Results 81 to 90 of about 101,529 (354)

Keratin–Melanin Complexation Enables Robust, Delamination‐Resistant Feather‐Inspired Structural Color Coatings for Flexible and Curved Substrates

Advanced Materials Interfaces, EarlyView.
Providing mechanically robust structural color coating technology inspired by cooperative interactions in nature. The spatial arrangement of melanin particles within the keratin matrix generates angle‐independent structural colors. Diverse functional groups in keratin and melanin contribute to interparticle and substrate adhesion, resulting in the ...
Taisei Harada, Yui Maejima, Ryota Iwamori, Hideyuki Mitomo, Hirotoshi Tamayama, Shin‐ichi Takeda, Daisuke Unabara, Tasuku Hamaguchi, Koji Yonekura, Gen Morimoto, Hiroshi Fudouzi, Keiki Kishikawa, Michinari Kohri   +12 more
wiley   +1 more source

The Cardiovascular Actions of DOPA Mediated by the Gene Product of ocular albinism 1

Journal of Pharmacological Sciences, 2014
l-3,4-Dihydroxyphenylalanine (DOPA) is the metabolic precursor of dopamine, and the single most effective agent in the treatment of Parkinson’s disease.
Yoshio Goshima, Fumio Nakamura, Daiki Masukawa, Sandy Chen, Motokazu Koga   +4 more
doaj   +1 more source

Glial activation is associated with l-DOPA induced dyskinesia and blocked by a nitric oxide synthase inhibitor in a rat model of Parkinson's disease.

Neurobiology of Disease, 2015
l-3, 4-dihydroxyphenylalanine (L-DOPA) is the most effective treatment for Parkinson's disease but can induce debilitating abnormal involuntary movements (dyskinesia).
M. Bortolanza, Roberta Cavalcanti-Kiwiatkoski, F. E. Padovan-Neto, C. A. da-Silva, M. Mitkovski, R. Raisman-Vozari, E. Del-Bel   +6 more
semanticscholar   +1 more source

Turning Water Into a Tool: From Degradation Pathways to Functional Engineering in Halide Perovskites

Advanced Materials Technologies, EarlyView.
Water exhibits a threshold‐dependent dual role in lead halide perovskites, acting either as a degradation trigger or as a powerful tool for defect passivation, recrystallization, and structural engineering. This review discusses how controlled water‐mediated interactions govern stability, dimensionality, and optoelectronic performance, providing ...
Raphaella T. S. Gonçalves, Gabriela O. Gera, Aryane Tofanello, Jose A. Souza, Andre L. M. Freitas   +4 more
wiley   +1 more source

Mining Retrospective Data for Virtual Prospective Drug Repurposing: L-DOPA and Age-related Macular Degeneration

American Journal of Medicine, 2015
BACKGROUND Age-related macular degeneration (AMD) is a leading cause of visual loss among the elderly. A key cell type involved in AMD, the retinal pigment epithelium, expresses a G protein–coupled receptor that, in response to its ligand, L-DOPA, up ...
PhD Murray H. Brilliant, MD Kamyar Vaziri, MD c Thomas B. Connor Jr., M. M. B. Stephen G Schwartz, PhD Joseph J. Carroll, P. M. E. Catherine A. McCarty, PhD Steven J. Schrodi, PhD Scott J. Hebbring, MD Krishna S. Kishor, MD Harry W. Flynn Jr., MD f Andrew A. Moshfeghi, MD Darius M. Moshfeghi, PhD M. Elizabeth Fini, PhD Brian S. McKay   +13 more
semanticscholar   +1 more source

Multifunctional Adhesive Hydrogel for Rapid Cardiac Hemostasis and Antibacterial Protection

Advanced Materials Technologies, EarlyView.
A multifunctional polyacrylamide/gelatin/tannic acid hydrogel (PGT) is presented for rapid cardiac hemostasis under wet, dynamic conditions. Surface tannic acid coating enables instantaneous wet adhesion, accelerates coagulation, and confers antibacterial activity within a single platform.
Seoha Kim, Kaeun Chae, Inseon Kim, Kye Il Joo, Chang Sup Kim, Seunghun S. Lee   +5 more
wiley   +1 more source

L-Dopa and the albino riddle: content of L-Dopa in the developing retina of pigmented and albino mice. [PDF]

PLoS ONE, 2013
The absence or deficiency of melanin as in albinos, has detrimental effects on retinal development that include aberrant axonal projections from eye to brain and impaired vision. In pigmented retinal pigment epithelium (RPE), dihydroxyphenalanine (L-Dopa)
Suzanne Roffler-Tarlov, Jin Hong Liu, Elena N Naumova, Maria Margarita Bernal-Ayala, Carol A Mason   +4 more
doaj   +1 more source

Dopa-responsive dystonia

Vojnosanitetski pregled, 2009
Backgrround/Aim. Dystonia is considered to be a prolonged involuntary contractions of the muscles leading to twisting, repetitive movements or irregular postures. Etiologically, it could be classified as primary and secondary dystonia. Dopa-responsive dystonia (DRD) belongs to a group of primary dystonia.
Gordana Djuric, Marina Svetel, Eleonora Dzoljic, Vladimir Kostic   +3 more
openaire   +3 more sources

Iron‐Mediated Release of Aged Dissolved Organic Carbon From Waterlogged Peatland Under Warming

Advanced Science, EarlyView.
This study conducts a five‐year in situ warming experiment in high‐altitude peatlands to examine dissolved organic carbon (DOC) release. The study shows that warming promotes the release of plant‐derived modern DOC in drained peatlands, but amplifies aquatic export of century‐old DOC from waterlogged peatlands via Fe‐mediated DOC mobilization—a ...
Guohua Dai, Zhiying Yang, Zongguang Liu, Wanjia Hu, Lixiao Ma, Enze Kang, Wanqing Luo, Yunpeng Zhao, Chengzhu Liu, Juan Jia, Ting Liu, Chen He, Quan Shi, Jianliang Liu, Yongheng Gao, Huai Chen, Hailong Zhang, Meixun Zhao, Xiaojuan Feng   +18 more
wiley   +1 more source

L-DOPA-induced signaling pathways and neuroepigenetic mechanisms in experimental parkinsonism and dyskinesia

, 2014
In patients with Parkinson’s disease (PD), the restoration of depleted striatal dopamine by chronic administration of its precursor, L-DOPA, results in the emergence of debilitating involuntary movements.
Michael Feyder (18637498)
core   +1 more source