Results 51 to 60 of about 1,331,644 (204)

Effects of Aerobic and Speed Training Versus Active Control on Repeated Sprint Ability and Measures of Self-confidence and Anxiety in Highly Trained Male Soccer Players

Sports Medicine - Open, 2023
Background While there is ample evidence on the effects of single-mode aerobic and speed training on physical fitness in soccer players, less is known on the combined effects of these exercise regimens on physical and psychological factors.
Walid Selmi, Raouf Hammami, Sofien Kasmi, Sonia Sehli, Haithem Rebai, Michael Duncan, Mokhtar Chtara, Urs Granacher   +7 more
doaj   +1 more source

Modeling of dose-response relationships. [PDF]

Environmental Health Perspectives, 1981
The main dose-response models for chronic toxicity are considered. For dichotomous response, the log probit, multi-hit, and multistage models are presented. For time-to-occurrence response, the log-normal and three variations of multistage models are presented. Finally, the Cornfield hockey-stick model is considered, and, for low-dose extrapolation, it
openaire   +2 more sources

Dose-response relationship and low dose extrapolatioin in chemical carcinogenesis [PDF]

, 2017
Data supporting various dose-response relationships in chemical carcinogenesis are summarized. General principles are derived to explain the relationships between exposure dose, DNA adduct level, induction of genetic changes, and tumor incidence.
Lutz, Werner K.
core  

Model Selection versus Model Averaging in Dose Finding Studies [PDF]

, 2015
Phase II dose finding studies in clinical drug development are typically conducted to adequately characterize the dose response relationship of a new drug.
Bornkamp, Björn, Bretz, Frank, Dette, Holger, Schorning, Kirsten   +3 more
core   +2 more sources

PET/MRI of Hepatic 90Y Microsphere Deposition Determines Individual Tumor Response. [PDF]

, 2016
PurposeThe purpose of our study is to determine if there is a relationship between dose deposition measured by PET/MRI and individual lesion response to yttrium-90 ((90)Y) microsphere radioembolization.Materials and methods26 patients undergoing lobar ...
Fowler, Kathryn J, Laforest, Richard, Maughan, Nichole M, Olsen, Jeffrey, Parikh, Parag J, Saad, Nael E, Sharma, Akash, Speirs, Christina K   +7 more
core   +2 more sources

Correlation between cardiometabolic index and stroke in middle-aged and older adults

Zhongguo linchuang yanjiu
Objective To explore the relationship between cardiac metabolic index (CMI) and stroke in middle-aged and elderly individuals based on a large sample cohort study. Methods Data were obtained from the China Health and Retirement Longitudinal Study (CHARLS)
YU Yang, SHA Ou
doaj   +1 more source

Gamma-glutamyltransferase and risk of hypertension:A systematic review and dose-response meta-analysis of prospective evidence [PDF]

, 2015
The objective of this review was to obtain a reliable estimate of the magnitude of the prospective association between gamma-glutamyltransferase (GGT) and risk of hypertension, and to characterize the nature of the dose-response relationship.
Apekey, Tanefa Antoinette, Cheung, Bernard M Y, Kunutsor, Setor K   +2 more
core   +2 more sources

A Review of the Dose Justification of Phase 3 Trials to Regulatory Authorities for Drugs Intended for the Treatment of Type 2 Diabetes in Europe

Frontiers in Pharmacology, 2021
Aims: Cardiovascular outcome trials with anti-diabetic drugs suggest that additional cardiovascular benefit can be achieved independent of improving glycaemic control.
Jeroen V. Koomen, Jeroen V. Koomen, Jasper Stevens, Margje H. Monster-Simons, Margje H. Monster-Simons, Hiddo J. L. Heerspink, Peter G. M. Mol, Peter G. M. Mol   +7 more
doaj   +1 more source

Dose-dependent inhibition of gastric injury by hydrogen in alkaline electrolyzed drinking water [PDF]

, 2014
BACKGROUND: Hydrogen has been reported to relieve damage in many disease models, and is a potential additive in drinking water to provide protective effects for patients as several clinical studies revealed.
Guodong Shang, Jinling Xue, Lingyan Hou, Natalia Velasquez, Wenjun Liu, Yasuhiro Saihara, Yoshinori Tanaka, Yun Lu   +7 more
core   +1 more source

Comparative effective dose of ciprofol and propofol in suppressing cardiovascular responses to tracheal intubation

Scientific Reports
Ciprofol, a novel γ-aminobutyric acid receptor agonist, outperforms propofol with minimal cardiovascular effects, higher potency, reduced injection pain, and a broader safety margin.
Min Liao, Xiao-Ru Wu, Jia-Ning Hu, Xing-Zhou Lin, Tang‑yuan‑meng Zhao, Hu Sun   +5 more
doaj   +1 more source