Results 121 to 130 of about 11,641 (246)

Intersections of vitamin D deficiency, HIV and chronic liver diseases

HIV Medicine, EarlyView.
Abstract Objectives Despite effective antiretroviral therapy (ART), chronic liver diseases remain a leading cause of morbidity and mortality among people with HIV, with metabolic dysfunction–associated steatotic liver disease (MASLD) now the predominant etiology. Vitamin D deficiency is also highly prevalent in this population.
Francesca Farina, Aurgho Datta, Suzanne N. Morin, Sahar Saeed, Bertrand Lebouche, Giovanni Guaraldi, Salvatore Petta, Giada Sebastiani   +7 more
wiley   +1 more source

Comparative analysis of portal hepatic infiltrating leucocytes in acute drug‐induced liver injury, idiopathic autoimmune and viral hepatitis [PDF]

, 2015
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/110851/1/cei12558 ...
Bahjat, Bonkovsky, Chalasani, Cheever, Chitturi, deLemos, Doherty, Fontana, Fontana, Holt, Ishak, Jaeschke, Jost, Kaplowitz, Kelly, Kelly, Kleiner, Kleiner, Kurachi, McFarlane, Michael, Navarro, Novobrantseva, Rockey, Rubio, Suzuki, Vogel, Washington, Wasley, Winwood   +29 more
core   +1 more source

Drug Induced Liver Injury (Dili) and Non Alcoholic Fatty Liver Disease (Nafld)

European Journal of Medical and Health Sciences, 2020
This review article includes a review of the latest literature searched on PubMed in the field of hepatotoxicity caused by drugs that have a wide daily application. The concept of the review article consists of several parts dealing with the definition of drugs induced liver injury - DILI, diagnostic challenges related to it, and the clinical spectrum ...
Nikola Malešević, Zoran Mavija, Anna Licata, Goran Bokan   +3 more
openaire   +3 more sources

Exploring Multi‐Organ Crosstalk via the TissUse HUMIMIC Chip System: Lessons Learnt So Far

Biotechnology and Bioengineering, Volume 122, Issue 11, Page 2951-2966, November 2025.
ABSTRACT Three‐dimensional (3D) in vitro cell culture models have revolutionized biomedical research by mimicking the complex 3D in vivo environment in the human body. Different types of 3D models have been established, including heterotypic systems such as, organ‐on‐a‐chips which have been further developed into multiorgan‐on‐chip systems that ...
Filsan Ahmed Abokor, Safiya Al Yazeedi, Janaeya Zuri Baher, Chung Cheung, Don D. Sin, Emmanuel Twumasi Osei   +5 more
wiley   +1 more source

Efek Pemberian Metilprednisolon Oral Terhadap Gambaran Histopatologik Hati Tikus Wistar (Rattus Norvegicus) [PDF]

, 2016
: Drug-induced liver injury (DILI) is an adverse drug reaction which vary in its clinical manifestations, ranging from an asymptomatic increase in liver enzymes to fulminant hepatic failure.
Durry, M. F. (Meilany), Lintong, P. M. (Poppy), Rifaldi, M. (Muhammad)   +2 more
core  

The diagnosis and management of idiosyncratic drug‐induced liver injury [PDF]

, 2019
Drug‐induced liver injury (DILI) is an uncommon but important cause of liver disease that can arise after exposure to a multitude of drugs and herbal and dietary supplements.
Abenavoli, Aithal, Aithal, Aithal, Amacher, Andrade, Antoine, Antoine, Antoine, Avancini, Baniasadi, Begriche, Bernal, Bernal, Björnsson, Björnsson, Björnsson, Björnsson, Chalasani, Chalasani, Chalasani, Chomchai, Church, Church, Crance, Dakhoul, Daly, Danan, Danica, Dara, Day, de, Flora, Fontana, Fontana, Fontana, Forbes, Foureau, Foureau, Ghabril, Gu, Harrill, Hayashi, Hayashi, Heurgué, Hillman, Hoofnagle, Hu, Huffman, Hung, Katsinelos, Kindmark, Kleiner, Knowles, Koch, Koga, Larkin, Lee, Lee, Lee, Liou, Loomus, Manns, Medina-Caliz, Moreno, Mosedale, Nicoletti, O'Brien, Ohmori, Ostapowicz, Pisetsky, Reuben, Robles-Diaz, Rockey, Rutherford, Sato, Schröder, Senior, Sgro, Shah, Squires, Stine, Suk, Takikawa, Tani, Thulin, Tsokos, Urban, Van Boeckel, Van Erpecum, Villa, Wang, Weber, Wong, Zhang, Zhang, Zhou, Zimmerman   +97 more
core   +1 more source

Intestinal permeability and immune‐inflammatory markers in patients with idiosyncratic drug‐induced liver injury, drug‐induced steatosis and metabolic dysfunction–associated steatotic liver disease (MASLD)

British Journal of Pharmacology, Volume 182, Issue 21, Page 5303-5316, November 2025.
Background and Purpose Adverse immuno‐inflammatory responses possibly influenced by bacterial compounds reaching the liver as a consequence of altered intestinal permeability appear to be crucial in the pathogenesis of drug‐induced liver injury and steatotic liver diseases.
Daniel E. Di Zeo‐Sánchez, Irene Díaz‐Alberola, José María Pinazo‐Bandera, Miren García‐Cortés, Judith Sanabria‐Cabrera, Mercedes Robles‐Díaz, Ismael Álvarez‐Álvarez, M. Isabel Lucena, Raúl J. Andrade, Marina Villanueva‐Paz, Camilla Stephens   +10 more
wiley   +1 more source

Reliability of causality assessment for drug, herbal and dietary supplement hepatotoxicity in the Drug‐Induced Liver Injury Network (DILIN) [PDF]

, 2014
Background & AimsBecause of the lack of objective tests to diagnose drug‐induced liver injury (DILI), causality assessment is a matter of debate. Expert opinion is often used in research and industry, but its test–retest reliability is unknown.
Barnhart, Huiman X., Chalasani, Naga, Davern, Timothy J., Fontana, Robert J., Hayashi, Paul H., Hoofnagle, Jay H., Reddy, K. Rajender, Rockey, Don C., Stolz, Andrew A., Talwalkar, Jayant A.   +9 more
core   +3 more sources

Immunology Highlights of Four Major Idiosyncratic DILI Subtypes Verified by the RUCAM: A New Evidence-Based Classification

Livers
Conventionally, drug-induced liver injury (DILI) exists in two types: idiosyncratic and intrinsic. Both types are classified as non-immune disorders, thereby ignoring that some iDILI cases may have an immune or autoimmune background that requires a ...
Rolf Teschke
doaj   +1 more source

“Too Much of a Good Thing”: Inadvertent Acetaminophen Overdose in a Low‐Weight Elderly Patient

Clinical Case Reports, Volume 13, Issue 10, October 2025.
General pharmacokinetic pathway of acetaminophen metabolism and respective oxidation, conjugation, and metabolic toxic and non‐toxic production steps. ABSTRACT Commonly used for its analgesic and anti‐pyretic properties, acetaminophen (“Tylenol”) is effective in managing generalized pain.
Theodore Joseph Miller IV, Linda Qiu, Andrew Nevin, Ronald Williams, Wilbert Beachy   +4 more
wiley   +1 more source