Results 11 to 20 of about 402,646 (342)
Drug-induced liver injury [PDF]
Clinical Medicine, 2016 Drug-induced liver injury (DILI) remains the most common cause of acute liver failure (ALF) in the western world. Excluding paractamol overdose, nearly all DILI encountered in the clinical setting is idiosyncratic in nature, since affected individuals ...
A +12 more
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Ivermectin drug induced liver injury
South African Medical Journal, 2023 Ivermectin remains a popular, albeit unproven, therapy used in both the prevention and treatment of COVID-19. We discuss a patient who developed jaundice and a liver injury 3 weeks after initiating ivermectin for COVID prevention.
Mark Sonderup +2 more
doaj +4 more sources
Drug-induced liver injury [PDF]
Canadian Medical Association Journal, 2021 Drug-induced liver injury is estimated to have an incidence of 14–19 cases per 100 000 individuals.[1][1],[2][2] Although asymptomatic liver enzyme elevation is the most common presentation, drug-induced liver injury is the most common cause of acute liver failure in most Western countries,
Kumachev, Alexander, Wu, Peter E.
openaire +4 more sources
Drug-induced liver injury [PDF]
, 2010 Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn Skoða/Opna(view/open)Drug-induced liver injury (DILI) is a well known adverse reaction of many drugs. Direct toxic liver damage is associated with paracetamol toxicity
Einar S. Björnsson
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Drug-Induced Liver Injury [PDF]
Mayo Clinic Proceedings, 2014 Drug hepatoxicity can be nonidiosyncratic (predictable), as in the case of acetaminophen, or idiosyncratic (unpredictable). This review article focuses primarily on idiosyncratic drug-induced liver injury (DILI). New epidemiologic data suggest that approximately 20 new cases of DILI per 100,000 persons occur each year.
Michael D, Leise +2 more
+5 more sources
Drug-induced liver injury [PDF]
Nature Reviews Disease Primers, 2019 Drug-induced liver injury (DILI) is an adverse reaction to drugs or other xenobiotics that occurs either as a predictable event when an individual is exposed to toxic doses of some compounds or as an unpredictable event with many drugs in common use. Drugs can be harmful to the liver in susceptible individuals owing to genetic and environmental risk ...
Andrade, Raul J +10 more
+9 more sources
Archives of Pathology & Laboratory Medicine, 2015 ContextDrug-induced liver injury (DILI) represents a diverse set of responses following exposure to any manufactured or naturally occurring chemical compound. Drug-induced liver injury is of major concern owing to the ever increasing number of compounds introduced into the market for treatment of various diseases as well as the increasing popularity of
Kurt, Fisher +2 more
+5 more sources
Drug-Induced Liver Injury [PDF]
BioMed Research International, 2017 The incidence of drug induced liver injury (DILI) has been reported to be between 14 - 20 per 100 000 inhabitants. The diagnosis of DILI is based on an accurate anamnesis and exclusion of other liver diseases. Drugs most commonly involved in DILI belong to the classes of antibiotics and analgetics.
Eileen E. N. Almario +3 more
openaire +4 more sources
Drug Hepatotoxicity: Environmental Factors [PDF]
, 2017 Drug-induced liver injury presents as various forms of acute and chronic liver disease. There is wide geographic variation in the most commonly implicated agents.
Chalasani, Naga P., Stine, Jonathan G.
core +1 more source
The protective role of pregnane X receptor in lipopolysaccharide/D-galactosamine-induced acute liver injury. [PDF]
, 2010 The pregnane X receptor (PXR) is a nuclear receptor transcription factor regulating drug-metabolizing enzymes and transporters that facilitate xenobiotic and endobiotic detoxification.
Damjanov, Ivan +2 more
core +6 more sources