharmin Islam Riya, Md. Lokman, Al Mamun, Md. Anwarul Haque, Mst. Sarmina Yeasmin, G. M. Masud Rana, Jaytirmoy Barmon   +13 more
doaj   +4 more sources

Short Communication: Eicosatrienoic Acid and Docosatrienoic Acid Do Not Promote Vaccenic Acid Accumulation in Mixed Ruminal Cultures [PDF]

Journal of Dairy Science, 2006
Previous research found that docosahexaenoic acid (C22:6n-3) was a component of fish oil that promotes trans-C18:1 accumulation in ruminal cultures when incubated with linoleic acid. The objective of this study was to determine if eicosatrienoic acid (C20:3n-3) and docosatrienoic acid (C22:3n-3), n-3 fatty acids in fish oil, promote accumulation of ...
A A, AbuGhazaleh, L D, Holmes, B N, Jacobson, K F, Kalscheur   +3 more
exaly   +5 more sources

Comprehensive molecular characteristics of hepatocellular carcinoma based on multi-omics analysis [PDF]

BMC Cancer
Background The high heterogeneity of hepatocellular carcinoma (HCC) poses challenges for precision treatment strategies. This study aims to use multi-omics methodologies to better understand its pathogenesis and discover biomarkers.
Ying-Ying Wang, Wan-Xia Yang, Jiang-Ying Cai, Fang-Fang Wang, Chong-Ge You   +4 more
doaj   +3 more sources

Effect of Sex on Intestinal Microbial Metabolites of Hainan Special Wild Boars [PDF]

Animals
The intestinal microbiota and its metabolites are essential for the health and growth development of animals. Current research indicates that sex has a certain impact on the structure and function of the intestinal microbiota, but there are few reports ...
Xiaozhe Wang, Qiong Wen, Hongfen Wu, Wenchuan Peng, Keqi Cai, Zhen Tan, Wei Na, Kebang Wu   +7 more
doaj   +3 more sources

Identifying biomarkers distinguishing sepsis after trauma from trauma-induced SIRS based on metabolomics data: a retrospective study [PDF]

Scientific Reports
Sepsis after trauma and trauma-induced SIRS have similar symptoms, making their differentiation challenging. Therefore, biomarkers are needed to differentiate between sepsis after trauma and trauma-induced SIRS.
Yi Gou, Jing-jing Liu, Jun-fei Zhang, Wan-peng Yang, Jian-Zhong Yang, Ke Feng   +5 more
doaj   +3 more sources

Identifying early predictive and diagnostic biomarkers and exploring metabolic pathways for sepsis after trauma based on an untargeted metabolomics approach [PDF]

Scientific Reports
Systemic inflammatory response syndrome (SIRS) and organ dysfunction make it challenging to predict which major trauma patients are at risk of developing sepsis.
Yi Gou, Bo-Hui Lv, Jun-Fei Zhang, Sheng-Ming Li, Xiao-Ping Hei, Jing-Jing Liu, Lei Li, Jian-Zhong Yang, Ke Feng   +8 more
doaj   +3 more sources

Co-expressing Eranthis hyemalis lysophosphatidic acid acyltransferase 2 and elongase improves two very long chain polyunsaturated fatty acid production in Brassica carinata

Metabolic Engineering Communications, 2021
Docosadienoic acid (DDA, 22:2–13,16) and docosatrienoic acid (DTA, 22:3–13,16,19) are two very long chain polyunsaturated fatty acids (VLCPUFAs) that are recently shown to possess strong anti-inflammatory and antitumor properties.
Dauenpen Meesapyodsuk, Yi Chen, Shengjian Ye, Robert G. Chapman, Xiao Qiu   +4 more
doaj   +3 more sources

Exploring metabolite diversity in global rapeseed germplasm: insights into ecotypes, geographical influences, and correlations with diabetes [PDF]

BMC Plant Biology
Background Rapeseed oil is widely recognized for its health benefits; however, the relationships between its metabolites and factors such as ecotypes, geographical regions, plant traits, and diabetes risk remain poorly understood.
Pei Wang, Yungu Zhai, Yongfeng Wang, Bing Zhao, Xiao Wang, Fei Liu, Cuiling Yang, Shicheng Zhang, Haojie Liu, Xuebin Zhang, Daojie Wang   +10 more
doaj   +2 more sources