Results 51 to 60 of about 1,047,229 (199)

Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET [PDF]

open access: yesNature Chemistry, 2014
The ability to introduce different biophysical probes into defined positions in target proteins will provide powerful approaches for interrogating protein structure, function and dynamics. However, methods for site-specifically incorporating multiple distinct unnatural amino acids are hampered by their low efficiency. Here we provide a general solution
Wang, Kaihang   +7 more
openaire   +4 more sources

Standard and Specialized Infant Formulas in Europe: Making, Marketing, and Health Outcomes [PDF]

open access: yes, 2019
Infant formulas are the only suitable substitute for human milk. The most common infant formulas are standard formulas based on cow's milk. In addition, there are formulas for infants showing signs and symptoms of intolerance and for clinical conditions ...
Corsello G   +3 more
core   +1 more source

Outstanding chain-extension effect and high UV resistance of polybutylene succinate containing amino-acid-modified layered double hydroxides

open access: yesBeilstein Journal of Nanotechnology, 2019
Polybutylene succinate (PBS) nanocomposite materials were prepared using a melt compounding process. The Mg2Al-based PBS nanocomposites, dispersed with inorganic–organic hybrid materials (layered double hydroxides, LDHs), were functionalized with the ...
Adam A. Marek   +6 more
doaj   +1 more source

Genomics and proteomics: a signal processor's tour [PDF]

open access: yes, 2004
The theory and methods of signal processing are becoming increasingly important in molecular biology. Digital filtering techniques, transform domain methods, and Markov models have played important roles in gene identification, biological sequence ...
Vaidyanathan, P. P.
core   +2 more sources

ATP-dependent polymerization dynamics of bacterial actin proteins involved in Spiroplasma swimming

open access: yesOpen Biology, 2022
MreB is a bacterial protein belonging to the actin superfamily. This protein polymerizes into an antiparallel double-stranded filament that determines cell shape by maintaining cell wall synthesis.
Daichi Takahashi   +5 more
doaj   +1 more source

Assisted evolution enables HIV-1 to overcome a high trim5α-imposed genetic barrier to rhesus macaque tropism [PDF]

open access: yes, 2013
Diversification of antiretroviral factors during host evolution has erected formidable barriers to cross-species retrovirus transmission. This phenomenon likely protects humans from infection by many modern retroviruses, but it has also impaired the ...
A Kuroishi   +75 more
core   +3 more sources

Crossing fitness valleys via double substitutions within codons

open access: yesBMC Biology, 2019
Background Single nucleotide substitutions in protein-coding genes can be divided into synonymous (S), with little fitness effect, and non-synonymous (N) ones that alter amino acids and thus generally have a greater effect.
Frida Belinky   +3 more
doaj   +1 more source

The role of amino acid metabolism alterations in acute ischemic stroke: From mechanism to application

open access: yesPharmacological Research
Acute ischemic stroke (AIS) is the most prevalent type of stroke, and due to its high incidence, disability rate, and mortality rate, it imposes a significant burden on the health care system.
Xiang-Ping Wang   +9 more
doaj   +1 more source

Comparison of effectiveness of tranexamic acid and epsilon-amino-caproic-acid in decreasing postoperative bleeding in off-pump CABG surgeries: A prospective, randomized, double-blind study

open access: yesAnnals of Cardiac Anaesthesia, 2020
Context: Off-pump coronary artery bypass graft (CABG) surgeries have been shown to have increased fibrinolysis due to tissue plasminogen activator release.
Swapnil Verma   +3 more
doaj   +1 more source

Aminosäuren – Leitlinie Parenterale Ernährung, Kapitel 4 [PDF]

open access: yes, 2009
Protein catabolism should be reduced and protein synthesis promoted with parenteral nutrion (PN). Amino acid (AA) solutions should always be infused with PN. Standard AA solutions are generally used, whereas specially adapted AA solutions may be required
Blumenstein, Irina Ursula   +4 more
core  

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