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Treatment of Drug-Induced Liver Injury
Biomedicines, 2022 Current pharmacotherapy options of drug-induced liver injury (DILI) remain under discussion and are now evaluated in this analysis. Needless to say, the use of the offending drug must be stopped as soon as DILI is suspected.
Rolf Teschke
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Drug-induced liver injury [PDF]
Nature Reviews Disease Primers, 2019 Drug-induced liver injury (DILI) is an adverse reaction to drugs or other xenobiotics that occurs either as a predictable event when an individual is exposed to toxic doses of some compounds or as an unpredictable event with many drugs in common use. Drugs can be harmful to the liver in susceptible individuals owing to genetic and environmental risk ...
Neil Kaplowitz +13 more
semanticscholar +12 more sources
Drug-induced liver injury [PDF]
Yeungnam University Journal of Medicine, 2020 Drug-induced liver injury (DILI), including herbal and dietary supplement hepatotoxicity, is often passed lightly; however, it can lead to the requirement of a liver transplant or may even cause death because of liver failure.
Jeong Ill Suh
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The Journal for Nurse Practitioners, 2009 Many drugs and environmental chemicals are capable of evoking some degree of liver injury. The liver represents a primary target for adverse drug reactions due to its central role in biotransformation and excretion of foreign compounds, its portal location within the circulation exposing it to a wide variety of substances, and its anatomic and ...
Changqing Ju, Michael P. Holt
semanticscholar +5 more sources
Ivermectin drug induced liver injury
South African Medical Journal, 2023 Ivermectin remains a popular, albeit unproven, therapy used in both the prevention and treatment of COVID-19. We discuss a patient who developed jaundice and a liver injury 3 weeks after initiating ivermectin for COVID prevention.
Mark Sonderup +2 more
doaj +4 more sources
, 2006 Drug-induced liver injury (DILI) is common and nearly all classes of medications can cause liver disease. Most cases of DILI are benign, and improve after drug withdrawal. It is important to recognize and remove the offending agent as quickly as possible to prevent the progression to chronic liver disease and/or acute liver failure.
Toshihiko Ikeda
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Drug induced liver injury: do we still need a routine liver biopsy for diagnosis today?
Annals of Hepatology, 2014 For the pathologist, the diagnosis of drug induced liver injury (DILI) is challenging, because histopathological features mimic all primary hepatic and biliary diseases, lacking changes that are specific for DILI.
Rolf Teschke, Christian Frenzel
doaj +2 more sources
Dietary patterns and the risk of tuberculosis-drug-induced liver injury: a cohort study [PDF]
Frontiers in NutritionBackground and purposeNutrition is associated with tuberculosis drug-induced liver injury (TBLI). How dietary patterns relate to tuberculosis drug-induced liver injury is still unknown.
Jinyu Wang +6 more
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Drug-induced liver injury [PDF]
Canadian Medical Association Journal, 2021 Drug-induced liver injury is estimated to have an incidence of 14–19 cases per 100 000 individuals.[1][1],[2][2] Although asymptomatic liver enzyme elevation is the most common presentation, drug-induced liver injury is the most common cause of acute liver failure in most Western countries,
Peter E. Wu, Alexander Kumachev
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Drug-induced liver injury: a comprehensive review
Therapeutic Advances in Gastroenterology, 2023 Drug-induced liver injury (DILI) remains a challenge in clinical practice and is still a diagnosis of exclusion. Although it has a low incidence amongst the general population, DILI accounts for most cases of acute liver failure with a fatality rate of ...
T. Hosack, Djamil Damry, Sujata Biswas
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