Dose-Response Relationships of RU 486
Clinical experience has indicated that the effects of RU 486 can be divided into dose-dependent and dose-independent effects. Examples of the dose-dependent effects include the antiglucocorticoid effects of RU 486, whereas pregnancy termination or dilatation of the cervix can be considered dose-independent with the various regimens tested so far ...
O, Heikinheimo, R, Kekkonen
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Fruit Flies Provide New Insights in Low-Radiation Background Biology at the INFN Underground Gran Sasso National Laboratory (LNGS) [PDF]
Deep underground laboratories (DULs) were originally created to host particle, astroparticle or nuclear physics experiments requiring a low-background environment with vastly reduced levels of cosmic-ray particle interference. More recently, the range of
Cenci, G. +5 more
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A U-shaped dose–response of carbohydrate–protein supplementation on rowing performance
Background and aimCo-ingestion of carbohydrate and protein supplement (CHO–PRO) is a common strategy to enhance endurance performance. However, the optimal dose–response relationship has not been established, which limits evidence-based nutritional ...
Xiangyu Wang, Xiangyu Wang, Hao Wu
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Western corn rootworm pyrethroid resistance confirmed by aerial application simulations of commercial insecticides [PDF]
The western corn rootworm (Diabrotica virgifera virgifera LeConte) (WCR) is a major insect pest of corn (Zea mays L.) in the United States (US) and is highly adaptable to multiple management tactics.
Fritz, Bradley K. +6 more
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Optimizing prediction of binge eating episodes : a comparison approach to test alternative conceptualizations of the affect regulation model [PDF]
Background : Although a wealth of studies have tested the link between negative mood states and likelihood of a subsequent binge eating episode, the assumption that this relationship follows a typical linear dose–response pattern (i.e., that risk ...
Austin,D +8 more
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Background preeclampsia (PE) remains a leading cause of maternal and perinatal morbidity and mortality worldwide. While metabolic and inflammatory factors are increasingly recognized in its pathogenesis, the clinical utility of composite biomarkers ...
Yuting Liang +9 more
doaj +1 more source
Characteristics of ADHD symptom response/remission in a clinical trial of methylphenidate extended release [PDF]
Clinical trials in attention-deficit/hyperactivity disorder (ADHD) have typically measured outcome using clinician ratings on the Attention-Deficit/Hyperactivity Disorder Rating Scale, Fourth Edition (ADHD-RS-IV) and the Clinical Global Impression ...
Adjei, Akwete L +5 more
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Objective: To prospectively determine the median effective dose (ED50) of propofol for inhibiting a response to laryngeal mask airway (LMA) insertion when combined with different doses of esketamine in female patients.
Yan-Jun Lin +4 more
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Influence of oxidative stress, diaphragm fatigue, and inspiratory muscle training on the plasma cytokine response to maximum sustainable voluntary ventilation [PDF]
The influence of oxidative stress, diaphragm fatigue, and inspiratory muscle training (IMT) on the cytokine response to maximum sustainable voluntary ventilation (MSVV) is unknown.
Brown PI +10 more
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Purpose Ciprofol has been investigated as a potential alternative to propofol for anesthesia because of its tendency to depress the respiratory and circulatory systems to a lesser extent and its association with less pain during injection.
Yu Zhang +4 more
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