Results 21 to 30 of about 105,114 (272)

Dengue and Scrub Typhus Coinfection: A Diagnostic Dilemma

Oman Medical Journal, 2023
Due to overlapping clinical features, scrub typhus infection may be missed in presence of dengue. Concurrent infection with those two pathogens is rare and creates a diagnostic dilemma. We present a case of a 65-year-old male who was admitted with a high-
Atanu Chandra, Arkapravo Hati, Aritra Kumar Ray, Uddalak Chakraborty, Partha Sarathi Karmakar, Sugata Dasgupta   +5 more
doaj   +1 more source

Doxycycline to treat levodopa-induced dyskinesias in Parkinson's disease: a preliminary study

Arquivos de Neuro-Psiquiatria, 2023
Background Levodopa-induced dyskinesia (LID) is a common motor complication of levodopa therapy in patients with Parkinson's disease (PD). Doxycycline is a widely used and inexpensive tetracycline with anti-inflammatory properties.
Bruno Lopes Santos-Lobato, Manuelina Mariana Capellari Macruz Brito, Ângela Vieira Pimentel, Rômulo Torres Oliveira Cavalcanti, Elaine Del-Bel, Vitor Tumas   +5 more
doaj   +1 more source

The effect of laser irradiation and doxycycline application on the production of matrix metalloproteinase-8 and collagen I from cultured human periodontal ligament cells

Dental Research Journal, 2020
Background: Periodontal ligament fibroblasts (PDLF) play a key role in periodontal wound healing and tooth-supporting structures. Various approaches have been tried to enhance the fibroblastic activity such as laser irradiation or doxycycline application.
Alireza Dehdashtizadeh, Nasim Esnaashari, Shirin Zahra Farhad, Fatemeh Ejeian, Shaharam Amini   +4 more
doaj   +1 more source

Doxycycline-induced fixed drug eruption: A case series highlighting a dermatological concern in antimicrobial stewardship

International Journal of Infectious Diseases
Objectives: To describe a series of doxycycline-induced fixed drug eruptions (FDE) observed in sexual health clinics, in a context of increasing doxycycline use for sexually transmitted infection (STI) management and prophylaxis in France.
Clément Brun, Marie Danset, Romain Salle, Victor Bourdenet, Louise Jaulent, Florence Hacard, Marine Fargeas, Brigitte Milpied, Elisa Goujon, Valérie Beaulieu, Timothy Capeliez, Sébastien Fouéré, Matthieu Godinot, Marie Tauber   +13 more
doaj   +1 more source

Microwave-Assisted, One-Pot Synthesis of Doxycycline under Heterogeneous Catalysis in Water

Antibiotics, 2021
The selective synthesis of active pharmaceutical molecules is a challenging issue, particularly when attempting to make the reactions even more sustainable.
Fabio Bucciol, Elia Maffeis, Emanuela Calcio Gaudino, László Jicsinszky, Silvia Tagliapietra, Alessandro Barge, Cristina Prandi, Giancarlo Cravotto   +7 more
doaj   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Doxycycline Proniosomal Gel as Local Drug Delivery System in Periodontal Disease: A Vitro Study

Journal of Pharmacy and Bioallied Sciences
Background: Periodontitis is an inflammatory condition of the oral cavity in which microorganisms play a significant role in the pathogenesis and onset.
Dhawal Rajendra Mody, Vrushali Lathiya, Abhay P. Kolte, Vaishnavi Biradar, Vaishnavi Langde   +4 more
doaj   +1 more source

Viscoelasticity‐Induced Controllable Periodic Meso‐Textures of Liquid Crystal Polymers in Additive Manufacturing

Advanced Functional Materials, EarlyView.
Viscoelasticity‐driven instabilities are harnessed to create tunable, periodic textures in 3D‐printed liquid crystalline polymers. This study illustrates how processing parameters control these spontaneous meso‐scale patterns. These unique structural architectures unlock new possibilities for functional devices, ranging from photonic components to ...
Miaomiao Zou, Jiongyi Yan, Dick F. Firdaus, Amy Jin, Jiaxuan Li, Shushan Wang, Ran Chen, Xudong Tao, Zehao Ji, Yi Liu, Zichen Wang, Christos Margadji, Mark Kotter, J. Axel Zeitler, George G. Malliaras, Ronan Daly, Andrew Gleadall, Sebastian W. Pattinson   +17 more
wiley   +1 more source

Lowering the apoptotic threshold in colorectal cancer cells by targeting mitochondria

Cancer Cell International, 2010
Background Colorectal cancer is the third most-common cancer and the second most-common cause of cancer related death in UK. Although chemotherapy plays significant role in the treatment of colorectal cancer, morbidity and mortality due to drug ...
Sagar Jayesh, Sales Kevin, Taanman Jan-Willem, Dijk Sas, Winslet Marc   +4 more
doaj   +1 more source