Dopamine agonists for restless legs syndrome
Advances in Clinical Neuroscience & RehabilitationRestless Legs Syndrome (RLS) is a common neurological disorder characterised by an uncontrollable urge to move the legs. Dopamine agonists are widely used as first or second-line treatments for RLS due to their efficiency in alleviating the symptoms of ...
Pran Phakdeekitcharoen, Michael J Keogh
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Receptores de dopamina y heterómeros de receptores de dopamina en la modulación de la neurotransmisión [PDF]
, 2012 [spa] La mayoría de los ligandos de GPCR que actúan como agonistas, antagonistas o agonistas inversos, se unen al mismo dominio del receptor reconocido por los agonistas endógenos, es decir, el lugar de unión ortostérico.
González González, Sergio
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Impulsivity in Patients with Parkinson’s Disease [PDF]
Journal of Biomedical & Clinical Research, 2017 In recent years focus has been increasingly placed on impulse control disorders (ICDs) in patients with Parkinson’s disease (PD). ICDs include pathological attraction to gambling, compulsive shopping, compulsive eating and compulsive sexual behaviour and
Rumyana Kuzmanova +2 more
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Heterómeros de receptores de dopamina. Nuevos mecanismos para la regulación de la transmisión dopaminérgica [PDF]
, 2012 [spa] El Objetivo General de esta Tesis ha sido investigar la formación y función de heterómeros entre receptores de dopamina y otros receptores que puedan estar implicados en la regulación de la transmisión dopaminérgica, como receptores de galanina ...
Moreno Guillén, Estefanía
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Predictors of dopamine agonist resistance in prolactinoma patients
BMC Endocrine Disorders, 2020 Background Surgical resection of prolactinomas resistant to dopamine agonists is frequently incomplete due to fibrotic changes of the tumour under pharmacological therapy. In order to identify a subgroup of patients who may benefit from early surgery, we
Elle Vermeulen +6 more
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Disrupted dopamine transmission and the emergence of exaggerated beta oscillations in subthalamic nucleus and cerebral cortex [PDF]
, 2008 In the subthalamic nucleus (STN) of Parkinson’s disease (PD) patients, a pronounced synchronization of oscillatory activity at beta frequencies (15–30 Hz) accompanies movement difficulties.
Sharott, A +7 more
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Pharmacology of dopamine agonists in the treatment of Parkinson's disease
, 2002 There is now increasing use of dopamine agonists as effective early monotherapy in the treatment of Parkinson's disease (PD). Dopamine agonists can induce an antiparkinsonian effect through actions on either D-1-like or D-2-like dopamine receptors, and ...
Jenner, P
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The effects of the dopamine agonist rotigotine on hemispatial neglect following stroke [PDF]
, 2012 Hemispatial neglect following right-hemisphere stroke is a common and disabling disorder, for which there is currently no effective pharmacological treatment. Dopamine agonists have been shown to play a role in selective attention and working memory, two
Kulinskaya, Elena +26 more
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Clinical Aspects and Management of Levodopa-Induced Dyskinesia
Parkinson's Disease, 2012 In Parkinson's disease, one of the most troublesome dilemmas is the treatment of levodopa-induced dyskinesia. After a few years, chronic treatment with levodopa is associated with the development of dyskinesias.
Nicola Tambasco +7 more
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Highly potent, selective acylguanidine-type histamine H2 receptor agonists: synthesis and structure-activity relationships [PDF]
, 2008 Potent and selective histamine H2 receptor (H2R) agonists are valuable pharmacological tools and might be of therapeutic value as drugs, for example in the treatment of severe congestive heart failure.
Kraus, Anja
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