Results 121 to 130 of about 6,710,280 (212)

Detective Work in Drug-Induced Liver Injury: Sometimes It Is All About Interviewing the Right Witness [PDF]

, 2010
Diagnosing drug-induced liver injury (DILI) relies on history as there are no definitive diagnostic tests. We report four cases where DILI was missed or the drug misidentified when physicians relied solely on patient ...
Hayashi, Paul H., Lee, Joseph, Barritt IV, A. Sidney   +2 more
core   +1 more source

DRESS syndrome in patients with drug-induced liver injury: Characteristics and HLA risk factors

Introduction: Drug reaction with eosinophilia and systemic symptoms (DRESS) can sometimes occur in patients with drug-induced liver injury (DILI). However, detailed studies of DRESS in patients with DILI from the United States are lacking.
Phillips, Elizabeth, Arora, Nitin, Gu, Jiezhun, Drug Induced Liver Injury Network, Rahnama-Moghadam, Sahand, Vuppalanchi, Raj, Chalasani, Naga, Li, Yi Ju, Barnhart, Huiman   +8 more
core   +1 more source

Clinical Characteristics and HLA Associations of Azithromycin-Induced Liver Injury [PDF]

Background: Azithromycin (AZ) is a widely used antibiotic. The aim of this study was to characterise the clinical features, outcomes, and HLA association in patients with drug-induced liver injury (DILI) due to AZ.
Odin, Joseph A., Stolz, Andrew, Drug-Induced Liver Injury Network (DILIN), Kleiner, David E., Fontana, Robert J., Halegoua-DeMarzio, Dina, Li, Yi-Ju, Hayashi, Paul H., Navarro, Victor, Lee, William M., Ghabril, Marwan, Phillips, Elizabeth J., Conlon, Caroline, Vuppalanchi, Raj, Barnhart, Huiman, Ahmad, Jawad   +15 more
core   +1 more source

A brief overview of drug-induced liver damage

The Egyptian Journal of Internal Medicine
Drug-induced liver injury (DILI) is a prevalent disorder that can be led on by almost all drug types. The majority of benign DILI cases become better after drug discontinuation.
Soumyadip Roy, Zalak Shah, G. S. Chakraborthy   +2 more
doaj   +1 more source

Clinical and HLA associations of fluoroquinolone induced liver injury: results from the Drug-Induced Liver Injury Network

Introduction: Fluoroquinolones (FQ) have a favorable safety profile, but the risk of drug-induced liver injury (DILI) is well described. The aim of this study was to identify clinical features and HLA genetic variants associated with FQ-DILI in a large ...
Ghabril, Marwan, Gu, Jiezhun, Fontana, Robert J., Dellinger, Andrew, Barnhart, Huiman X., Choi, Gina, Kleiner, David, Hayashi, Paul H., Ahmad, Jawad, Nicoletti, Paola, Navarro, Victor, Drug-Induced Liver Injury Network   +11 more
core   +1 more source

Helicobacter pylori Eradication Therapy–Associated Drug-Induced Liver Injury in a Patient With Primary Biliary Cholangitis

Gastro Hep Advances
Drug-induced liver injury (DILI) is a rare but serious complication of Helicobacter pylori eradication therapy, especially in patients with pre-existing liver disease. We report a 75-year-old man with well-controlled primary biliary cholangitis (PBC) who
Taro Nakajima, Takefumi Kimura, Yuki Yamashita, Yugo Iwaya, Tadanobu Nagaya, Hiromitsu Mori, Shuichi Wada   +6 more
doaj   +1 more source

Drug-induced liver injury

, 2016
Drug-induced liver injury (DILI) remains the most common cause of acute liver failure (ALF) in the western world. Excluding paractamol overdose, nearly all DILI encountered in the clinical setting is idiosyncratic in nature, since affected individuals ...
Dev Katarey (16241603), Sumita Verma (4462045)   +1 more
core   +1 more source

Atorvastatin-associated liver injury: a structured narrative review of reporting signals, clinical phenotypes, and hepatic safety, 2023–2026

Frontiers in Pharmacology
BackgroundAtorvastatin is widely prescribed, yet its hepatic safety remains debated: randomized trials and biopsy-proven cohorts indicate acceptable safety, whereas pharmacovigilance data and case reports describe injury ranging from asymptomatic ...
Hao Zhang, PanLi Zhao, Hua Huang, YuQi Zeng   +3 more
doaj   +1 more source

Infliximab (IFX)-Biosimilar Induced Drug-Induced Liver Injury (DILI): A Case Report. [PDF]

Cureus, 2022
Zachou M, Pikramenos K, Panoutsakou M, Lalla E, Androutsakos T.   +4 more
europepmc   +1 more source

Drug-induced liver injury

, 2011
Epidemiology 374Pathophysiology 374Herbal drugs and alternative medicines 377Risk factors 377Clinical features 378Investigation 379Management 380Drug induced liver injury (DILI) is a variable and complex diagnosis of exclusion, as it can present in ...
R. Mark Beattie, John W.L. Puntis, Anil Dhawan   +2 more
core   +1 more source