Managing Dystonia in Partington Syndrome
Abstract Background Bilateral focal hand dystonia is an almost pathognomonic sign of Partington syndrome, frequently accompanied by intellectual disability and oromotor dyspraxia. However, a few studies have focused on the treatment of this focal dystonia, making patient management uncertain.
Emilie Pichon +13 more
wiley +1 more source
System-level hypothesis of dopamine imbalance in early multiple sclerosis. [PDF]
Caligiore D, Schirripa A, Biggio M.
europepmc +1 more source
Abstract Background Research on Parkinson's disease (PD) heterogeneity may inform clinical prognosis. There is currently no fully validated PD subtype classification system. Objectives We aimed at assessing the prognostic relevance of a data‐driven PD subtype classification system.
Deepa Dash +7 more
wiley +1 more source
Optogenetic stimulation of midbrain dopaminergic neurons rescues hippocampal synaptic plasticity deficits in a mouse model of Alzheimer's disease. [PDF]
Ficchì S +11 more
europepmc +1 more source
High Cerebrospinal DOPA Decarboxylase Level Predicts Cognitive Decline in Parkinson's Disease
Abstract Background DOPA decarboxylase (DDC) in cerebrospinal fluid (CSF) is an emerging Parkinson's disease (PD) biomarker, but its association with nonmotor symptoms is unclear. Objectives We aimed to determine if baseline DDC was associated with future cognitive decline in PD.
Andrea Sturchio +7 more
wiley +1 more source
Strikingly different neurotransmitter release strategies in dopaminergic subclasses. [PDF]
Dorrego-Rivas A +7 more
europepmc +1 more source
Abstract Background Findings are contradictory regarding changes in the incidence and prevalence of Parkinson's disease (PD) over time; data for other parkinsonian disorders are rare. Objectives To analyze temporal trends in the incidence and prevalence of eight parkinsonisms (PD, MSA, PSP, CBS, DLB, vascular parkinsonism, drug‐induced parkinsonism ...
Sacha E. Gandhi +7 more
wiley +1 more source
Effects of dopaminergic medication on upper limb motor function, strength and hand dexterity in people with Parkinson's disease. [PDF]
Alaei P, Wile DJ, Jakobi JM.
europepmc +1 more source
Single-Cell Profiling Identifies Reward Behavior-Related Neurons and Alterations in the Ventral Tegmental Area Based on <i>Arvcf</i>-Knockout Mouse Model. [PDF]
Zhang M +6 more
europepmc +1 more source

