Results 221 to 230 of about 835,318 (379)

Control of neuronal diversity by the floor plate: Contact-mediated induction of midbrain dopaminergic neurons

, 1995
Mary Hynes, Kris Poulsen, Marc Tessier‐Lavigne, Arnon Rosenthal   +3 more
openalex   +1 more source

Fate of Midbrain Dopaminergic Neurons Controlled by the Engrailed Genes [PDF]

, 2001
Horst H. Simon, Harald Saueressig, Wolfgang Wurst, Martyn Goulding, Dennis D.M. O’Leary   +4 more
openalex   +1 more source

Selective Effects of Substantia Nigra and Locus Coeruleus Degeneration on Cognition in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background The substantia nigra (SN) and locus coeruleus (LC) are among the first brain regions to degenerate in Parkinson's disease (PD). This has important implications for early cognitive deficits because these nuclei are sources of ascending neuromodulators (i.e., dopamine and noradrenaline) that support various cognitive functions such as
Sophie Sun, Victoria Madge, Jelena Djordjevic, Jean‐François Gagnon, D. Louis Collins, Alain Dagher, Madeleine Sharp   +6 more
wiley   +1 more source

SIAH proteins regulate the degradation and intra‐mitochondrial aggregation of PINK1: Implications for mitochondrial pathology in Parkinson's disease

Aging Cell, Volume 21, Issue 12, December 2022., 2022
Our study reports that SIAH3 is increased in PD brains. We also found that SIAH3, along with PINK1, is aggregated in the mitochondria of PD brains. The intra‐mitochondrial aggregation of SIAH3 and PINK1 inactivates PINK1, depolarizes the mitochondria, and leads to neuronal death.
Fatimah Abd Elghani, Hazem Safory, Haya Hamza, Mor Savyon, Malik Farhoud, Michal Toren‐Hershoviz, Zagorka Vitic, Kirsten Ebanks, Vered Shani, Sleman Bisharat, Lihi Shaulov, Claude Brodski, Zhiyin Song, Rina Bandopadhyay, Simone Engelender   +14 more
wiley   +1 more source

Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease? [PDF]

, 2001
Andréas Hartmann, Patrick P. Michel, Jean‐Denis Troadec, Annick Mouatt‐Prigent, Baptiste Faucheux, Merle Ruberg, Y. Agid, Étienne C. Hirsch   +7 more
openalex   +1 more source

Patients with Allan‐Herndon‐Dudley Syndrome (MCT8 Deficiency) Display Symptoms of Parkinsonism in Childhood and Respond to Levodopa/Carbidopa Treatment

Movement Disorders, EarlyView.
Abstract Background Patients with mutations in the monocarboxylate transporter 8 (MCT8, SLC16A2) suffer from X‐linked recessive Allan‐Herndon‐Dudley syndrome (AHDS), which is characterized by developmental delay and a severe movement disorder. Current trials using thyroid hormone derivatives to overcome the transporter defect have failed to achieve ...
Nina‐Maria Wilpert, Angela L. Hewitt, Roser Pons, Marie‐Thérèse Henke, Andrea Dell'Orco, Martin Bauer, Christiane Grolik, Stephan Menz, Monika Wahle, Annika Zink, Alessandro Prigione, Christina Reinauer, Catharina Lange, Christian Furth, Knut Brockmann, Sabine Jung‐Klawitter, Stine Christ, Angela M. Kaindl, Anna Tietze, Heiko Krude, Thomas Opladen, Markus Schuelke   +21 more
wiley   +1 more source

Repetitive prefrontal tDCS activates VTA dopaminergic neurons, resulting in attenuation of Alzheimer's Disease-like deficits in Tg2576 mice. [PDF]

Alzheimers Res Ther
De Paolis ML, Loffredo G, Krashia P, La Barbera L, Nobili A, Cauzzi E, Babicola L, Di Segni M, Coccurello R, Puglisi-Allegra S, Latagliata EC, D'Amelio M.   +11 more
europepmc   +1 more source

Tuning pacemaker frequency of individual dopaminergic neurons by Kv4.3L and KChip3.1 transcription [PDF]

, 2001
Birgit Liss, Oliver Franz, Sabine Sewing, Ralf Bruns, Henrike Neuhoff, Jochen Roeper   +5 more
openalex   +1 more source

Finely Tuned γ Tracks Medication Cycles in Parkinson's Disease: An Ambulatory Brain‐Sense Study

Movement Disorders, EarlyView.
Abstract Background Novel commercial brain‐sense neurostimulators enable us to contextualize brain activity with symptom and medication states in real‐life ambulatory settings in Parkinson's disease (PD). Although various candidate biomarkers have been proposed for adaptive deep brain stimulation (DBS), a comprehensive comparison of their ambulatory ...
Aaron Colombo, Elena Bernasconi, Laura Alva, Mario Sousa, Ines Debove, Andreas Nowacki, Camille Serquet, Katrin Petermann, T.A. Khoa Nguyen, Andreia D. Magalhães, Lenard Lachenmayer, Julia Waskönig, Tobias Nef, Michael Schuepbach, Claudio Pollo, Paul Krack, Alberto Averna, Gerd Tinkhauser   +17 more
wiley   +1 more source

Postnatal Development of Dendritic Morphology and Action Potential Shape in Rat Substantia Nigra Dopaminergic Neurons. [PDF]

eNeuro
Moubarak E, Wernert F, Tell F, Goaillard JM.   +3 more
europepmc   +1 more source