Results 231 to 240 of about 6,612,897 (317)

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

FEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi, Saki Sugihara, Yohei Ishibashi, Kono Yushi, Hazuki Yamauchi, Motohiro Tani   +5 more
wiley   +1 more source

Drug Transporters and Metabolizing Enzymes in Antimicrobial Drug Pharmacokinetics: Mechanisms, Drug-Drug Interactions, and Clinical Implications. [PDF]

Biomolecules
Lin K, Wang R, Li T, Zuo Y, Yang S, Dong D, Zhu Y.   +6 more
europepmc   +1 more source

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

FEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura, Kota Shoji, Michidai Nobe, Moe Ishikawa, Miu Tanaka, Akiko Okayama, Souichi Adachi, Hidemasa Matsuo   +7 more
wiley   +1 more source

Evaluation of potential drug-drug interactions and its determinants among outpatient prescriptions in six community chain pharmacies in Asmara, Eritrea: a cross-sectional study. [PDF]

Sci Rep
Abdu N, Tewelde T, Jabir N, Idrisnur S, Tesfamariam EH.   +4 more
europepmc   +1 more source

Recommendations for Management of Clinically Significant Drug-Drug Interactions With Statins and Select Agents Used in Patients With Cardiovascular Disease: A Scientific Statement From the American Heart Association

Circulation, 2016
B. Wiggins, J. Saseen, R. Page, Brent N. Reed, K. Sneed, J. Kostis, D. Lanfear, S. Virani, P. Morris   +8 more
semanticscholar   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Drug-drug interactions: The importance of medication reconciliation

Journal of Research in Pharmacy Practice, 2017
Mahin Jamshidi Makiani, Somayyeh Nasiripour, Mahnaz Hosseini, Alireza Mahbubi   +3 more
doaj   +1 more source

Patients with dementia: prevalence and type of drug-drug interactions. [PDF]

Front Pharmacol
Muñoz-Contreras MC, Cerdá B, López-Román FJ, Segarra I.   +3 more
europepmc   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Prevalence of drug-drug interactions in children with cardiac disorders receiving off-label drugs in a single centre in Pakistan: a cross-sectional study. [PDF]

BMJ Paediatr Open
Fatima A, Aamir M, Shahbaz N, Akbar S, Aslam A, Barkat K, Afaq S.   +6 more
europepmc   +1 more source