Results 21 to 30 of about 5,958,148 (313)

Cross-Species Interaction between Rapidly Evolving Telomere-Specific Drosophila Proteins. [PDF]

open access: yesPLoS ONE, 2015
Telomere integrity in Drosophila melanogaster is maintained by a putative multisubunit complex called terminin that is believed to act in analogy to the mammalian shelterin complex in protecting chromosome ends from being recognized as sites of DNA ...
Balázs Vedelek   +2 more
doaj   +1 more source

Label-free quantitative proteomic analysis of adult Drosophila heads

open access: yesSTAR Protocols, 2022
Summary: LIR motif-containing proteins (LIRCPs) bind to LDS (LIR motif docking site) of Atg8-family proteins. In this protocol, we describe steps to identify Drosophila LIRCPs, in Atg8a LDS mutants we have created, via label-free quantitative proteomic ...
Yan Zhang, Ioannis P. Nezis
doaj   +1 more source

Combinatorial control of Drosophila circular RNA expression by intronic repeats, hnRNPs, and SR proteins

open access: yesGenes & Development, 2015
Kramer et al. discovered that circularization of the Drosophila laccase2 gene is regulated by both intronic repeats and trans-acting splicing factors. Unlike the previously characterized Muscleblind (Mbl) circular RNA, which requires the Mbl protein for ...
Marianne C. Kramer   +6 more
semanticscholar   +1 more source

Regulation of alternative splicing in Drosophila by 56 RNA binding proteins

open access: yesGenome Research, 2015
Alternative splicing is regulated by RNA binding proteins (RBPs) that recognize pre-mRNA sequence elements and activate or repress adjacent exons. Here, we used RNA interference and RNA-seq to identify splicing events regulated by 56 Drosophila proteins,
Angela N. Brooks   +11 more
semanticscholar   +1 more source

Biochemical and functional analysis of Drosophila-sciara chimeric sex-lethal proteins. [PDF]

open access: yesPLoS ONE, 2013
The Drosophila SXL protein controls sex determination and dosage compensation. It is a sex-specific factor controlling splicing of its own Sxl pre-mRNA (auto-regulation), tra pre-mRNA (sex determination) and msl-2 pre-mRNA plus translation of msl-2 mRNA (
María Fernanda Ruiz   +4 more
doaj   +1 more source

A modular toolset of phiC31-based fluorescent protein tagging vectors for Drosophila

open access: yesFly, 2019
The Drosophila transgenic technology and fluorescent protein fusions are powerful tools to analyze protein expression patterns, subcellular localization and protein dynamics.
Jun Luo, Pingping Shen, Jiong Chen
doaj   +1 more source

Identification and Investigation of Postsynaptic Density Homologs

open access: yesBioinformatics and Biology Insights, 2008
AMPA receptors are responsible for fast excitatory transmission in the CNS and the trafficking of these receptors has been implicated in LTP and learning and memory. These receptors reside in the postsynaptic density, a network of proteins that links the
Faith L.W. Liebl, David E. Featherstone
doaj   +1 more source

A survey of well conserved families of C2H2 zinc-finger genes in Daphnia

open access: yesBMC Genomics, 2010
Background A recent comparative genomic analysis tentatively identified roughly 40 orthologous groups of C2H2 Zinc-finger proteins that are well conserved in "bilaterians" (i.e. worms, flies, and humans).
Bai Yang, Seetharam Arun, Stuart Gary W
doaj   +1 more source

Extensive Use of RNA-Binding Proteins in Drosophila Sensory Neuron Dendrite Morphogenesis

open access: yesG3: Genes, Genomes, Genetics, 2013
The large number of RNA-binding proteins and translation factors encoded in the Drosophila and other metazoan genomes predicts widespread use of post-transcriptional regulation in cellular and developmental processes.
E. Olesnicky   +6 more
semanticscholar   +1 more source

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

open access: yesNature Communications, 2023
Generating reference maps of interactome networks illuminates genetic studies by providing a protein-centric approach to finding new components of existing pathways, complexes, and processes.
Hong-Wen Tang   +42 more
doaj   +1 more source

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