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Tuberculosis Drug-Induced Liver Injury
Effective tuberculosis (TB) treatment requires a combination of bactericidal and/or bacteriostatic TB drugs. The combination of these regimens is the standard therapy recommended by World Health Organization (WHO).
Soedarsono Soedarsono+1 more
doaj +1 more source
Treatment with gefitinib after erlotinib-induced liver injury: a case report [PDF]
INTRODUCTION: Gefitinib and erlotinib have minor differences in their chemical structures, and thus it remains unclear whether the hepatotoxicity induced by one compound is affected by the other.
Iida Tetsuya+3 more
core +2 more sources
MicroRNAs in Drug-induced Liver Injury [PDF]
Drug-induced liver injury (DILI) is a leading cause of acute liver failure, and a major reason for the recall of marketed drugs. Detection of potential liver injury is a challenge for clinical management and preclinical drug safety studies, as well as a great obstacle to the development of new, effective and safe drugs.
Ke Zen, Dong Wang, Limin Li
openaire +2 more sources
Case series and review of Ayurvedic medication induced liver injury
Background Complementary and alternative medicine use among Americans is prevalent. Originating in India, Ayurvedic medicine use in the United States has grown 57% since 2002.
Christopher M. Karousatos+3 more
doaj +1 more source
Rational choice of hepatoprotectors for drug-induced liver injury
The article deals with a review of the current literature on the clinical use of hepatoprotectors in drug-induced liver injury. The literature was searched in Scopus, Web of Science, PubMed and other databases. Risk factors, pathogenetic mechanisms of li
H.V. Osyodlo+2 more
doaj +1 more source
The protective role of pregnane X receptor in lipopolysaccharide/D-galactosamine-induced acute liver injury. [PDF]
The pregnane X receptor (PXR) is a nuclear receptor transcription factor regulating drug-metabolizing enzymes and transporters that facilitate xenobiotic and endobiotic detoxification.
Damjanov, Ivan+2 more
core +2 more sources
Background and Purpose: Drug-induced liver injury is challenging during tuberculosis treatment. There is no epidemiological data investigating the relation between dietary intake and the risk of drug-induced liver injury during tuberculosis treatment ...
Jinyu Wang+6 more
doaj +1 more source
Concentración, segregación y movilidad residencial de los extranjeros en Barcelona [PDF]
El artículo analiza la dinámica residencial de la población extranjera en la ciudad de Barcelona, considerando tres aspectos que centran su distribución: la concentración en el territorio, la segregación residencial en relación con la población de la ...
Aithal, Guruprasad P.+18 more
core +9 more sources
Stochastic Ordering under Conditional Modelling of Extreme Values: Drug-Induced Liver Injury [PDF]
Drug-induced liver injury (DILI) is a major public health issue and of serious concern for the pharmaceutical industry. Early detection of signs of a drug's potential for DILI is vital for pharmaceutical companies' evaluation of new drugs.
Box+26 more
core +1 more source
Hepatitis E Virus Detection in Liver Tissue from Patients with Suspected Drug-Induced Liver Injury [PDF]
Hepatitis E virus (HEV) infection is increasingly recognized as a cause of acute hepatitis in the industrialized world. We aimed to determine the frequency of acute Hepatitis E virus (HEV) infection in cases of suspected drug-induced liver injury (DILI),
Achim Weber+3 more
core +2 more sources