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Role of Genetic Polymorphisms in Drug-Induced Liver Injury (DILI)

Journal of Pharmacology, Genetics and Molecular Biology
A major cause of acute liver failure and drug reaction, drug induced liver injury (DILI) usually has a genetic component. This paper discusses the effect of genetic polymorphisms as a risk factor of DILI with reference to different inbred and genetically altered mouse models.
Srikumar Chakravarthi   +4 more
openaire   +1 more source

Diagnosis and Management of Drug-Induced Liver Injury (DILI) in Patients with Pre-Existing Liver Disease

Drug Safety, 2016
The relationship between drugs and pre-existing liver disease is complex, particularly when increased liver tests (LTs) or new symptoms emerge in patients with pre-existing liver disease during drug therapy. This requires two strategies to assess whether these changes are due to drug-induced liver injury (DILI) as a new event or due to flares of the ...
Rolf, Teschke, Gaby, Danan
openaire   +2 more sources

Pulmonary Tuberculosis with Pneumonia, Pneumoconiosis, and Drug Induced Liver Injury (DILI)

Lombok Medical Journal
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. According to the World Health Organization (WHO), TB is one of the top 10 causes of death in the world. TB is divided into pulmonary TB and extrapulmonary TB. Extra-pulmonary TB is defined as TB involving organs other than the lungs (pleura, lymph nodes, abdomen, skin ...
Ni Kadek Mega Suryantini   +3 more
openaire   +1 more source

Steatosis as risk factor for drug-induced liver injury (DILI)

Toxicology Letters, 2021
R. Kostadinova   +5 more
openaire   +1 more source

Laporan Kasus: Drug-Induced Liver Injury (Dili) pada Anak

Malahayati Nursing Journal
ABSTRACT Drug-Induced Liver Injury (DILI) is a form of liver injury that arises from the use of drugs that cause direct toxic effects or through idiosyncratic mechanisms that cannot be predicted in the pediatric population. The use of anti-tuberculosis drugs (Isoniazid, Rifampicin, and Pyrazinamide) is one of the main factors causing DILI in children ...
Emia Debora P. Karo-Karo   +2 more
openaire   +1 more source

S1203 When Is Suspected Drug Induced Liver Injury (DILI) Not DILI? An Analysis of Unlikely Cases from the U.S. Drug Induced Liver Injury Network (DILIN)

American Journal of Gastroenterology, 2022
Alfred S. Barritt   +4 more
openaire   +1 more source

WHY TARGET AYURVEDIC DRUGS FOR DRUG INDUCED LIVER INJURY (DILI)?

INDIAN DRUGS
Dear Reader, Use of herbs as medicines is as old as history of human civilization. Discovery of most of the modern medicines dates back to 19th and 20th century. Most of the potent drugs discovered have their origin in plants and they were also called “Drugs from Plants or Drugs from Nature”.
openaire   +1 more source

DILI-Stk: An Ensemble Model for the Prediction of Drug-induced Liver Injury of Drug Candidates

Current Bioinformatics, 2022
Jingyu Lee, Dokyun Na, Myeong-Sang Yu
exaly  

Drug induced liver injury – a 2023 update

Journal of Toxicology and Environmental Health - Part B: Critical Reviews, 2023
Ali Kermanizadeh, Wolfgang Moritz
exaly  

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