Results 281 to 290 of about 101,529 (354)
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Accurate assay of dopa decarboxylase by preventing nonenzymatic decarboxylation of dopa
Analytical Biochemistry, 1983The nonenzymatic decarboxylation of dopa was completely blocked by both 2-mercaptoethanol and EDTA together over the wide range of pH. This finding made it possible to measure the activity of dopa decarboxylase precisely even at an alkaline pH value. The pH optimum of dopa decarboxylase was found to be pH 7.0 and the Km value for dopa was determined to
Sachiko Okuno, Hitoshi Fujisawa
exaly +3 more sources
Zeitschrift f�r Neurologie, 1972
l-DOPA therapy of Parkinsonism by mouth, today universally accepted, may induce undesirable effects which can sometimes be of a certain severity.
C, Fazio +6 more
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l-DOPA therapy of Parkinsonism by mouth, today universally accepted, may induce undesirable effects which can sometimes be of a certain severity.
C, Fazio +6 more
openaire +2 more sources
L‐DOPA for Parkinson's disease—a bittersweet pill
European Journal of Neuroscience, 20183,4‐dihydroxy‐L‐phenylalanine (L‐DOPA) is the gold standard treatment for Parkinson's disease. It has earned that title through its highly effective treatment of some of the motor symptoms in the early stages of the disease but it is a far from perfect ...
E. Lane
semanticscholar +1 more source
Movement Disorders, 1999
"Punding" is a stereotypical motor behavior in which there is an intense fascination with repetitive handling and examining of mechanical objects, such as picking at oneself or taking apart watches and radios or sorting and arranging of common objects, such as lining up pebbles, rocks, or other small objects.
H H, Fernandez, J H, Friedman
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"Punding" is a stereotypical motor behavior in which there is an intense fascination with repetitive handling and examining of mechanical objects, such as picking at oneself or taking apart watches and radios or sorting and arranging of common objects, such as lining up pebbles, rocks, or other small objects.
H H, Fernandez, J H, Friedman
openaire +2 more sources
DOPA Metabolism in Neuroblastoma
Medical and Pediatric Oncology, 1980AbstractBlood plasma samples from 60 neuroblastoma patients prior to, during, and following treatment were studied for their content of circulating DOPA using a radioenzymatic assay. Normal values were established from children who were tumor‐free or had other nonneurogenic tumors. The highest plasma DOPA concentration in tumor‐free or nonneuroblastoma
L, Helson, G A, Johnson, R, Smith
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BMJ, 2010
Karen Low helps Teresa Harding tell the story of her life with dopa responsive dystonia, which was not diagnosed until she was in her mid ...
Karen, Low +2 more
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Karen Low helps Teresa Harding tell the story of her life with dopa responsive dystonia, which was not diagnosed until she was in her mid ...
Karen, Low +2 more
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Characterization of dopa decarboxylase
Life Sciences, 1973Publisher Summary This chapter discusses characteristics of DOPA decarboxylase. DOPA decarboxylase, which catalyses the conversion of L-dopa to dopamine, was the first of the catecholamine biosynthetic enzymes to be discovered. In a study, the dopa decarboxylase of hog kidney was purified to homogeneity.
WALLACE DAIRMAN +2 more
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Andrologia, 2009
A clinical investigation of L-Dopa on idiopathic oligozoospermia is carried out. Thirty nine male oligozoospermic patients with primary sterility were divided in two groups. The first group of 25 patients was treated with 500 mg a day during two months. The second group of 14 patients received 750 mg a day for the same time.
J C, Lavieri, A A, Pierini
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A clinical investigation of L-Dopa on idiopathic oligozoospermia is carried out. Thirty nine male oligozoospermic patients with primary sterility were divided in two groups. The first group of 25 patients was treated with 500 mg a day during two months. The second group of 14 patients received 750 mg a day for the same time.
J C, Lavieri, A A, Pierini
openaire +2 more sources
Current Opinion in Neurology, 1995
The past 18 months have seen significant advances in our understanding of dopa(dihydroxyphenylalanine)-responsive dystonia. Clinical investigations have broadened the spectrum of disease with particular attention manifestations in infancy. Pathophysiological investigations have revealed features that distinguish dopa-responsive dystonia from childhood ...
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The past 18 months have seen significant advances in our understanding of dopa(dihydroxyphenylalanine)-responsive dystonia. Clinical investigations have broadened the spectrum of disease with particular attention manifestations in infancy. Pathophysiological investigations have revealed features that distinguish dopa-responsive dystonia from childhood ...
openaire +2 more sources
Nature, 1970
This new treatment for an old disease has its origins in pharmacological research of the late 1950s. There is still not full agreement about how L-dopa functions in the nervous system, but, as this review shows, there is ample evidence to support the clinical work in progress since 1961.
D B, Calne, M, Sandler
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This new treatment for an old disease has its origins in pharmacological research of the late 1950s. There is still not full agreement about how L-dopa functions in the nervous system, but, as this review shows, there is ample evidence to support the clinical work in progress since 1961.
D B, Calne, M, Sandler
openaire +2 more sources