Results 51 to 60 of about 16,883 (239)

Incidence and impact of low-level viremia among people living with HIV who received protease inhibitor- or dolutegravir-based antiretroviral therapy

International Journal of Infectious Diseases, 2021
Objectives: The impact of very low-level viremia (VLLV) and low-level viremia (LLV) are rarely investigated among people living with HIV (PLWH) receiving dolutegravir- vs protease inhibitor (PI)-based antiretroviral therapy (ART).
Guan-Jhou Chen, Hsin-Yun Sun, Sui-Yuan Chang, Aristine Cheng, Yu-Shan Huang, Sung-Hsi Huang, Yi-Chia Huang, Yi-Ching Su, Wen-Chun Liu, Chien-Ching Hung   +9 more
doaj   +1 more source

Immuno-hematological parameters among adult HIV patients before and after initiation of Dolutegravir based antiretroviral therapy, Addis Ababa, Ethiopia

PLoS ONE
Background Immuno-hematological abnormalities are common among HIV infected individuals as well as patients with highly active antiretroviral therapy (HAART).
Ayantu Gudina, Moges Wordofa, Fekadu Urgessa   +2 more
semanticscholar   +1 more source

Viral suppression in the era of transition to dolutegravir-based therapy in Cameroon: Children at high risk of virological failure due to the lowly transition in pediatrics

Medicine, 2023
This study aimed to compare viral suppression (VS) between children, adolescents, and adults in the frame of transition to dolutegravir (DTG)-based antiretroviral therapy (ART) in the Cameroonian context. A comparative cross-sectional study was conducted
J. Fokam, Alex Durand Nka, Flore Yollande Mamgue Dzukam, Jeremiah Efakika Gabisa, Yagai Bouba, Michel Carlos Tommo Tchouaket, A. Ka’e, Ezechiel Ngoufack Jagni Semengue, D. Takou, S. Moudourou, N. Fainguem, W. Pabo, Rachel Audrey Nayang Mundo, Aurelie Minelle Kengni Ngueko, Collins Ambe Chenwi, Junie Flore Yimga, Marie Krystel Nnomo Zam, Rachel Simo Kamgaing, Charlotte Tangimpundu, N. Kamgaing, Anne-Esther Njom-Nlend, Paul Ndombo Koki, Daniel Kesseng, Suzie Ndiang Tetang, E. Kembou, Lifanda Ebiama Lifanda, B. Pamen, Alice Ketchaji, Edith Michele Saounde Temgoua, S. Billong, Anne-Cécile Zoung-Kanyi Bissek, Hamsatou Hadja, E. G. Halle, V. Colizzi, C. Perno, S. Sosso, A. Ndjolo   +36 more
semanticscholar   +1 more source

Role of Dolutegravir-based antiretroviral treatment in achieving an undetectable HIV-1 viral load among women attending prevention of mother-to-child transmission clinics in Addis Ababa, Ethiopia

SAGE Open Medicine
Objectives: This study aimed to determine the prevalence of detectable HIV-1 viral load and associated factors among pregnant and lactating women on Dolutegravir-based and non-Dolutegravir-based regimens.
Belete Woldesemayat, Yimam Getaneh, Sisay Adane, Ajanaw Yizengaw, Amelework Yilma, Shambel Araya Haile, Kidist Zealiyas   +6 more
doaj   +1 more source

Dolutegravir based antiretroviral therapy compared to other combined antiretroviral regimens for the treatment of HIV-infected naive patients: A systematic review and meta-analysis.

PLoS ONE, 2019
BackgroundNumerous randomized clinical trials (RCTs) were conducted to evaluate dolutegravir based triple antiretroviral therapy (ART) compared to other triple antiretroviral regimens in naïve patients, and a summary of the available evidence is required
Mario Cruciani, Saverio G Parisi
doaj   +1 more source

Long‐Term Control of Human Papillomavirus‐Related Focal Epithelial Hyperplasia in an Human Immunodeficiency Virus‐Positive Patient Using Methylene Blue‐Mediated Photodynamic Therapy. A Case Report

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Background Human papillomavirus (HPV) infections are a major cause of oral lesions, and in individuals living with HIV, lesions such as focal epithelial hyperplasia (FEH) may persist or exhibit atypical features, potentially progressing to more severe conditions if untreated.
Juliana Cristina Oliverio de Araújo, Hermano Camelo Paiva, Paula Margarida Meyer Faara, Og Fray Junior, Martha Simões Ribeiro   +4 more
wiley   +1 more source

Comparative safety of dolutegravir-based or efavirenz-based antiretroviral treatment started during pregnancy in Botswana: an observational study

The Lancet Global Health, 2018
Summary: Background: Global rollout of dolutegravir-based antiretroviral therapy (ART) has been hampered in part by insufficient safety data in pregnancy.
Rebecca Zash, MD, Denise L Jacobson, PhD, Modiegi Diseko, BA, Gloria Mayondi, BSc, Mompati Mmalane, MD, Max Essex, ProfPhD, Tendani Gaolethe, MD, Chipo Petlo, BA, Shahin Lockman, MD, Lewis B Holmes, MD, Joseph Makhema, MBBS, Roger L Shapiro, MD   +11 more
doaj   +1 more source

Effect of Dolutegravir regimen against other regimens on some hematological parameters, CD4 count and viral load of people living with HIV infection in South Eastern Nigeria

Medicine, 2023
Background: Appropriate usage of highly active antiretroviral therapy (HAART) suppresses human immunodeficiency virus (HIV) replication. One of such HAART is dolutegravir (DTG) containing regimen which Nigeria included in her national protocol, as the ...
Stella N Echefu, J. Udosen, E. Akwiwu, J. Akpotuzor, E. Obeagu   +4 more
semanticscholar   +1 more source

Exploring the impact of baseline and on‐treatment variables on durability of responses to fostemsavir through weeks 96 and 192 in the phase 3 BRIGHTE study

HIV Medicine, EarlyView.
Abstract Objectives The gp120‐directed attachment inhibitor fostemsavir was effective in people with multidrug‐resistant (MDR) HIV‐1 in the BRIGHTE study. Understanding factors associated with virologic response can help clinicians optimize treatment and identify individuals for fostemsavir‐based regimens.
M. Gartland, X. Wang, Q. Liao, B. Li, F. Du, M. Krystal, A. R. Tenorio, A. Pierce, J. R. Castillo‐Mancilla   +8 more
wiley   +1 more source

Dolutegravir induces FOLR1 expression during brain organoid development

Frontiers in Molecular Neuroscience
During the first month of pregnancy, the brain and spinal cord are formed through a process called neurulation. However, this process can be altered by low serum levels of folic acid, environmental factors, or genetic predispositions.
Carlo Donato Caiaffa, Gabriel L Tukeman, Christian Z Delgado, Yogeshwari S. Ambekar, T. Mekonnen, Manmohan Singh, Victoria Rodriguez, Emily Ricco, Daniel C Kraushaar, S. Aglyamov, G. Scarcelli, K. Larin, Richard H. Finnell, Robert M. Cabrera   +13 more
semanticscholar   +1 more source