Results 101 to 110 of about 18,832,580 (328)

Crystal structure of streptokinase β‐domain [PDF]

open access: yesFEBS Letters, 1999
Streptokinase, a 47 kDa secreted protein of hemolytic strains of streptococci, is a human plasminogen activator and contains three structural domains linked by flexible loops. We describe here the crystal structure of the isolated streptokinase middle (SKβ) domain determined at 2.4 Å resolution. Among the functionally important structural features is a
Wang, Xiaoqiang   +3 more
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Influence of heat treatment on the structural and magnetic characteristics of (NdxPr1-x)2Fe14B-based magnetic material for low-temperature application

open access: yesMetalurgija, 2016
Sintered Pr-Nd-Fe-B-based permanent magnets with 10 and 13 wt. % of Pr were prepared by traditional technology and then subjected to various heat treatments.
K. Skotnicová   +9 more
doaj  

Features of the dynamic pyroelectric response and the local domain structure in PZN-PT crystals

open access: yesФизико-химические аспекты изучения кластеров, наноструктур и наноматериалов
In this work, the polarization distribution over the volume of (1-x)Pb(Zn1/3Nb2/3)O3-xPbTiO3 crystals of the directions [001] and [111] was studied by the method of dynamic pyroelectric response.
I.L. Kislova   +5 more
doaj   +1 more source

PP licensing in nominalizations [PDF]

open access: yes, 2008
In this paper we compare the distribution of PPs introducing external arguments in nominalizations with PPs introducing external arguments in the verbal domain.
Alexiadou, Artemis   +2 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

CDD/SPARCLE: functional classification of proteins via subfamily domain architectures

open access: yesNucleic Acids Res., 2016
NCBI's Conserved Domain Database (CDD) aims at annotating biomolecular sequences with the location of evolutionarily conserved protein domain footprints, and functional sites inferred from such footprints.
Aron Marchler-Bauer   +21 more
semanticscholar   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Study of the domain structure of ferroelectric crystals TGS with a periodic distribution of the impurity [PDF]

open access: yesVestnik of Vitebsk State Technological University, 2015
A complex research of the features of the triglycine sulfate crystals domain structure with the periodic distribution of the chromium ions Cr+3impurity TGS-TGS+Cr on the optical (method NLC) and the micro level (the domain structure according to the ...
Victor Shut   +5 more
doaj  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

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