Results 11 to 20 of about 16,540 (179)

DPP4 rs17574 polymorphism and elevated DPP4 levels linked to fatty liver in subclinical atherosclerosis: GEA study findings

open access: yesBiomolecules & Biomedicine
Dipeptidyl peptidase-4 (DPP4) concentrations are known to correlate with nonalcoholic fatty liver (FL), which is also associated with subclinical atherosclerosis (SA).
Gilberto Vargas-Alarcón   +6 more
doaj   +3 more sources

Glucose metabolism disorders associated with COVID-19: clinical and morphological study

open access: yesСахарный диабет, 2023
BACKGROUND. Glucose metabolism disorders (GMD) were detected both in acute and in post-COVID, however, its pathogenic aspects remain unclear.AIM. To analyze the occurrence of GMD in post-COVID patients who have had moderate and severe COVID-19 without ...
T. L. Karonova   +10 more
doaj   +1 more source

DPP4 Regulates the Th17/IL-17 Axis and Accelerates Epithelial Mesenchymal Transition to Promote Ovalbumin-Induced Asthma in Female C57BL/6J Mice

open access: yesFrontiers in Bioscience-Landmark, 2023
Background: Dipeptidyl peptidase-4 (DPP4) is a transmembrane glycoprotein, prevalent across a variety of tissues and cells and can be foundin a solubilised in peripheral blood.
Linqiao Li   +8 more
doaj   +1 more source

Reduced humidity induces skin barrier dysfunction and secretion of dipeptidyl peptidase-4 (DPP-4) in a skin-equivalent model [PDF]

open access: yesArchives of Biological Sciences, 2019
Seasonal changes can affect the physiological condition of the skin and cause various cutaneous disorders. The skin barrier function tends to worsen during winter when humidity is lower compared to other seasons.
Lee Sung Hoon   +4 more
doaj   +1 more source

Boning up on DPP4, DPP4 substrates, and DPP4-adipokine interactions: Logical reasoning and known facts about bone related effects of DPP4 inhibitors [PDF]

open access: yesBone, 2016
Dipeptidyl peptidase 4 (DPP4) is a conserved exopeptidase with an important function in protein regulation. The activity of DPP4, an enzyme which can either be anchored to the plasma membrane or circulate free in the extracellular compartment, affects the glucose metabolism, cellular signaling, migration and differentiation, oxidative stress and the ...
Lorenzo Glorie   +2 more
openaire   +3 more sources

Molecular Docking of Compounds in Moringa oleifera Lam with Dipeptidyl Peptidase-4 Receptors as Antidiabetic Candidates

open access: yesJurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2021
Background: Diabetes mellitus (DM) type 2 is a metabolic disorder that needs special attention because it can damage several organs if the severity increases. One of the treatments for diabetes mellitus (DM) type 2 is by inhibiting Dipeptidyl peptidase 4
Indah Permata Rendi   +4 more
doaj   +1 more source

Sitagliptin: a potential drug for the treatment of COVID-19?

open access: yesActa Pharmaceutica, 2021
Recently, an outbreak of a fatal coronavirus, SARS-CoV-2, has emerged from China and is rapidly spreading worldwide. Possible interaction of SARS-CoV-2 with DPP4 peptidase may partly contribute to the viral pathogenesis.
Bardaweel Sanaa K.   +2 more
doaj   +1 more source

A poor prognosis in human hepatocellular carcinoma is associated with low expression of DPP4 [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2020
This study aimed to explore the prognostic role of dipeptidyl peptidase 4 (DPP4) expression in hepatocellular carcinoma (HCC). DPP4 expression was measured in formalin-fixed paraffin-embedded specimens that were gathered from 327 HCC patients ...
Hao Yu   +4 more
doaj   +1 more source

Emerging Role of Dipeptidyl Peptidase-4 in Autoimmune Disease

open access: yesFrontiers in Immunology, 2022
Dipeptidyl-peptidase IV (DPP4), originally identified as an aminopeptidase in 1960s, is an ubiquitously expressed protease presented as either a membrane-bound or soluble form.
Jie Huang   +7 more
doaj   +1 more source

DPP4 Is a Potential Prognostic Marker of Thyroid Carcinoma and a Target for Immunotherapy

open access: yesInternational Journal of Endocrinology, 2022
DPP4 (dipeptidyl peptidase 4) is expressed in many cancers, but the relationship between DPP4 and thyroid carcinoma (THCA) is incompletely understood. We aim to explore the expression of DPP4 in THCA and the correlation between DPP4 expression with the ...
Xiaoqian Gao   +5 more
doaj   +1 more source

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