Dopamine modulation via memristive schematic [PDF]
arXiv, 2017 In this technical report we present novel results of the dopamine neuromodulation inspired modulation of a polyaniline (PANI) memristive device excitatory learning STDP. Results presented in this work are of two experiments setup computer simulation and physical prototype experiments.
arxiv
Osteocyte-Driven Downregulation of Snail Restrains Effects of Drd2 Inhibitors on Mammary Tumor Cells [PDF]
, 2018 While bone is a frequent target of breast cancer-associated metastasis, little is known about the effects of tumor-bone interactions on the efficacy of tumor-suppressing agents.
Chen, Andy +8 more
core +1 more source
Drug-Induced Plasticity Contributing to Heightened Relapse Susceptibility: Neurochemical Changes and Augmented Reinstatement in High-Intake Rats [PDF]
, 2010 A key in understanding the neurobiology of addiction and developing effective pharmacotherapies is revealing drug-induced plasticity that results in heightened relapse susceptibility.
Baker, David A. +5 more
core +1 more source
Tetraspanin (TSP-17) Protects Dopaminergic Neurons against 6-OHDA-Induced Neurodegeneration in C. elegans [PDF]
, 2014 Parkinson's disease (PD), the second most prevalent neurodegenerative disease after Alzheimer's disease, is linked to the gradual loss of dopaminergic neurons in the substantia nigra.
A Garcia-Espana +75 more
core +4 more sources
Nature Methods, 2018 The genetically encoded sensor dLight1 reports dopamine release in culture, slices and behaving mice.
openaire +2 more sources
Chronic cocaine enhances release of neuroprotective amino acid taurine: a microdialysis study [PDF]
, 2008 Cocaine inhibits high-affinity neurotransmitter uptake at the presynaptic nerve terminals to increase synaptic levels of dopamine, norepinephrine and serotonin^1^. This increase of synaptic dopamine may cause neurotoxicity^2,3^.
Eitan Freedman +5 more
core +1 more source
Dopamine receptors gene expression in male rat hippocampus after administration of MDMA (Ecstasy) [La Expresión Génica de Receptores de Dopamina en el Hipocampo de Ratas Macho Después de la Administración de MDMA (Éxtasis)] [PDF]
, 2015 Ecstasy is one of the most popular amusing drugs among young people. Documents indicate some effects of Ecstasy on hippocampus and close relations between dopaminergic functions with reward learning. Therefore, the aim of this study was evaluation of the
Kamran, H. +3 more
core
GM1 Ganglioside Modifies α-Synuclein Toxicity and is Neuroprotective in a Rat α-Synuclein Model of Parkinson\u27s Disease. [PDF]
, 2019 While GM1 may interact with α-synuclein in vitro to inhibit aggregation, the ability of GM1 to protect against α-synuclein toxicity in vivo has not been investigated.
Aras, Radha +5 more
core +1 more source
Dopamine: A Research Framework for Deep Reinforcement Learning [PDF]
arXiv, 2018 Deep reinforcement learning (deep RL) research has grown significantly in recent years. A number of software offerings now exist that provide stable, comprehensive implementations for benchmarking. At the same time, recent deep RL research has become more diverse in its goals.
arxiv