Results 251 to 260 of about 1,977,916 (307)

The Impact of Drug Delivery Systems on Pharmacokinetics and Drug-Drug Interactions in Neuropsychiatric Treatment. [PDF]

Cureus
Nammas M.
europepmc   +1 more source

DETECTING SIDE EFFECTS OF ADVERSE DRUG REACTIONS THROUGH DRUG-DRUG INTERACTIONS USING GRAPH NEURAL NETWORKS AND SELFSUPERVISED LEARNING

B. Vasantha, B Rakshitha, B Ankitha, D. SIRI MEGHANA, G Amala Nikitha   +4 more
openalex   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Effectiveness of computerised alerts to reduce drug-drug interactions (DDIs) and DDI-related harm in hospitalised patients: a quasi-experimental controlled pre-post study. [PDF]

BMJ Qual Saf
Baysari MT, Hilmer SN, Day RO, Van Dort BA, Zheng WY, Quirk R, Deidun D, Moran M, Stanceski K, Aryal N, Salem AA, Farrow L, Baker J, Hargreaves A, Grant J, Doherty P, Mekhail KZS, Westbrook JI, Li L.   +18 more
europepmc   +1 more source

Data from Modulating Treatment Outcomes of Patients with Solid Tumors in Immunotherapy Trials: A Drug Interaction Analysis from a Phase I Unit

Camila Bragança Xavier, Clark R. Andersen, JoAnn Lim, Julian H. Slade, Stacie A. Bean, Lei Kang, Hung Le, Apostolia M. Tsimberidou, Aung Naing, David S. Hong, Ecaterina E. Dumbrava, Jordi Rodón, Paula R. Pohlmann, Sarina A. Piha‐Paul, Stéphane Champiat, Timothy A. Yap, Tin‐Yun Tang, Funda Meric‐Bernstam, Siqing Fu   +18 more
openalex   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source

Estimating risk of reported versus theoretical drug-drug interactions in headaches medicine: an exhaustive comparison between DrugBank and FAERS database for abortive and preventive combinations. [PDF]

J Oral Facial Pain Headache
Kaytser V, Hakkinen I, Dave J, Zhang P.
europepmc   +1 more source

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

Clinical Pharmacology of Bulevirtide: Focus on Known and Potential Drug-Drug Interactions. [PDF]

Pharmaceutics
Billi M, Soloperto S, Bonora S, D'Avolio A, De Nicolò A.   +4 more
europepmc   +1 more source

Dual-Pathway Fusion of EHRs and Knowledge Graphs for Predicting Unseen Drug-Drug Interactions

Lee Franklin, Ma Tengfei
openalex   +1 more source