Results 181 to 190 of about 1,137,228 (316)
Response to Tutorial Drug-Drug Interactions by EM Sellers. [PDF]
Clin Transl SciDas JL, Ajavon-Hartmann AT, Schmith VGD.
europepmc +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Role of metabolites in drug-drug interactions. [PDF]
Drug Metab PharmacokinetIsoherranen N.
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Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Immunological Drug-Drug Interactions in Immune Checkpoint Inhibitor Therapy: Mechanisms, Clinical Evidence, and Artificial Intelligence. [PDF]
Curr Oncol RepYiu CH, Winardi K, Lu CY.
europepmc +1 more source
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
In a bind: a quality improvement project for reducing fluoroquinolones drug-drug interactions with multivalent cations. [PDF]
JAC Antimicrob ResistSiegrist EA +4 more
europepmc +1 more source