Results 11 to 20 of about 278,985 (182)

Neuroprotection by dopamine agonists [PDF]

open access: yesJournal of neural transmission. Supplementum, 1994
Research on Parkinson's disease has led to new hypotheses concerning the mechanisms of neurodegeneration and to the development of neuroprotective agents. Recent findings of impaired mitochondrial function, altered iron metabolism and increased lipid peroxidation in the substantia nigra of parkinsonian patients emphasize the significance of oxidative ...
Lange, K. W.   +5 more
openaire   +4 more sources

Dopamine agonists for restless legs syndrome 

open access: yesAdvances in Clinical Neuroscience & Rehabilitation
Restless Legs Syndrome (RLS) is a common neurological disorder characterised by an uncontrollable urge to move the legs. Dopamine agonists are widely used as first or second-line treatments for RLS due to their efficiency in alleviating the symptoms of ...
Pran Phakdeekitcharoen, Michael J Keogh
doaj   +2 more sources

Dopamine Agonists and Pathologic Behaviors [PDF]

open access: yesParkinson's Disease, 2012
The dopamine agonists ropinirole and pramipexole exhibit highly specific affinity for the cerebral dopamine D3 receptor. Use of these medications in Parkinson’s disease has been complicated by the emergence of pathologic behavioral patterns such as ...
Brendan J. Kelley   +2 more
doaj   +3 more sources

Cost-effectiveness of dopamine agonists and monoamine oxidase B inhibitors in Parkinson’s disease [PDF]

open access: yes, 2021
Background: The PD MED study reported small but persistent benefits in patient‐rated mobility scores and quality of life from initiating therapy with levodopa compared with levodopa‐sparing therapies in early Parkinson's disease (PD).
Emma McIntosh   +28 more
core   +7 more sources

Dopamine genetic risk score predicts impulse control behaviors in Parkinson’s disease

open access: yesClinical Parkinsonism & Related Disorders, 2021
Introduction: Up to 40% of Parkinson’s disease patients taking dopamine agonist medication develop impulse control behaviors which can have severe negative consequences.
Alison Hall   +5 more
doaj   +1 more source

Observations on sleep-disordered breathing in idiopathic Parkinson's disease. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: This study has two main goals: 1.) to determine the potential influence of dopaminergic drugs on sleep-disordered breathing (SDB) in Parkinson's disease (PD) and 2.) to elucidate whether NREM and REM sleep differentially impact SDB severity ...
Philipp O Valko   +4 more
doaj   +1 more source

Resistance to dopamine agonists in the treatment of prolactinomas: diagnostic criteria, mechanisms and ways to overcome it

open access: yesAlʹmanah Kliničeskoj Mediciny, 2023
The priority treatment approach for prolactinomas is therapy with dopamine agonists, which allows for elimination of clinical symptoms, normalization of prolactin levels, reduction of the adenoma size and prevention of metabolic abnormalities in the ...
Irena A. Ilovayskaya, Gulnar R. Vagapova
doaj   +1 more source

Response of Macroprolactinemia to Dopamine Agonists

open access: yesEndocrinology Research and Practice, 2008
Macroprolactinemia, defined as hyperprolactinemia with a predominance of the big big prolactin (macroprolactin) isoform, is considered idiopathic and poorly symptomatic. Although macroprolactinemia has been considered to be a cause of apparent resistance
Gonca Tamer   +3 more
doaj   +3 more sources

Dopamine agonists and antipsychotics [PDF]

open access: yesEuropean Journal of Endocrinology, 2020
There can potentially be a number of clinical interactions that could adversely affect patient outcomes in a patient with a prolactinoma and psychiatric disease that might require antipsychotic and dopamine agonist treatment. Dopamine agonists stimulate the dopamine D2 receptor, resulting in a decrease in prolactin (PRL) levels and in prolactinoma size
openaire   +2 more sources

Impulsivity in Patients with Parkinson’s Disease [PDF]

open access: yesJournal of Biomedical & Clinical Research, 2017
In recent years focus has been increasingly placed on impulse control disorders (ICDs) in patients with Parkinson’s disease (PD). ICDs include pathological attraction to gambling, compulsive shopping, compulsive eating and compulsive sexual behaviour and
Rumyana Kuzmanova   +2 more
doaj   +3 more sources

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