Results 61 to 70 of about 101,529 (354)
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Neurobiology of Disease, 2010 Benefit and motor side effects of l-DOPA in Parkinson's disease have been related to dopamine transmission in the striatum. However, the putative involvement of serotonergic neurons in the dopaminergic effects of l-DOPA suggests that the striatum is not ...
Sylvia Navailles +3 more
doaj +1 more source
Combination Treatment of Icariin and L-DOPA Against 6-OHDA-Lesioned Dopamine Neurotoxicity
Frontiers in Molecular Neuroscience, 2018 Until now, the dopamine (DA) precursor, L-3,4-dihydroxyphenylalanine (L-DOPA), remains the gold standard effective drug therapy for Parkinson’s disease (PD) patients.
Di-Sheng Lu +7 more
doaj +1 more source
, 2017 Purpose: To develop elite genotypes in Mucuna pruriens (L.) DC with high L-DOPA (L-3, 4 dihydroxyphenylalanine) yields, with non-itching characteristics and better adaptability by applying γ-irradiation.
Deepti Yadav (3365363) +4 more
core +1 more source
Synthesis of L-DOPA based pigments with different physic-chemical properties [PDF]
, 2018 Using air- or Fe2+/H2O2-mediated oxidation, the formation of melanin-like pigments from L-DOPA was evaluated. The effects of the various reaction conditions on the efficiency of the reaction and the physic-chemical properties of the pigments generated ...
Koen, Vercruysse, Koen Vercruysse
core +1 more source
Advanced Functional Materials, EarlyView.We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim +6 more
wiley +1 more source
Evidence of
Journal of Biomedical Science, 2010 Background l-Dopa has been used for Parkinson's disease management for a long time. However, its wide variety in the rate and the extent of absorption remained challenge in designing suitable therapeutic regime.
Wang Chun-Li +5 more
doaj +1 more source
Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson’s disease: a dose-finding study
Brain : a journal of neurology, 2015 See Bezard and Carta for a scientific commentary on this article (doi:10.1093/brain/awu407). In a double-blind placebo-controlled study, Svenningsson et al.
P. Svenningsson +8 more
semanticscholar +1 more source
Biodegradable and Biocompatible Functional Polymers for Biomedical Applications
Advanced Functional Materials, EarlyView.Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han +5 more
wiley +1 more source
MOESM1 of 3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of l-DOPA
, 2016 Additional file 1: Fig. S1. Levels of GDNF (A) or bFGF (B) in GCM of striatal astrocytes after the treatment with methyl-l-DOPA (25 or 50 µM) and/or 3-OMD (10 or 100 µM) for 24 h. Data are mean ± SEM (n = 6). **p
Masato Asanuma (420841) +1 more
core +1 more source