Results 101 to 110 of about 18,832,580 (328)
Crystal structure of streptokinase β‐domain [PDF]
Streptokinase, a 47 kDa secreted protein of hemolytic strains of streptococci, is a human plasminogen activator and contains three structural domains linked by flexible loops. We describe here the crystal structure of the isolated streptokinase middle (SKβ) domain determined at 2.4 Å resolution. Among the functionally important structural features is a
Wang, Xiaoqiang +3 more
openaire +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Sintered Pr-Nd-Fe-B-based permanent magnets with 10 and 13 wt. % of Pr were prepared by traditional technology and then subjected to various heat treatments.
K. Skotnicová +9 more
doaj
Features of the dynamic pyroelectric response and the local domain structure in PZN-PT crystals
In this work, the polarization distribution over the volume of (1-x)Pb(Zn1/3Nb2/3)O3-xPbTiO3 crystals of the directions [001] and [111] was studied by the method of dynamic pyroelectric response.
I.L. Kislova +5 more
doaj +1 more source
PP licensing in nominalizations [PDF]
In this paper we compare the distribution of PPs introducing external arguments in nominalizations with PPs introducing external arguments in the verbal domain.
Alexiadou, Artemis +2 more
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
CDD/SPARCLE: functional classification of proteins via subfamily domain architectures
NCBI's Conserved Domain Database (CDD) aims at annotating biomolecular sequences with the location of evolutionarily conserved protein domain footprints, and functional sites inferred from such footprints.
Aron Marchler-Bauer +21 more
semanticscholar +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Study of the domain structure of ferroelectric crystals TGS with a periodic distribution of the impurity [PDF]
A complex research of the features of the triglycine sulfate crystals domain structure with the periodic distribution of the chromium ions Cr+3impurity TGS-TGS+Cr on the optical (method NLC) and the micro level (the domain structure according to the ...
Victor Shut +5 more
doaj
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source

