Results 61 to 70 of about 506,450 (362)
Dopamine promotes cognitive effort by biasing the benefits versus costs of cognitive work
Science, 2019 Responsible use of psychostimulants Psychostimulants have a place in the therapy of attentional disorders. However, they are also widely used off-label to enhance cognitive performance, and their mechanisms of action remain elusive.
A. Westbrook +7 more
semanticscholar +1 more source
Dopamine Receptor Subtypes, Physiology and Pharmacology: New Ligands and Concepts in Schizophrenia
Frontiers in Pharmacology, 2020 Dopamine receptors are widely distributed within the brain where they play critical modulator roles on motor functions, motivation and drive, as well as cognition.
J. Martel, Silvia Gatti McArthur
semanticscholar +1 more source
Dopamine and Dopamine-Related Ligands Can Bind Not Only to Dopamine Receptors
Life, 2022 The dopaminergic system is one of the most important neurotransmitter systems in the central nervous system (CNS). It acts mainly by activation of the D1-like receptor family at the target cell. Additionally, fine-tuning of the signal is achieved via pre-synaptic modulation by the D2-like receptor family.
openaire +3 more sources
Direct Ink Writing of Conductive Hydrogels
Advanced Functional Materials, EarlyView.This review examines the use of direct ink writing (DIW) for fabricating conductive hydrogels with customizable 3D structures. It outlines the rheological requirements for successful DIW, followed by an exploration of the materials and ink formulations used to impart electronic and/or ionic conductivity to hydrogels while maintaining printability ...
Monica Ho +6 more
wiley +1 more source
TRPC4 ion channel protein is selectively expressed in a subpopulation of dopamine neurons in the ventral tegmental area [PDF]
, 2012 The nonselective cation channel TRPC4 has been shown to be present in high abundance in the corticolimbic regions of the brain and play a pivotal role in modulating cellular excitability due to their involvement in intracellular Ca2+ regulation. Recently we reported their involvement in socialization and regulating anxiety-like behaviors in rats. Given
arxiv +1 more source
Mean-field modeling of the basal ganglia-thalamocortical system. I. Firing rates in healthy and parkinsonian states [PDF]
J. Theor. Biol. 257: 642-663 (2009), 2018 Parkinsonism leads to various electrophysiological changes in the basal ganglia-thalamocortical system (BGTCS), often including elevated discharge rates of the subthalamic nucleus (STN) and the output nuclei, and reduced activity of the globus pallidus external segment (GPe).
arxiv +1 more source
Advanced Functional Materials, EarlyView.Effective electron transfer and stable enzyme immobilization, both between enzymes and host electrodes as well as between adjacent enzymes, are crucial for optimizing the biofuel cell (BFC) performance. Recently, efforts have focused on integrating these strategies with porous host electrodes.
Junha Pak +3 more
wiley +1 more source
Neurobiology of Disease, 2015 The dopamine transporter is a key protein responsible for regulating dopamine homeostasis. Its function is to transport dopamine from the extracellular space into the presynaptic neuron. Studies have suggested that accumulation of dopamine in the cytosol
S.T. Masoud +16 more
doaj
Frontiers in Psychiatry, 2011 Accumbal glycine modulates basal and ethanol-induced dopamine levels in the nucleus accumbens (nAc) as well as voluntary ethanol consumption. Also, systemic administration of the glycine transporter-1 inhibitor Org25935 elevates dopamine levels in nAc ...
Helga eHöifödt Lidö +4 more
doaj +1 more source
STRUCTURE OF THE D2 DOPAMINE RECEPTOR BOUND TO THE ATYPICAL ANTIPSYCHOTIC DRUG RISPERIDONE
Nature, 2018 Dopamine is a neurotransmitter that has been implicated in processes as diverse as reward, addiction, control of coordinated movement, metabolism and hormonal secretion.
Sheng Wang +5 more
semanticscholar +1 more source