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Drug-induced liver injury [PDF]
Nature Reviews Disease Primers, 2019 Drug-induced liver injury (DILI) is an adverse reaction to drugs or other xenobiotics that occurs either as a predictable event when an individual is exposed to toxic doses of some compounds or as an unpredictable event with many drugs in common use. Drugs can be harmful to the liver in susceptible individuals owing to genetic and environmental risk ...
Andrade, Raul J +10 more
semanticscholar +10 more sources
Drug-induced liver injury [PDF]
Yeungnam University Journal of Medicine, 2020 Drug-induced liver injury (DILI), including herbal and dietary supplement hepatotoxicity, is often passed lightly; however, it can lead to the requirement of a liver transplant or may even cause death because of liver failure.
Jeong Ill Suh
doaj +4 more sources
The Journal for Nurse Practitioners, 2009 Many drugs and environmental chemicals are capable of evoking some degree of liver injury. The liver represents a primary target for adverse drug reactions due to its central role in biotransformation and excretion of foreign compounds, its portal location within the circulation exposing it to a wide variety of substances, and its anatomic and ...
Michael, Holt, Cynthia, Ju
semanticscholar +4 more sources
Epidemiology and Management of Drug-induced Liver Injury: Importance of the Updated RUCAM [PDF]
Journal of Clinical and Translational Hepatology, 2023 Drug-induced liver injury (DILI) is a major cause of acute liver injury, liver failure, and liver transplantation worldwide. In recent years, immune checkpoint inhibitors have become widely used.
Takashi Kobayashi +3 more
openalex +2 more sources
Ivermectin drug induced liver injury
South African Medical Journal, 2023 Ivermectin remains a popular, albeit unproven, therapy used in both the prevention and treatment of COVID-19. We discuss a patient who developed jaundice and a liver injury 3 weeks after initiating ivermectin for COVID prevention.
Mark Sonderup +2 more
doaj +4 more sources
Tuberculosis Drug-Induced Liver Injury
Jurnal Respirasi, 2020 Effective tuberculosis (TB) treatment requires a combination of bactericidal and/or bacteriostatic TB drugs. The combination of these regimens is the standard therapy recommended by World Health Organization (WHO).
Soedarsono Soedarsono +1 more
doaj +3 more sources
Treatment of Drug-Induced Liver Injury
Biomedicines, 2022 Current pharmacotherapy options of drug-induced liver injury (DILI) remain under discussion and are now evaluated in this analysis. Needless to say, the use of the offending drug must be stopped as soon as DILI is suspected.
Rolf Teschke
doaj +2 more sources
Semaglutide-Induced Hepatic Injury: A Rare Case of Drug Induced Liver Injury. [PDF]
Clin Case RepSemaglutide, a glucagon‐like peptide‐1 (GLP‐1) receptor agonist, is widely used for type 2 diabetes mellitus and has demonstrated hepatoprotective effects.
Kundu R, Shtoff L.
europepmc +2 more sources
Drug-induced liver injury [PDF]
Canadian Medical Association Journal, 2021 Drug-induced liver injury is estimated to have an incidence of 14–19 cases per 100 000 individuals.[1][1],[2][2] Although asymptomatic liver enzyme elevation is the most common presentation, drug-induced liver injury is the most common cause of acute liver failure in most Western countries,
Kumachev, Alexander, Wu, Peter E.
openaire +4 more sources
Features and Outcomes of 899 Patients With Drug-Induced Liver Injury: The DILIN Prospective Study
Gastroenterology, 2015 Naga Chalasani +11 more
openalex +2 more sources