Results 11 to 20 of about 5,958,148 (313)

Analysis of the expression patterns, subcellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library

Development, 2014
Although we now have a wealth of information on the transcription patterns of all the genes in the Drosophila genome, much less is known about the properties of the encoded proteins.
Nick Lowe, Johanna S. Rees, J. Roote, Ed Ryder, Irina M. Armean, G. Johnson, Emma Drummond, Helen Spriggs, Jenny Drummond, Jose P. Magbanua, Huw W. Naylor, Bénédicte Sanson, R. Bastock, Sven Huelsmann, Vitor Trovisco, Matthias Landgraf, Seymour Knowles-Barley, J. D. Armstrong, Helen White-Cooper, Celia Hansen, Roger G. Phillips, Kathryn S. Lilley, Steven Russell, D. St Johnston   +23 more
semanticscholar   +1 more source

Distribution of DNA replication proteins in Drosophila cells

BMC Cell Biology, 2007
Background DNA replication in higher eukaryotic cells is organized in discrete subnuclear sites called replication foci (RF). During the S phase, most replication proteins assemble at the RF by interacting with PCNA via a PCNA binding domain (PBD).
Leonhardt Heinrich, Easwaran Hariharan P, Cardoso M Cristina   +2 more
doaj   +1 more source

Organization and evolution of Drosophila terminin: similarities and differences between Drosophila and human telomeres

Frontiers in Oncology, 2013
Drosophila lacks telomerase and fly telomeres are elongated by occasional transposition of three specialized retroelements. Drosophila telomeres do not terminate with GC-rich repeats and are assembled independently of the sequence of chromosome ends ...
Grazia Daniela Raffa, Giovanni eCenci, Laura eCiapponi, Maurizio eGatti   +3 more
doaj   +1 more source

A novel human polycomb binding site acts as a functional polycomb response element in Drosophila. [PDF]

PLoS ONE, 2012
Polycomb group (PcG) proteins are key chromatin regulators implicated in multiple processes including embryonic development, tissue homeostasis, genomic imprinting, X-chromosome inactivation, and germ cell differentiation.
Suresh Cuddapah, Tae-Young Roh, Kairong Cui, Cynthia C Jose, Margaret T Fuller, Keji Zhao, Xin Chen   +6 more
doaj   +1 more source

Embryonic expression pattern of a family of Drosophila proteins that interact with a central nervous system regulatory element.

Genes & Development, 1989
The protein Elf-1 interacts with a cis-acting element that is required specifically for the neuronal expression of the Drosophila dopa decarboxylase gene Ddc. Using protein purified from Drosophila embryos, we raised Elf-1-specific monoclonal antibodies.
Sarah J. Bray, Brian Burke, Nicholas H. Brown, Jay Hirsh   +3 more
semanticscholar   +1 more source

Molecular analysis of core kinetochore composition and assembly in Drosophila melanogaster.

PLoS ONE, 2007
BackgroundKinetochores are large multiprotein complexes indispensable for proper chromosome segregation. Although Drosophila is a classical model organism for studies of chromosome segregation, little is known about the organization of its kinetochores ...
Marcin R Przewloka, Wei Zhang, Patricia Costa, Vincent Archambault, Pier Paolo D'Avino, Kathryn S Lilley, Ernest D Laue, Andrew D McAinsh, David M Glover   +8 more
doaj   +1 more source

Proteomic Characterization of Drosophila melanogaster Proboscis

Biology, 2022
Drosophila melanogaster flies use their proboscis to taste and distinguish edible compounds from toxic compounds. With their proboscis, flies can detect sex pheromones at a close distance or by contact. Most of the known proteins associated with probosci’
Enisa Aruçi, Jean-Michel Saliou, Jean-François Ferveur, Loïc Briand   +3 more
doaj   +1 more source

Drosophila muscleblind codes for proteins with one and two tandem zinc finger motifs. [PDF]

PLoS ONE, 2012
Muscleblind-like proteins, Muscleblind (Mbl) in Drosophila and MBNL1-3 in vertebrates, are regulators of alternative splicing. Human MBNL1 is a key factor in the etiology of myotonic dystrophy (DM), a muscle wasting disease caused by the occurrence of ...
Uwe Irion
doaj   +1 more source

The distribution of GYR- and YLP-like motifs in Drosophila suggests a general role in cuticle assembly and other protein-protein interactions. [PDF]

PLoS ONE, 2010
BACKGROUND: Arthropod cuticle is composed predominantly of a self-assembling matrix of chitin and protein. Genes encoding structural cuticular proteins are remarkably abundant in arthropod genomes, yet there has been no systematic survey of conserved ...
R Scott Cornman
doaj   +1 more source

Organization and function of Drosophila odorant binding proteins

eLife, 2016
Odorant binding proteins (Obps) are remarkable in their number, diversity, and abundance, yet their role in olfactory coding remains unclear. They are widely believed to be required for transporting hydrophobic odorants through an aqueous lymph to ...
Nikki K Larter, Jennifer S. Sun, J. Carlson   +2 more
semanticscholar   +1 more source