Genome Wide Transcriptome Analysis of Dendritic Cells Identifies Genes with Altered Expression in Psoriasis [PDF]
, 2013 Activation of dendritic cells by different pathogens induces the secretion of proinflammatory mediators resulting in local inflammation. Importantly, innate immunity must be properly controlled, as its continuous activation leads to the development of ...
Filkor, Katalin +6 more
core +16 more sources
Machine learning on thyroid disease: a review
Frontiers in Bioscience-Landmark, 2022 This study reviews the recent progress of machine learning for the early diagnosis of thyroid disease. Based on the results of this review, different machine learning methods would be appropriate for different types of data for the early diagnosis of ...
Kwang-Sig Lee, Hyuntae Park
doaj +1 more source
TIFAB accelerates MLL-AF9−Induced acute myeloid leukemia through upregulation of HOXA9
iScience, 2021 Summary: We previously showed stabilization of NIK−induced activation of NF-κB non-canonical signaling suppresses MLL-AF9−induced AML. In the current study, we demonstrate that deletion of NF-κB non-canonical RelB prevents the inhibitory effect of NIK ...
Jinming Zhao +10 more
doaj +1 more source
World Journal of Surgical Oncology, 2022 Purpose This study aimed at investigating miR-382-5p expression in tissues and cell lines with hepatocellular carcinoma (HCC), its effects on the invasion of HCC cells, and related mechanisms.
Bo Lv +3 more
doaj +1 more source
Molecules, 2020 Magnolol is a biologically active compound, isolated from the Chinese herb Magnolia, that regulates antiproliferative, anticancer, antiangiogenic and antimetastatic activities.
Seon Min Woo +2 more
doaj +1 more source
Upregulated wnt-11 and mir-21 expression trigger epithelial mesenchymal transition in aggressive prostate cancer cells [PDF]
, 2020 Prostate cancer (PCa) is the second-leading cause of cancer-related death among men. microRNAs have been identified as having potential roles in tumorigenesis.
Arisan, E.D. +15 more
core +1 more source
Moscatilin suppresses the inflammation from macrophages and T cells
Open Medicine, 2022 In this study, we aim to investigate moscatilin in alleviating symptoms of autoimmune liver disease (ALD) in a concanavalin A (ConA)-induced liver injury mouse model and elucidate the underlying mechanisms.
Zhang Ying +5 more
doaj +1 more source
SALL4 as an Epithelial-Mesenchymal Transition and Drug Resistance Inducer through the Regulation of c-Myc in Endometrial Cancer. [PDF]
PLoS ONE, 2015 SALL4 plays important roles in the development and progression of many cancers. However, the role and molecular mechanism of SALL4 in endometrial cancer remain elusive.
Lei Liu +5 more
doaj +1 more source
IFI35 is involved in the regulation of the radiosensitivity of colorectal cancer cells
Cancer Cell International, 2021 Background Interferon regulatory factor-1 (IRF1) affects the proliferation of colorectal cancer (CRC). Recombinant interferon inducible protein 35 (IFI35) participates in immune regulation and cell proliferation.
Yan Hu +5 more
doaj +1 more source
C2238/αANP modulates apolipoprotein E through Egr-1/miR199a in vascular smooth muscle cells in vitro [PDF]
, 2015 Subjects carrying the T2238C ANP gene variant have a higher risk to suffer a stroke or myocardial infarction. The mechanisms through which T2238C/αANP exerts detrimental vascular effects need to be fully clarified.
Bianchi, Franca +9 more
core +1 more source