Results 11 to 20 of about 105,114 (272)

Rumen Microbiota Distribution Analyzed by High-Throughput Sequencing After Oral Doxycycline Administration in Beef Cattle

Frontiers in Veterinary Science, 2020
The beef cattle rumen is a heterogenous microbial ecosystem that is necessary for the host to digest food and support growth. The importance of the rumen microbiota (RM) is also widely recognized for its critical roles in metabolism and immunity.
Fengmei Chen, Guangmin Cheng, Yulin Xu, Yulin Xu, Yulin Xu, Yulin Xu, Yunzhou Wang, Qingxiang Xia, Shilin Hu   +8 more
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Doxycycline Attenuates Pig Intestinal Microbial Interactions and Changes Microbial Metabolic Pathways

Animals, 2023
Doxycycline is a therapeutic veterinary antibiotic commonly used in pig breeding. In this study, 27 fattening pigs of 33.5 ± 0.72 kg were divided equally into 3 groups.
Jiaojiao Xu, Jiadi Liang, Wenjun Chen, Xin Wen, Na Zhang, Baohua Ma, Yongde Zou, Jiandui Mi, Yan Wang, Xindi Liao, Yinbao Wu   +10 more
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Doxycycline Interferes with Zika Virus Serine Protease and Inhibits Virus Replication in Human Skin Fibroblasts

Molecules, 2021
Zika virus (ZIKV) represents a re-emerging threat to global health due to its association with congenital birth defects. ZIKV NS2B-NS3 protease is crucial for virus replication by cleaving viral polyprotein at various junctions to release viral proteins ...
Teow Chong Teoh, Sawsam J. Al-Harbi, Ammar Yasir Abdulrahman, Hussin A. Rothan   +3 more
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The inhibitory effect of doxycycline on cisplatin-sensitive and -resistant epithelial ovarian cancer.

PLoS ONE, 2014
BackgroundDetecting a new effective and hypotoxic anticancer drug is an emerging new strategy for cancer chemotherapy. Doxycycline (DC) is a kind of antibiotics but also inhibits tumorigenesis.MethodsMTT and cell invasion assay, flow cytometry, western ...
Wei Wu, Li-Hua Yu, Bei Ma, Ming-Juan Xu
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Doxycycline does not influence established abdominal aortic aneurysms in angiotensin II-infused mice. [PDF]

PLoS ONE, 2012
There is no proven medical approach to attenuating expansion and rupture of abdominal aortic aneurysms (AAAs). One approach that is currently being investigated is the use of doxycycline. Despite being primarily used as an antimicrobial drug, doxycycline
Xiaojie Xie, Hong Lu, Jessica J Moorleghen, Deborah A Howatt, Debra L Rateri, Lisa A Cassis, Alan Daugherty   +6 more
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Doxycycline as an initial treatment of bullous pemphigoid in Japanese patients

Journal of Cutaneous Immunology and Allergy, 2020
Objectives Tetracycline antibiotics have been used in bullous pemphigoid (BP) for their anti‐inflammatory effects. In Japan, tetracycline and minocycline, but not doxycycline, have been generally used in BP, although doxycycline has a better side‐effect ...
Kiyoto Kimura, Kazuhiro Kawai
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Doxycycline PEP can induce doxycycline resistance in Klebsiella pneumoniae in a Galleria mellonella model of PEP

Frontiers in Microbiology, 2023
BackgroundFour randomized controlled trials have now established that doxycycline post exposure (sex) prophylaxis (PEP) can reduce the incidence of chlamydia and syphilis in men who have sex with men.
Chris Kenyon, Chris Kenyon, Zina Gestels, Thibaut Vanbaelen, Said Abdellati, Dorien Van Den Bossche, Irith De Baetselier, Basil Britto Xavier, Basil Britto Xavier, Sheeba Santhini Manoharan-Basil   +9 more
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Doxycycline-mediated effects on persistent symptoms and systemic cytokine responses post-neuroborreliosis: a randomized, prospective, cross-over study

BMC Infectious Diseases, 2012
Background Persistent symptoms after treatment of neuroborreliosis (NB) are well-documented, although the causative mechanisms are mainly unknown. The effect of repeated antibiotic treatment has not been studied in detail.
Sjöwall Johanna, Ledel Anna, Ernerudh Jan, Ekerfelt Christina, Forsberg Pia   +4 more
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Doxycycline sensitizes renal cell carcinoma to chemotherapy by preferentially inhibiting mitochondrial translation

Journal of International Medical Research, 2021
Objectives The anti-cancer activity of doxycycline has been reported in many cancers but not renal cell carcinoma (RCC). This study aimed to determine the efficacy of doxycycline alone and in combination with paclitaxel and analyze the underlying ...
Bo Wang, Jinsong Ao, Xiaoyan Li, Weimin Yu, Dan Yu, Chengjun Qiu   +5 more
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Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo

Neurobiology of Disease, 2021
Parkinson's disease (PD) and dementia with Lewy bodies (DLB) are neurodegenerative disorders characterized by the misfolding and aggregation of alpha-synuclein (aSyn).
Antonio Dominguez-Meijide, Valeria Parrales, Eftychia Vasili, Florencia González-Lizárraga, Annekatrin König, Diana F. Lázaro, Annie Lannuzel, Stéphane Haik, Elaine Del Bel, Rosana Chehín, Rita Raisman-Vozari, Patrick P. Michel, Nicolas Bizat, Tiago Fleming Outeiro   +13 more
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