Specialized coding of sensory, motor, and cognitive variables in VTA dopamine neurons
Nature, 2019 There is increased appreciation that dopamine neurons in the midbrain respond not only to reward1 and reward-predicting cues1,2, but also to other variables such as the distance to reward3, movements4–9 and behavioural choices10,11. An important question
B. Engelhard +10 more
semanticscholar +1 more source
Assessment of the direct and indirect effects of MPP+ and dopamine on the human proteasome: implications for Parkinson's disease aetiology [PDF]
, 2008 Mitochondrial impairment, glutathione depletion and oxidative stress have been implicated in the pathogenesis of Parkinson’s disease (PD), linked recently to proteasomal dysfunction.
Beck, KE +5 more
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Journal of Pharmacological Sciences, 2012 Accumbal dopamine plays an important role in physiological responses and diseases such as schizophrenia, Parkinson’s disease, and depression. Since the nucleus accumbens contains different neurotransmitters, it is important to know how they interact with
Hiroko Ikeda +3 more
doaj +1 more source
Gray-matter volume, midbrain dopamine D2/D3 receptors and drug craving in methamphetamine users. [PDF]
, 2015 Dysfunction of the mesocorticolimbic system has a critical role in clinical features of addiction. Despite evidence suggesting that midbrain dopamine receptors influence amphetamine-induced dopamine release and that dopamine is involved in ...
Dean, AC +5 more
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Normal Uterus and Ovary in the Indonesian Population: A Comprehensive Analysis
Women's Health ReportsObjective: This research seeks to establish comprehensive baseline data on the normal anatomical features of the uterus and ovaries in a cohort of healthy Indonesian subjects. Methods: This research was a retrospective study employing 500 ultrasonography
Andi Darma Putra +4 more
doaj +1 more source
European Journal of Histochemistry, 2014 Dopamine D1 and D2 receptor immunohistochemistry and Golgi techniques were used to study the structure of the adult rat arcuate-median eminence complex, and determine the distribution of the dopamine D1 and D2 receptor immunoreactivities therein ...
W. Romero-Fernandez +7 more
doaj +1 more source
Heterogeneity of dopamine release sites in health and degeneration
Neurobiology of Disease, 2020 Despite comprising only ~ 0.001% of all neurons in the human brain, ventral midbrain dopamine neurons exert a profound influence on human behavior and cognition.
Joseph J. Lebowitz, Habibeh Khoshbouei
doaj +1 more source
Dopamine-modulated dynamic cell assemblies generated by the GABAergic striatal microcircuit [PDF]
, 2009 The striatum, the principal input structure of the basal ganglia, is crucial to both motor control and learning. It receives convergent input from all over the neocortex, hippocampal formation, amygdala and thalamus, and is the primary recipient of ...
Alexander +92 more
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Testosterone induces molecular changes in dopamine signaling pathway molecules in the adolescent male rat nigrostriatal pathway. [PDF]
PLoS ONE, 2014 Adolescent males have an increased risk of developing schizophrenia, implicating testosterone in the precipitation of dopamine-related psychopathology.
Tertia D Purves-Tyson +5 more
doaj +1 more source
The Dopaminergic Midbrain Encodes the Expected Certainty about Desired Outcomes [PDF]
, 2014 Dopamine plays a key role in learning; however, its exact function in decision making and choice remains unclear. Recently, we proposed a generic model based on active (Bayesian) inference wherein dopamine encodes the precision of beliefs about optimal ...
Dolan, Ray +4 more
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