Results 21 to 30 of about 58,665 (272)

Clinical Aspects and Management of Levodopa-Induced Dyskinesia

open access: yesParkinson's Disease, 2012
In Parkinson's disease, one of the most troublesome dilemmas is the treatment of levodopa-induced dyskinesia. After a few years, chronic treatment with levodopa is associated with the development of dyskinesias.
Nicola Tambasco   +7 more
doaj   +1 more source

Dopamine agonists and antipsychotics [PDF]

open access: yesEuropean Journal of Endocrinology, 2020
There can potentially be a number of clinical interactions that could adversely affect patient outcomes in a patient with a prolactinoma and psychiatric disease that might require antipsychotic and dopamine agonist treatment. Dopamine agonists stimulate the dopamine D2 receptor, resulting in a decrease in prolactin (PRL) levels and in prolactinoma size
openaire   +2 more sources

A quantum chemical approach representing a new perspective concerning agonist and antagonist drugs in the context of schizophrenia and Parkinson's disease.

open access: yesPLoS ONE, 2019
Schizophrenia and Parkinson's disease can be controlled with dopamine antagonists and agonists. In order to improve the understanding of the reaction mechanism of these drugs, in this investigation we present a quantum chemical study of 20 antagonists ...
Ana Martínez   +2 more
doaj   +1 more source

Treatment of hyperprolactinemia: a systematic review and meta-analysis

open access: yesSystematic Reviews, 2012
Background Hyperprolactinemia is a common endocrine disorder that can be associated with significant morbidity. We conducted a systematic review and meta-analyses of outcomes of hyperprolactinemic patients, including microadenomas and macroadenomas, to ...
Wang Amy T   +14 more
doaj   +1 more source

Recurrent Priapism From Cabergoline and Bromocriptine in a Hypogonadal Man With Prolactinoma

open access: yesJournal of Investigative Medicine High Impact Case Reports, 2021
Dopamine agonists are generally well tolerated and represent the first-line therapy for prolactinomas. We report a case of a 20-year-old man with a macroprolactinoma who developed recurrent priapism with cabergoline and bromocriptine.
Lakshmi P. Menon MD, Wedad Rahman MD
doaj   +1 more source

Pyridoxine induces glutathione synthesis via PKM2-mediated Nrf2 transactivation and confers neuroprotection

open access: yesNature Communications, 2020
Dopamine agonists increase brain glutathione levels. Here the authors identify noncanonical signalling by Nrf2 as a potential mechanism for the neuroprotective effects of dopamine D2 receptor activation.
Yao Wei   +11 more
doaj   +1 more source

Dopamine Receptor Subtypes, Physiology and Pharmacology: New Ligands and Concepts in Schizophrenia

open access: yesFrontiers in Pharmacology, 2020
Dopamine receptors are widely distributed within the brain where they play critical modulator roles on motor functions, motivation and drive, as well as cognition.
Jean Claude Martel   +1 more
doaj   +1 more source

Neuropsychiatric and metabolic aspects of dopaminergic therapy: perspectives from an endocrinologist and a psychiatrist

open access: yesEndocrine Connections, 2018
The dopaminergic treatment represents the primary treatment in prolactinomas, which are the most common pituitary adenomas and account for about 40% of all pituitary tumours with an annual incidence of six to ten cases per million population.
Anastasia P Athanasoulia-Kaspar   +2 more
doaj   +1 more source

TAAR1 in Addiction: Looking Beyond the Tip of the Iceberg

open access: yesFrontiers in Pharmacology, 2018
Trace-amine associated receptor 1 (TAAR1) is the best-characterized member of the family of TAARs. TAAR1 is broadly expressed in the brain, especially within the monoaminergic systems.
Jian-Feng Liu, Jian-Feng Liu, Jun-Xu Li
doaj   +1 more source

Progress in the study of Dopamine Receptor Agonists for Brain Protection after Ischemic Brain Injury

open access: yesZhongguo cuzhong zazhi
: Ischemic brain injury comprises 87% of all brain injuries and typically results in severe functional impairments. Dopamine, the most abundant catecholamine neurotransmitter in the brain, is intimately linked with autonomous movement, emotion, sleep ...
ZHANG Linyao1, LIU Lixu1,2
doaj   +1 more source

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