Results 1 to 10 of about 2,157,984 (211)
Utilization of Bacteriophage phi6 for the Production of High-Quality Double-Stranded RNA Molecules
VirusesDouble-stranded RNA (dsRNA) molecules are mediators of RNA interference (RNAi) in eukaryotic cells. RNAi is a conserved mechanism of post-transcriptional silencing of genes cognate to the sequences of the applied dsRNA.
Alesia A. Levanova, Minna M. Poranen
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A phagocytic route for uptake of double-stranded RNA in RNAi. [PDF]
PLoS ONE, 2011 RNA interference (RNAi) has a range of physiological functions including as a defence mechanism against viruses. To protect uninfected cells in a multicellular organism, not only a cell-autonomous RNAi response is required but also a systemic one ...
João J E Rocha +3 more
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Application of Double-stranded RNA (dsRNA) Produced by E. coli HT115 (DE3) and Vector L4440 in Reverse Genetics Studies in Insects [PDF]
Journal of Genetic Resources, 2023 RNA interference is a cellular process for regulating gene expression by double-stranded RNA (dsRNA). In the past two decades, this cellular process has been used as a tool for the temporary knockdown of gene expression to study gene function in reverse ...
Roohollah Abbasi
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Frontiers in Microbiology, 2021 Here, we report a novel double-stranded RNA virus designated Colletotrichum liriopes partitivirus 1 (ClPV1) from the plant pathogenic fungus C. liriopes.
Jun Zi Zhu +7 more
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A Single RNaseIII Domain Protein from Entamoeba histolytica Has dsRNA Cleavage Activity and Can Help Mediate RNAi Gene Silencing in a Heterologous System. [PDF]
PLoS ONE, 2015 Dicer enzymes process double-stranded RNA (dsRNA) into small RNAs that target gene silencing through the RNA interference (RNAi) pathway. Dicer enzymes are complex, multi-domain RNaseIII proteins, however structural minimalism of this protein has ...
Justine M Pompey +2 more
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Biology Direct, 2007 Background It is generally believed that life first evolved from single-stranded RNA (ssRNA) that both stored genetic information and catalyzed the reactions required for self-replication. Presentation of the hypothesis By modeling early genome evolution
de Roos Albert DG
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Nature Communications, 2021 Mammalian reovirus (MRV) is a double-stranded RNA (dsRNA) virus that affects the gastrointestinal and respiratory tracts. Here, the authors present the 3.3 Å cryo-EM asymmetric reconstruction of transcribing MRV that reveals the organization of the dsRNA
Muchen Pan +5 more
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Primer-dependent and primer-independent initiation of double stranded RNA synthesis by purified Arabidopsis RNA-dependent RNA polymerases RDR2 and RDR6. [PDF]
PLoS ONE, 2015 Cellular RNA-dependent RNA polymerases (RDRs) are fundamental components of RNA silencing in plants and many other eukaryotes. In Arabidopsis thaliana genetic studies have demonstrated that RDR2 and RDR6 are involved in the synthesis of double stranded ...
Anthony Devert +5 more
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Frontiers in Plant Science, 2018 Double-stranded RNA (dsRNA) plays essential functions in many biological processes, including the activation of innate immune responses and RNA interference.
Baptiste Monsion +9 more
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MethodsX, 2023 Accurate genomic sequencing demands high-quality double-stranded RNA (dsRNA). Existing methods for dsRNA extraction from yeast, fungi, and plants primarily rely on cellulose, suitable only for small volume extractions, or the time-consuming lithium ...
Fernando M.H. Cardoso +4 more
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